Q74FK1 (SELD_GEOSL) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Selenide, water dikinase
EC=2.7.9.3

Alternative name(s):
Selenium donor protein
Selenophosphate synthase

Gene names

Name:	selD
Ordered Locus Names:	GSU0607

Organism

Geobacter sulfurreducens (strain ATCC 51573 / DSM 12127 / PCA)

Taxonomic identifier

243231 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Deltaproteobacteria › Desulfuromonadales › Geobacteraceae › Geobacter

Protein attributes

Sequence length	345 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Synthesizes selenophosphate from selenide and ATP By similarity. HAMAP MF_00625
Catalytic activity	ATP + selenide + H2O = AMP + selenophosphate + phosphate. HAMAP MF_00625
Cofactor	Magnesium By similarity. HAMAP MF_00625
Sequence similarities	Belongs to the selenophosphate synthase 1 family. Class I subfamily.

Ontologies

Keywords
Coding sequence diversity	Selenocysteine
Ligand	ATP-binding Magnesium Nucleotide-binding Selenium
Molecular function	Kinase Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW selenide, water dikinase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 345	345	Selenide, water dikinase HAMAP MF_00625		PRO_0000127625
Regions
	Nucleotide binding	228 – 234	7	ATP Potential
Sites
	Active site	16	1	Potential
	Site	19	1	Important for catalytic activity By similarity
Amino acid modifications
	Non-standard residue	16	1	Selenocysteine Potential

Sequences

	Sequence		Length	Mass (Da)
	Q74FK1 [UniParc]. Last modified February 26, 2008. Version 2. Checksum: 0F59BD21853E61A1	FASTA	345	35,292
	10 20 30 40 50 60 MTEGIKLTSL VKAAGUAAKL GPAGLEQALS DMVREDDPNL LVGPETADDA GVYRIGEGLA 70 80 90 100 110 120 LVETVDIITP LVDDPYTFGR IAAANALSDV FAMGGRPVTA MNLVFFPACA LPGSVLSAIL 130 140 150 160 170 180 AGGHDALREA GACLVGGHTV EDDELKYGLA VTGLISPSRV VRNATARAGD RLVLTKPLGT 190 200 210 220 230 240 GIVSTAIKAD MAPAALTAEA VRWMTMLNAE AAGLMLECGA SACTDVTGFG LVGHACEVAR 250 260 270 280 290 300 GAGVTLRLHL EQVPVLDGVM GLVADGLVPA GCYRNRDHYA PFVGAPRSDD DRLLPLFDPQ 310 320 330 340 TSGGLLLSLS PSSAGRFLAA AGDRGLFALE VGEVLPAGEC AVDIV

References

[1]

"Genome of Geobacter sulfurreducens: metal reduction in subsurface environments." Methe B.A., Nelson K.E., Eisen J.A., Paulsen I.T., Nelson W.C., Heidelberg J.F., Wu D., Wu M., Ward N.L., Beanan M.J., Dodson R.J., Madupu R., Brinkac L.M., Daugherty S.C., DeBoy R.T., Durkin A.S., Gwinn M.L., Kolonay J.F. , Sullivan S.A., Haft D.H., Selengut J., Davidsen T.M., Zafar N., White O., Tran B., Romero C., Forberger H.A., Weidman J.F., Khouri H.M., Feldblyum T.V., Utterback T.R., Van Aken S.E., Lovley D.R., Fraser C.M. Science 302:1967-1969(2003) [PubMed: 14671304] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 51573 / DSM 12127 / PCA.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE017180 Genomic DNA. Translation: AAR33938.1.
RefSeq	NP_951665.1. NC_002939.4.
3D structure databases
ProteinModelPortal	Q74FK1.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	2685373.
GenomeReviews	Gene locus GSU0607 in contig AE017180_GR.
KEGG	gsu:GSU0607.
PATRIC	22023967. VBIGeoSul17553_0606.
TIGR	GSU0607.
Phylogenomic databases
HOGENOM	HBG383791.
OMA	AGXAAKL.
PhylomeDB	Q74FK1.
ProtClustDB	CLSK827944.
Enzyme and pathway databases
BioCyc	GSUL243231:GSU_0607-MONOMER.
Family and domain databases
HAMAP	MF_00625. SelD. [Tree]
InterPro	IPR000728. AIR_synth. IPR010918. AIR_synth_C. IPR016188. PurM_N-like. IPR004536. SelD. IPR023061. SelD_I. [Graphical view]
KO	K01008.
Pfam	PF00586. AIRS. 1 hit. PF02769. AIRS_C. 1 hit. [Graphical view]
PIRSF	PIRSF036407. Selenphspht_syn. 1 hit.
SUPFAM	SSF56042. AIR_synth_C. 1 hit. SSF55326. PurM_N-like. 1 hit.
TIGRFAMs	TIGR00476. SelD. 1 hit.
ProtoNet	Search...

Entry information

Entry name

SELD_GEOSL

Accession

Primary (citable) accession number: Q74FK1

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 4, 2005
Last sequence update:	February 26, 2008
Last modified:	January 25, 2012
This is version 47 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program