ID   Q74FM3_GEOSL            Unreviewed;       566 AA.
AC   Q74FM3;
DT   05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT   03-OCT-2012, sequence version 2.
DT   27-MAR-2024, entry version 90.
DE   SubName: Full=Methyl-accepting chemotaxis sensory transducer, class 40+24H {ECO:0000313|EMBL:AAR33914.2};
GN   Name=mcp64H-1 {ECO:0000313|EMBL:AAR33914.2};
GN   OrderedLocusNames=GSU0583 {ECO:0000313|EMBL:AAR33914.2};
OS   Geobacter sulfurreducens (strain ATCC 51573 / DSM 12127 / PCA).
OC   Bacteria; Thermodesulfobacteriota; Desulfuromonadia; Geobacterales;
OC   Geobacteraceae; Geobacter.
OX   NCBI_TaxID=243231 {ECO:0000313|EMBL:AAR33914.2, ECO:0000313|Proteomes:UP000000577};
RN   [1] {ECO:0000313|EMBL:AAR33914.2, ECO:0000313|Proteomes:UP000000577}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51573 / DSM 12127 / PCA
RC   {ECO:0000313|Proteomes:UP000000577};
RX   PubMed=14671304; DOI=10.1126/science.1088727;
RA   Methe B.A., Nelson K.E., Eisen J.A., Paulsen I.T., Nelson W.,
RA   Heidelberg J.F., Wu D., Wu M., Ward N., Beanan M.J., Dodson R.J.,
RA   Madupu R., Brinkac L.M., Daugherty S.C., DeBoy R.T., Durkin A.S., Gwinn M.,
RA   Kolonay J.F., Sullivan S.A., Haft D.H., Selengut J., Davidsen T.M.,
RA   Zafar N., White O., Tran B., Romero C., Forberger H.A., Weidman J.,
RA   Khouri H., Feldblyum T.V., Utterback T.R., Van Aken S.E., Lovley D.R.,
RA   Fraser C.M.;
RT   "Genome of Geobacter sulfurreducens: metal reduction in subsurface
RT   environments.";
RL   Science 302:1967-1969(2003).
CC   -!- SIMILARITY: Belongs to the methyl-accepting chemotaxis (MCP) protein
CC       family. {ECO:0000256|ARBA:ARBA00029447}.
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DR   EMBL; AE017180; AAR33914.2; -; Genomic_DNA.
DR   RefSeq; NP_951641.2; NC_002939.5.
DR   RefSeq; WP_010941246.1; NC_002939.5.
DR   AlphaFoldDB; Q74FM3; -.
DR   SMR; Q74FM3; -.
DR   STRING; 243231.GSU0583; -.
DR   EnsemblBacteria; AAR33914; AAR33914; GSU0583.
DR   KEGG; gsu:GSU0583; -.
DR   PATRIC; fig|243231.5.peg.581; -.
DR   eggNOG; COG0840; Bacteria.
DR   HOGENOM; CLU_000445_99_0_7; -.
DR   InParanoid; Q74FM3; -.
DR   OrthoDB; 5523945at2; -.
DR   Proteomes; UP000000577; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; IBA:GO_Central.
DR   GO; GO:0006935; P:chemotaxis; IBA:GO_Central.
DR   GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW.
DR   CDD; cd06225; HAMP; 1.
DR   Gene3D; 6.10.340.10; -; 1.
DR   Gene3D; 1.10.287.950; Methyl-accepting chemotaxis protein; 1.
DR   InterPro; IPR003660; HAMP_dom.
DR   InterPro; IPR004089; MCPsignal_dom.
DR   PANTHER; PTHR43531:SF11; METHYL-ACCEPTING CHEMOTAXIS PROTEIN 3; 1.
DR   PANTHER; PTHR43531; PROTEIN ICFG; 1.
DR   Pfam; PF00672; HAMP; 1.
DR   Pfam; PF00015; MCPsignal; 1.
DR   SMART; SM00304; HAMP; 1.
DR   SMART; SM00283; MA; 1.
DR   SUPFAM; SSF58104; Methyl-accepting chemotaxis protein (MCP) signaling domain; 3.
DR   PROSITE; PS50111; CHEMOTAXIS_TRANSDUC_2; 1.
DR   PROSITE; PS50885; HAMP; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000577};
KW   Transducer {ECO:0000256|PROSITE-ProRule:PRU00284};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..34
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        46..65
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          68..120
FT                   /note="HAMP"
FT                   /evidence="ECO:0000259|PROSITE:PS50885"
FT   DOMAIN          209..445
FT                   /note="Methyl-accepting transducer"
FT                   /evidence="ECO:0000259|PROSITE:PS50111"
SQ   SEQUENCE   566 AA;  60827 MW;  5BAD07007FB26E4B CRC64;
     MAKNLSLGSR LIRFSLTAGF IVGTAGAVMA LNYAPAAGYD RGHAHLLAGM LGCNALLSLF
     ALWMLSARKL VVRVNNLASA MDRGAEGDLT VTVTDESSDE LGQLTDNFNA MFGRLAGMVT
     RVKEAVEELR AISATVKDAV ERGLDTAEVQ TGAVQRTTDG IRAIDRSVNE VAQSVESLSR
     TASENAAAIV QMSTSIEVVA EHMEGLAREV DEVSSSIIQM AAAEKEIGRS VRVLMEDASR
     TASLVAEMDL SIRQVEKSAL ETAAISEEVL RDAELGRDSV DRTISGISEI RRSSRSASDT
     ITTLSHRVGD IGTIISVINE IAEQTKLLAL NASIIAAQAG EHGKGFAVVA NEIKELAKRT
     TSSTGEIAEI ISGLREETVR AVQAIKQAED RIGEGETLSY RSGEALEKIV DGVKMAVDQV
     GEIARTTVEQ AQGSENMRRA MERVAEMVEQ IMRATQEQAH GTELITEAAD RMKSLTGRVF
     SSTREQRDTS THIVRSSEGV THMISTIRQA SQVQAENSQK IVEAVENMET TAVNGLDTTR
     LMEEAVSRLA RQTEGLTEAM AGFKVR
//