Methyl-accepting chemotaxis sensory transducer, class 40H, putative dimer with helix-swapped heme-binding site-containing PAS domain - Geobacter sulfurreducens (strain ATCC 51573 / DSM 12127 / PCA)

Preferred order of sections

Names and origin

Protein names

Submitted name:
Methyl-accepting chemotaxis sensory transducer, class 40H, putative dimer with helix-swapped heme-binding site-containing PAS domain EMBL AAR34262.1

Gene names

Name:	mcp40H-20 EMBL AAR34262.1
Ordered Locus Names:	GSU0935 EMBL AAR34262.1

Organism

Geobacter sulfurreducens (strain ATCC 51573 / DSM 12127 / PCA) [Reference proteome] [HAMAP] EMBL AAR34262.1

Taxonomic identifier

243231 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Deltaproteobacteria › Desulfuromonadales › Geobacteraceae › Geobacter ›

Protein attributes

Sequence length	528 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

Ontologies

Keywords
Ligand	Heme PDB 3B42 Iron Metal-binding
Technical term	3D-structure PDB 3B42 Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	chemotaxis Inferred from electronic annotation. Source: InterPro
Cellular_component	integral to membrane Inferred from electronic annotation. Source: InterPro
Molecular_function	metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW signal transducer activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Sites

Metal binding

60

1

Iron (heme 1 axial ligand) PDB 3B42

Metal binding

144

1

Iron (heme 3 axial ligand); via tele nitrogen PDB 3B42

Binding site

140

1

Heme 3 (covalent) PDB 3B42

Binding site

143

1

Heme 3 (covalent) PDB 3B42

Sequences

Sequence

Length

Mass (Da)

Tools

Q74EM7 [UniParc].

Last modified July 5, 2004. Version 1.
Checksum: D7ECF6A462E31D44
Show »

FASTA

528

55,874

        10         20         30         40         50         60 
MLGKKLAFKV LAILGICLSL GLFTLGSVAG WLQFRSSLDL QLKNARNLAG LIIHDIDGYM 

        70         80         90        100        110        120 
MKGDSSEVDR FISAVKSKNF IMDLRVFDEQ AKEVSPTPSQ TPNAKIQQAI AAGRTLEFKE 

       130        140        150        160        170        180 
TLDGKRTLSL VLPFPNEQRC QSCHDAGAAY LGGLLVTTSI EEGYEGARHL LIMLAVVGTV 

       190        200        210        220        230        240 
FFLVLLACMY FFFSKTIIAP IADVSRQVDE LASGGGDLTR VLPVRTQDEI GNLAGGINRL 

       250        260        270        280        290        300 
TSTIQGIITR IAQNAAQLAS AASQLNVTSA DMARSMEAVA GQATTVATAS EQMASTSQEI 

       310        320        330        340        350        360 
AGSCSIAADG AMQATETARD GAEVVERTIA VMASIADRVK DTARTVESLG SRSDQIGEII 

       370        380        390        400        410        420 
GTIEDIADQT NLLALNAAIE AARAGEQGRG FAVVADEVRA LAERTTRATK EIGSMIKSIQ 

       430        440        450        460        470        480 
QETRGAVTSM EEGVHEVTRG TDEASRSGES LQAILQRVSD VTGQVNQIAT AAEEQNATTG 

       490        500        510        520 
EITRNIQDIT DTVQSTARGA QDSAQAAGQL ASLARELQEL VGKFKIGA

« Hide

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Genome of Geobacter sulfurreducens: metal reduction in subsurface environments." Methe B.A., Nelson K.E., Eisen J.A., Paulsen I.T., Nelson W., Heidelberg J.F., Wu D., Wu M., Ward N., Beanan M.J., Dodson R.J., Madupu R., Brinkac L.M., Daugherty S.C., DeBoy R.T., Durkin A.S., Gwinn M., Kolonay J.F. Fraser C.M. Science 302:1967-1969(2003) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 51573 / DSM 12127 / PCA.
[2]	"Structures and solution properties of two novel periplasmic sensor domains with c-type heme from chemotaxis proteins of Geobacter sulfurreducens: implications for signal transduction." Pokkuluri P.R., Pessanha M., Londer Y.Y., Wood S.J., Duke N.E., Wilton R., Catarino T., Salgueiro C.A., Schiffer M. J. Mol. Biol. 377:1498-1517(2008) [PubMed] [Europe PMC] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (1.90 ANGSTROMS) OF 35-169 IN COMPLEX WITH HEME.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

AE017180 Genomic DNA. Translation: AAR34262.1.

RefSeq

NP_951989.1. NC_002939.5.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
3B42	X-ray	1.90	A/B	35-169	[»]

ProteinModelPortal

Q74EM7.

SMR

Q74EM7. Positions 37-165.

ModBase

Search...

Protein-protein interaction databases

STRING

243231.GSU0935.

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Genome annotation databases

EnsemblBacteria

AAR34262; AAR34262; GSU0935.

GeneID

2685572.

KEGG

gsu:GSU0935.

PATRIC

22024648. VBIGeoSul17553_0939.

Phylogenomic databases

HOGENOM

HOG000148080.

OMA

METGSKE.

ProtClustDB

CLSK2306746.

Enzyme and pathway databases

BioCyc

GSUL243231:GH27-920-MONOMER.

Family and domain databases

InterPro

IPR004090. Chemotax_Me-accpt_rcpt.
IPR003660. HAMP_linker_domain.
IPR004089. MCPsignal_dom.
[Graphical view]

Pfam

PF00672. HAMP. 1 hit.
PF00015. MCPsignal. 1 hit.
[Graphical view]

PRINTS

PR00260. CHEMTRNSDUCR.

SMART

SM00304. HAMP. 2 hits.
SM00283. MA. 1 hit.
[Graphical view]

PROSITE

PS50111. CHEMOTAXIS_TRANSDUC_2. 1 hit.
PS50885. HAMP. 1 hit.
[Graphical view]

ProtoNet

Search...

Other

EvolutionaryTrace

Q74EM7.

Entry information

Entry name

Q74EM7_GEOSL

Accession

Primary (citable) accession number: Q74EM7

Entry history

Integrated into UniProtKB/TrEMBL:	July 5, 2004
Last sequence update:	July 5, 2004
Last modified:	May 1, 2013
This is version 55 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)