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Q74GV9 (Q74GV9_GEOSL) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 48. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Delta-aminolevulinic acid dehydratase RuleBase RU000515
EC=4.2.1.24 RuleBase RU000515
Gene names
Name:hemB EMBL AAR33470.1
Ordered Locus Names:GSU0135
OrganismGeobacter sulfurreducens (strain ATCC 51573 / DSM 12127 / PCA)
Taxonomic identifier243231 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Deltaproteobacteria › Desulfuromonadales › Geobacteraceae › Geobacter

Protein attributes

Sequence length325 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

2 5-aminolevulinate = porphobilinogen + 2 H2O. RuleBase RU000515

Subunit structure

Homooctamer By similarity. RuleBase RU000515 PIRSR PIRSR001415-3

Sequence similarities

Belongs to the ALADH family. RuleBase RU004161

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site1951Schiff-base intermediate with substrate By similarity PIRSR PIRSR001415-1
Active site2481Schiff-base intermediate with substrate By similarity PIRSR PIRSR001415-1
Metal binding1201Zinc; catalytic By similarity PIRSR PIRSR001415-3
Metal binding1221Zinc; catalytic By similarity PIRSR PIRSR001415-3
Metal binding1301Zinc; catalytic By similarity PIRSR PIRSR001415-3
Metal binding2331Magnesium By similarity PIRSR PIRSR001415-5
Binding site2051Substrate 1 By similarity PIRSR PIRSR001415-2
Binding site2171Substrate 1 By similarity PIRSR PIRSR001415-2
Binding site2741Substrate 2 By similarity PIRSR PIRSR001415-2
Binding site3131Substrate 2 By similarity PIRSR PIRSR001415-2

Sequences

Sequence LengthMass (Da)Tools
Q74GV9 [UniParc].

Last modified July 5, 2004. Version 1.
Checksum: 17547A352AC2B327

FASTA32536,274
        10         20         30         40         50         60 
MFYPTFRARR IRGKEVFRRM VSETTLSATD LIYPMFSAFG TGIRKEISSM PGIYQQSIEH 

        70         80         90        100        110        120 
IVAEAQEVHE LGVPAVILFG IPETKDAVGS DAYAEHGIIQ ETIRALKKQV PGLAVITDVC 

       130        140        150        160        170        180 
MCEYTDHGHC GIIKDGDVDN DETLELLARE ALSHAEAGAD MVAPSDMMDG RVMAIREILD 

       190        200        210        220        230        240 
NNGYKNIPIM SYAVKYASGY YGPFREAAES TPQFGDRRSY QMDPGNRREA IREARMDVEE 

       250        260        270        280        290        300 
GADIIMVKPG LPYLDIVRDL REEFDLPVAV YNVSGEYSMI KAAGRAGWID EERVMMETLL 

       310        320 
SFKRAGADLI LTYHAKEAAR VLKRG

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE017180 Genomic DNA. Translation: AAR33470.1.
RefSeqNP_951197.1. NC_002939.4.

3D structure databases

HSSPHSSP built from PDB template 1B4K based on UniProtKB Q59643.
ProteinModelPortalQ74GV9.
SMRQ74GV9. Positions 6-323.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID2687995.
GenomeReviewsGene locus GSU0135 in contig AE017180_GR.
KEGGgsu:GSU0135.
NMPDRfig|243231.1.peg.135.
PATRIC22023018. VBIGeoSul17553_0136.
TIGRGSU0135.

Phylogenomic databases

HOGENOMHBG285270.
OMAADLCFCE.
PhylomeDBQ74GV9.
ProtClustDBPRK09283.

Family and domain databases

InterProIPR013785. Aldolase_TIM.
IPR001731. Porphobilinogen_synth.
[Graphical view]
Gene3DG3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KOK01698.
PANTHERPTHR11458. AlaD_dehydratase. 1 hit.
PfamPF00490. ALAD. 1 hit.
[Graphical view]
PIRSFPIRSF001415. Porphbilin_synth. 1 hit.
PRINTSPR00144. DALDHYDRTASE.
SMARTSM01004. ALAD. 1 hit.
[Graphical view]
PROSITEPS00169. D_ALA_DEHYDRATASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ74GV9_GEOSL
AccessionPrimary (citable) accession number: Q74GV9
Entry history
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: January 25, 2012
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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