SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q74FM4

- Q74FM4_GEOSL

UniProt

Q74FM4 - Q74FM4_GEOSL

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Submitted name:

Methyl-accepting chemotaxis sensory transducer, class 40H, putative dimer with helix-swapped heme-binding site-containing PAS domain

Gene
mcp40H-2, GSU0582
Organism
Geobacter sulfurreducens (strain ATCC 51573 / DSM 12127 / PCA)
Status
Unreviewed - Annotation score: 2 out of 5 - Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei139 – 1391Heme (covalent)Imported
Binding sitei142 – 1421Heme (covalent)Imported
Metal bindingi143 – 1431Iron (heme axial ligand); via tele nitrogenImported

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. signal transducer activity Source: InterPro
Complete GO annotation...

Keywords - Ligandi

HemeImported, Iron, Metal-binding

Enzyme and pathway databases

BioCyciGSUL243231:GH27-587-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Methyl-accepting chemotaxis sensory transducer, class 40H, putative dimer with helix-swapped heme-binding site-containing PAS domainImported
Gene namesi
Name:mcp40H-2Imported
Ordered Locus Names:GSU0582Imported
OrganismiGeobacter sulfurreducens (strain ATCC 51573 / DSM 12127 / PCA)Imported
Taxonomic identifieri243231 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaDesulfuromonadalesGeobacteraceaeGeobacter
ProteomesiUP000000577: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. integral component of membrane Source: InterPro
Complete GO annotation...

Interactioni

Protein-protein interaction databases

STRINGi243231.GSU0582.

Structurei

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3B47X-ray2.00A35-168[»]
ProteinModelPortaliQ74FM4.
SMRiQ74FM4. Positions 37-165.

Miscellaneous databases

EvolutionaryTraceiQ74FM4.

Family & Domainsi

Phylogenomic databases

HOGENOMiHOG000148080.
KOiK03406.
OMAiGIEICDV.
OrthoDBiEOG6KMB3V.

Family and domain databases

InterProiIPR003660. HAMP_linker_domain.
IPR004089. MCPsignal_dom.
[Graphical view]
PfamiPF00672. HAMP. 1 hit.
PF00015. MCPsignal. 1 hit.
[Graphical view]
SMARTiSM00304. HAMP. 1 hit.
SM00283. MA. 1 hit.
[Graphical view]
PROSITEiPS50111. CHEMOTAXIS_TRANSDUC_2. 1 hit.
PS50885. HAMP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q74FM4-1 [UniParc]FASTAAdd to Basket

« Hide

MFRTRLAFKV LAIIGITLFL GFAALGITSI WLEYNAIMDL QTRNTRGLST    50
LVVRDIGELM MAGDMAVIER YVADVRGKGA VLDLRIYDAA GRPAGKKQDA 100
PDGEVQAALT SGATAEKRHK VDGRHVLSFI VPLANEVRCQ SCHEQGARFN 150
GAMLLTTSLE EGYAGARNLT LALALVGVCS FFLLLGVMYL FFNRVIIRNI 200
GEISRRVQEI AQGEGDLTAS VPVRSSDELG VLAEGINLLV TKLREIISGL 250
YHQAGHIAIS ACRTIKETER LVASTHEQKD LSTSVAVASE EMAATLNDVA 300
VNTQRAAQLS LSVDRAAHEG MATVTETAES IDRIKDSVMA TLDTMDKLQQ 350
SSGQIGEIVG IIGDIADQTN LLALNAAIEA ARAGDSGKGF AVVANEVKVL 400
SDRTASSTRE IGTIIRSIQA EIRAVVASIA EGKDKVEVGV ERSTTARRQL 450
EDILRLAAES TDMINQIATA TEEQSATTGE ISEKISQVSG TAERVNGQME 500
QTAGIFRELS ETAEQIYGTV GRFKVGTYHD TVKGLASEMR DRVVATLERA 550
ASDRRVTLDA LFSSEYTPIP DTFPQKYRTP SDRLFDEIIS PIQEEILGRD 600
SGMYYAICVD RRGYCPSHNL RYSRPLTGNR EADKEHNRTK RIFEDRTGLR 650
CAGNTGSFLL QTYLRDTGEV MNDLSVPIVI GGRHWGAVRI GYRADD 696
Length:696
Mass (Da):75,773
Last modified:July 5, 2004 - v1
Checksum:iC5EBA03666598E34
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE017180 Genomic DNA. Translation: AAR33913.1.
RefSeqiNP_951640.1. NC_002939.5.
WP_010941245.1. NC_002939.5.

Genome annotation databases

EnsemblBacteriaiAAR33913; AAR33913; GSU0582.
GeneIDi2685861.
KEGGigsu:GSU0582.
PATRICi22023913. VBIGeoSul17553_0580.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE017180 Genomic DNA. Translation: AAR33913.1 .
RefSeqi NP_951640.1. NC_002939.5.
WP_010941245.1. NC_002939.5.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
3B47 X-ray 2.00 A 35-168 [» ]
ProteinModelPortali Q74FM4.
SMRi Q74FM4. Positions 37-165.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 243231.GSU0582.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAR33913 ; AAR33913 ; GSU0582 .
GeneIDi 2685861.
KEGGi gsu:GSU0582.
PATRICi 22023913. VBIGeoSul17553_0580.

Phylogenomic databases

HOGENOMi HOG000148080.
KOi K03406.
OMAi GIEICDV.
OrthoDBi EOG6KMB3V.

Enzyme and pathway databases

BioCyci GSUL243231:GH27-587-MONOMER.

Miscellaneous databases

EvolutionaryTracei Q74FM4.

Family and domain databases

InterProi IPR003660. HAMP_linker_domain.
IPR004089. MCPsignal_dom.
[Graphical view ]
Pfami PF00672. HAMP. 1 hit.
PF00015. MCPsignal. 1 hit.
[Graphical view ]
SMARTi SM00304. HAMP. 1 hit.
SM00283. MA. 1 hit.
[Graphical view ]
PROSITEi PS50111. CHEMOTAXIS_TRANSDUC_2. 1 hit.
PS50885. HAMP. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 51573 / DSM 12127 / PCA.
  2. "Structures and solution properties of two novel periplasmic sensor domains with c-type heme from chemotaxis proteins of Geobacter sulfurreducens: implications for signal transduction."
    Pokkuluri P.R., Pessanha M., Londer Y.Y., Wood S.J., Duke N.E., Wilton R., Catarino T., Salgueiro C.A., Schiffer M.
    J. Mol. Biol. 377:1498-1517(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.00 ANGSTROMS) OF 35-168 IN COMPLEX WITH HEME.

Entry informationi

Entry nameiQ74FM4_GEOSL
AccessioniPrimary (citable) accession number: Q74FM4
Entry historyi
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: September 3, 2014
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureImported, Complete proteome, Reference proteome

External Data

Dasty 3

Similar proteinsi