ID   Q74F59_GEOSL            Unreviewed;       539 AA.
AC   Q74F59;
DT   05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2004, sequence version 1.
DT   27-MAR-2024, entry version 95.
DE   SubName: Full=Methyl-accepting chemotaxis sensory transducer, class 40H {ECO:0000313|EMBL:AAR34080.1};
GN   Name=mcp40H-23 {ECO:0000313|EMBL:AAR34080.1};
GN   OrderedLocusNames=GSU0750 {ECO:0000313|EMBL:AAR34080.1};
OS   Geobacter sulfurreducens (strain ATCC 51573 / DSM 12127 / PCA).
OC   Bacteria; Thermodesulfobacteriota; Desulfuromonadia; Geobacterales;
OC   Geobacteraceae; Geobacter.
OX   NCBI_TaxID=243231 {ECO:0000313|EMBL:AAR34080.1, ECO:0000313|Proteomes:UP000000577};
RN   [1] {ECO:0000313|EMBL:AAR34080.1, ECO:0000313|Proteomes:UP000000577}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51573 / DSM 12127 / PCA
RC   {ECO:0000313|Proteomes:UP000000577};
RX   PubMed=14671304; DOI=10.1126/science.1088727;
RA   Methe B.A., Nelson K.E., Eisen J.A., Paulsen I.T., Nelson W.,
RA   Heidelberg J.F., Wu D., Wu M., Ward N., Beanan M.J., Dodson R.J.,
RA   Madupu R., Brinkac L.M., Daugherty S.C., DeBoy R.T., Durkin A.S., Gwinn M.,
RA   Kolonay J.F., Sullivan S.A., Haft D.H., Selengut J., Davidsen T.M.,
RA   Zafar N., White O., Tran B., Romero C., Forberger H.A., Weidman J.,
RA   Khouri H., Feldblyum T.V., Utterback T.R., Van Aken S.E., Lovley D.R.,
RA   Fraser C.M.;
RT   "Genome of Geobacter sulfurreducens: metal reduction in subsurface
RT   environments.";
RL   Science 302:1967-1969(2003).
CC   -!- SIMILARITY: Belongs to the methyl-accepting chemotaxis (MCP) protein
CC       family. {ECO:0000256|ARBA:ARBA00029447}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AE017180; AAR34080.1; -; Genomic_DNA.
DR   RefSeq; NP_951807.1; NC_002939.5.
DR   RefSeq; WP_010941408.1; NC_002939.5.
DR   AlphaFoldDB; Q74F59; -.
DR   SMR; Q74F59; -.
DR   STRING; 243231.GSU0750; -.
DR   EnsemblBacteria; AAR34080; AAR34080; GSU0750.
DR   KEGG; gsu:GSU0750; -.
DR   PATRIC; fig|243231.5.peg.745; -.
DR   eggNOG; COG0840; Bacteria.
DR   HOGENOM; CLU_000445_107_27_7; -.
DR   InParanoid; Q74F59; -.
DR   OrthoDB; 9791237at2; -.
DR   Proteomes; UP000000577; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
DR   GO; GO:0006935; P:chemotaxis; IEA:InterPro.
DR   GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW.
DR   CDD; cd06225; HAMP; 1.
DR   CDD; cd11386; MCP_signal; 1.
DR   Gene3D; 1.10.287.950; Methyl-accepting chemotaxis protein; 1.
DR   InterPro; IPR004090; Chemotax_Me-accpt_rcpt.
DR   InterPro; IPR003660; HAMP_dom.
DR   InterPro; IPR004089; MCPsignal_dom.
DR   PANTHER; PTHR32089:SF112; HEME-BASED AEROTACTIC TRANSDUCER HEMAT; 1.
DR   PANTHER; PTHR32089; METHYL-ACCEPTING CHEMOTAXIS PROTEIN MCPB; 1.
DR   Pfam; PF00672; HAMP; 1.
DR   Pfam; PF00015; MCPsignal; 1.
DR   PRINTS; PR00260; CHEMTRNSDUCR.
DR   SMART; SM00304; HAMP; 1.
DR   SMART; SM00283; MA; 1.
DR   SUPFAM; SSF58104; Methyl-accepting chemotaxis protein (MCP) signaling domain; 1.
DR   PROSITE; PS50111; CHEMOTAXIS_TRANSDUC_2; 1.
DR   PROSITE; PS50885; HAMP; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000577};
KW   Transducer {ECO:0000256|ARBA:ARBA00023224, ECO:0000256|PROSITE-
KW   ProRule:PRU00284}; Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..31
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        187..206
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          208..262
FT                   /note="HAMP"
FT                   /evidence="ECO:0000259|PROSITE:PS50885"
FT   DOMAIN          267..503
FT                   /note="Methyl-accepting transducer"
FT                   /evidence="ECO:0000259|PROSITE:PS50111"
SQ   SEQUENCE   539 AA;  57888 MW;  41614DE80D0C2FB9 CRC64;
     MSVSIGRRLT LNMVWGVFVV LVLVIGNWIG MGHLEQLQAT SHEAMARSRS AQETKVIGEK
     LYRFVLESVA NPDMAGSSSK GWLNRKAEGM AKLKQLAEQT GDDAALGALV ASADKAFRGT
     VTLYETKLIP ALERGANHED IMDIDDEISM ESDNLSISLL KVAETLEKRA IAASAQYDSF
     SAKLKTFSLA LGGIGIVLLV VFSSWLSRSI MRPLRQVIAM MEDVAEGEGD LTKRLEHRSN
     DELGKLCTEF NSFVGKVHDT ISRTSSVARD VTGSVAEISR TAERLAEGAE EVASQAVMAA
     TASEEMAATS CEIAGNCQTA AQSSSRARET AARGFAMVEN TIAVMNQIAR RVRVSAESVQ
     GLGARSDQIG EIVMTIQDIA DQTNLLALNA AIEAARAGEQ GRGFAVVADE VRALAERTSR
     ATREIGEMIK GIQGETRTAV LTMEEGVKEV EAGTREAAKS GEALNEIMQG IEQLNQQMGQ
     IACAAEQQTS TTMEISGSIQ RIKDVAQETA GGAHDSARTS TRLTDLSHDL DRLVSQFRV
//