Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q74FM4

- Q74FM4_GEOSL

UniProt

Q74FM4 - Q74FM4_GEOSL

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Submitted name:

Methyl-accepting chemotaxis sensory transducer, class 40H, putative dimer with helix-swapped heme-binding site-containing PAS domain

Gene

mcp40H-2

Organism
Geobacter sulfurreducens (strain ATCC 51573 / DSM 12127 / PCA)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei139 – 1391Heme (covalent)Imported
Binding sitei142 – 1421Heme (covalent)Imported
Metal bindingi143 – 1431Iron (heme axial ligand); via tele nitrogenImported

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. signal transducer activity Source: InterPro
Complete GO annotation...

Keywords - Ligandi

HemeImported, Iron, Metal-binding

Enzyme and pathway databases

BioCyciGSUL243231:GH27-587-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Methyl-accepting chemotaxis sensory transducer, class 40H, putative dimer with helix-swapped heme-binding site-containing PAS domainImported
Gene namesi
Name:mcp40H-2Imported
Ordered Locus Names:GSU0582Imported
OrganismiGeobacter sulfurreducens (strain ATCC 51573 / DSM 12127 / PCA)Imported
Taxonomic identifieri243231 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaDesulfuromonadalesGeobacteraceaeGeobacter
ProteomesiUP000000577: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. integral component of membrane Source: InterPro
Complete GO annotation...

Interactioni

Protein-protein interaction databases

STRINGi243231.GSU0582.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3B47X-ray2.00A35-168[»]
ProteinModelPortaliQ74FM4.
SMRiQ74FM4. Positions 37-165.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ74FM4.

Family & Domainsi

Phylogenomic databases

HOGENOMiHOG000148080.
InParanoidiQ74FM4.
KOiK03406.
OMAiGIEICDV.
OrthoDBiEOG6KMB3V.

Family and domain databases

InterProiIPR003660. HAMP_linker_domain.
IPR004089. MCPsignal_dom.
[Graphical view]
PfamiPF00672. HAMP. 1 hit.
PF00015. MCPsignal. 1 hit.
[Graphical view]
SMARTiSM00304. HAMP. 1 hit.
SM00283. MA. 1 hit.
[Graphical view]
PROSITEiPS50111. CHEMOTAXIS_TRANSDUC_2. 1 hit.
PS50885. HAMP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q74FM4-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MFRTRLAFKV LAIIGITLFL GFAALGITSI WLEYNAIMDL QTRNTRGLST
60 70 80 90 100
LVVRDIGELM MAGDMAVIER YVADVRGKGA VLDLRIYDAA GRPAGKKQDA
110 120 130 140 150
PDGEVQAALT SGATAEKRHK VDGRHVLSFI VPLANEVRCQ SCHEQGARFN
160 170 180 190 200
GAMLLTTSLE EGYAGARNLT LALALVGVCS FFLLLGVMYL FFNRVIIRNI
210 220 230 240 250
GEISRRVQEI AQGEGDLTAS VPVRSSDELG VLAEGINLLV TKLREIISGL
260 270 280 290 300
YHQAGHIAIS ACRTIKETER LVASTHEQKD LSTSVAVASE EMAATLNDVA
310 320 330 340 350
VNTQRAAQLS LSVDRAAHEG MATVTETAES IDRIKDSVMA TLDTMDKLQQ
360 370 380 390 400
SSGQIGEIVG IIGDIADQTN LLALNAAIEA ARAGDSGKGF AVVANEVKVL
410 420 430 440 450
SDRTASSTRE IGTIIRSIQA EIRAVVASIA EGKDKVEVGV ERSTTARRQL
460 470 480 490 500
EDILRLAAES TDMINQIATA TEEQSATTGE ISEKISQVSG TAERVNGQME
510 520 530 540 550
QTAGIFRELS ETAEQIYGTV GRFKVGTYHD TVKGLASEMR DRVVATLERA
560 570 580 590 600
ASDRRVTLDA LFSSEYTPIP DTFPQKYRTP SDRLFDEIIS PIQEEILGRD
610 620 630 640 650
SGMYYAICVD RRGYCPSHNL RYSRPLTGNR EADKEHNRTK RIFEDRTGLR
660 670 680 690
CAGNTGSFLL QTYLRDTGEV MNDLSVPIVI GGRHWGAVRI GYRADD
Length:696
Mass (Da):75,773
Last modified:July 5, 2004 - v1
Checksum:iC5EBA03666598E34
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017180 Genomic DNA. Translation: AAR33913.1.
RefSeqiNP_951640.1. NC_002939.5.
WP_010941245.1. NC_002939.5.

Genome annotation databases

EnsemblBacteriaiAAR33913; AAR33913; GSU0582.
GeneIDi2685861.
KEGGigsu:GSU0582.
PATRICi22023913. VBIGeoSul17553_0580.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017180 Genomic DNA. Translation: AAR33913.1 .
RefSeqi NP_951640.1. NC_002939.5.
WP_010941245.1. NC_002939.5.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
3B47 X-ray 2.00 A 35-168 [» ]
ProteinModelPortali Q74FM4.
SMRi Q74FM4. Positions 37-165.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 243231.GSU0582.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAR33913 ; AAR33913 ; GSU0582 .
GeneIDi 2685861.
KEGGi gsu:GSU0582.
PATRICi 22023913. VBIGeoSul17553_0580.

Phylogenomic databases

HOGENOMi HOG000148080.
InParanoidi Q74FM4.
KOi K03406.
OMAi GIEICDV.
OrthoDBi EOG6KMB3V.

Enzyme and pathway databases

BioCyci GSUL243231:GH27-587-MONOMER.

Miscellaneous databases

EvolutionaryTracei Q74FM4.

Family and domain databases

InterProi IPR003660. HAMP_linker_domain.
IPR004089. MCPsignal_dom.
[Graphical view ]
Pfami PF00672. HAMP. 1 hit.
PF00015. MCPsignal. 1 hit.
[Graphical view ]
SMARTi SM00304. HAMP. 1 hit.
SM00283. MA. 1 hit.
[Graphical view ]
PROSITEi PS50111. CHEMOTAXIS_TRANSDUC_2. 1 hit.
PS50885. HAMP. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 51573 / DSM 12127 / PCAImported.
  2. "Structures and solution properties of two novel periplasmic sensor domains with c-type heme from chemotaxis proteins of Geobacter sulfurreducens: implications for signal transduction."
    Pokkuluri P.R., Pessanha M., Londer Y.Y., Wood S.J., Duke N.E., Wilton R., Catarino T., Salgueiro C.A., Schiffer M.
    J. Mol. Biol. 377:1498-1517(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.00 ANGSTROMS) OF 35-168 IN COMPLEX WITH HEME.

Entry informationi

Entry nameiQ74FM4_GEOSL
AccessioniPrimary (citable) accession number: Q74FM4
Entry historyi
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: October 29, 2014
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureImported, Complete proteome, Reference proteomeImported

External Data

Dasty 3