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Q74ID0 (Q74ID0_LACJO) Unreviewed, UniProtKB/TrEMBL

Last modified May 29, 2013. Version 69. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Probable nicotinate-nucleotide adenylyltransferase HAMAP-Rule MF_00244
EC=2.7.7.18 HAMAP-Rule MF_00244
Alternative name(s):
Deamido-NAD(+) diphosphorylase HAMAP-Rule MF_00244
Deamido-NAD(+) pyrophosphorylase HAMAP-Rule MF_00244
Nicotinate mononucleotide adenylyltransferase HAMAP-Rule MF_00244
Gene names
Name:nadD HAMAP-Rule MF_00244
Ordered Locus Names:LJ_1636 EMBL AAS09408.1
OrganismLactobacillus johnsonii (strain CNCM I-12250 / La1 / NCC 533) [Complete proteome] [HAMAP] EMBL AAS09408.1
Taxonomic identifier257314 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacilli › Lactobacillales › Lactobacillaceae › Lactobacillus ›

Protein attributes

Sequence length208 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) By similarity. HAMAP-Rule MF_00244 SAAS SAAS005248

Catalytic activity

ATP + beta-nicotinate-D-ribonucleotide = diphosphate + deamido-NAD+. HAMAP-Rule MF_00244 SAAS SAAS005248

Pathway

Cofactor biosynthesis; NAD(+) biosynthesis; deamido-NAD(+) from nicotinate D-ribonucleotide: step 1/1. HAMAP-Rule MF_00244 SAAS SAAS005248

Sequence similarities

Belongs to the NadD family. HAMAP-Rule MF_00244

Sequences

Sequence LengthMass (Da)Tools
Q74ID0 [UniParc].

Last modified July 5, 2004. Version 1.
Checksum: B4D0454E97D3C26B

FASTA20823,908
        10         20         30         40         50         60 
MQCVVKEKPQ VQFEPVTSSA QQIGIMGGTF NPVHLAHLSM AEQVRKKLHL DEIWFIPNNT 

        70         80         90        100        110        120 
PPHKKIAGNI STKDRCAMLE LVTHDNPHFH VKLFEIMRGG TSYMVDTLRY LKKRAPRNQY 

       130        140        150        160        170        180 
YLIMGSDEVN DFENWREPET IALLSTLVGV RRPNYPQNPK FPMIWVDAPN LDISSSLIRQ 

       190        200 
NIATGNSIRY LVPESVRLYI KSRGLYSD

« Hide

References

[1]"The genome sequence of the probiotic intestinal bacterium Lactobacillus johnsonii NCC 533."
Pridmore R.D., Berger B., Desiere F., Vilanova D., Barretto C., Pittet A.C., Zwahlen M.C., Rouvet M., Altermann E., Barrangou R., Mollet B., Mercenier A., Klaenhammer T., Arigoni F., Schell M.A.
Proc. Natl. Acad. Sci. U.S.A. 101:2512-2517(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: CNCM I-1225 / La1 / NCC 533.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE017198 Genomic DNA. Translation: AAS09408.1.
RefSeqNP_965442.1. NC_005362.1.

3D structure databases

ProteinModelPortalQ74ID0.
ModBaseSearch...

Protein-protein interaction databases

STRING257314.LJ1636.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAS09408; AAS09408; LJ_1636.
GeneID2742559.
KEGGljo:LJ1636.
PATRIC22239573. VBILacJoh1832_1461.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK00969.
OMAHLLMANE.
ProtClustDBCLSK925428.

Enzyme and pathway databases

BioCycLJOH257314:GJN3-1454-MONOMER.
UniPathwayUPA00253; UER00332.

Family and domain databases

Gene3D3.40.50.620. 1 hit.
HAMAPMF_00244. NaMN_adenylyltr.
InterProIPR004821. Cyt_trans-like.
IPR005248. NAMN_adtrnsfrase.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
PANTHERPTHR12039. PTHR12039. 1 hit.
PfamPF01467. CTP_transf_2. 1 hit.
[Graphical view]
TIGRFAMsTIGR00125. cyt_tran_rel. 1 hit.
TIGR00482. TIGR00482. 1 hit.
ProtoNetSearch...

Entry information

Entry nameQ74ID0_LACJO
AccessionPrimary (citable) accession number: Q74ID0
Entry history
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: May 29, 2013
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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