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Q74EM7

- Q74EM7_GEOSL

UniProt

Q74EM7 - Q74EM7_GEOSL

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Protein
Submitted name:

Methyl-accepting chemotaxis sensory transducer, class 40H, putative dimer with helix-swapped heme-binding site-containing PAS domain

Gene
mcp40H-20, GSU0935
Organism
Geobacter sulfurreducens (strain ATCC 51573 / DSM 12127 / PCA)
Status
Unreviewed - Annotation score: 2 out of 5 - Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi60 – 601Iron (heme 1 axial ligand)Imported
Binding sitei140 – 1401Heme 3 (covalent)Imported
Binding sitei143 – 1431Heme 3 (covalent)Imported
Metal bindingi144 – 1441Iron (heme 3 axial ligand); via tele nitrogenImported

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. signal transducer activity Source: InterPro

GO - Biological processi

  1. chemotaxis Source: InterPro
Complete GO annotation...

Keywords - Ligandi

HemeImported, Iron, Metal-binding

Enzyme and pathway databases

BioCyciGSUL243231:GH27-944-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Methyl-accepting chemotaxis sensory transducer, class 40H, putative dimer with helix-swapped heme-binding site-containing PAS domainImported
Gene namesi
Name:mcp40H-20Imported
Ordered Locus Names:GSU0935Imported
OrganismiGeobacter sulfurreducens (strain ATCC 51573 / DSM 12127 / PCA)Imported
Taxonomic identifieri243231 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaDesulfuromonadalesGeobacteraceaeGeobacter
ProteomesiUP000000577: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. integral component of membrane Source: InterPro
Complete GO annotation...

Interactioni

Protein-protein interaction databases

STRINGi243231.GSU0935.

Structurei

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3B42X-ray1.90A/B35-169[»]
ProteinModelPortaliQ74EM7.
SMRiQ74EM7. Positions 37-165.

Miscellaneous databases

EvolutionaryTraceiQ74EM7.

Family & Domainsi

Phylogenomic databases

HOGENOMiHOG000148080.
OMAiLANEERC.
OrthoDBiEOG6KMB3V.

Family and domain databases

InterProiIPR004090. Chemotax_Me-accpt_rcpt.
IPR003660. HAMP_linker_domain.
IPR004089. MCPsignal_dom.
[Graphical view]
PfamiPF00672. HAMP. 1 hit.
PF00015. MCPsignal. 1 hit.
[Graphical view]
PRINTSiPR00260. CHEMTRNSDUCR.
SMARTiSM00304. HAMP. 2 hits.
SM00283. MA. 1 hit.
[Graphical view]
PROSITEiPS50111. CHEMOTAXIS_TRANSDUC_2. 1 hit.
PS50885. HAMP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q74EM7-1 [UniParc]FASTAAdd to Basket

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MLGKKLAFKV LAILGICLSL GLFTLGSVAG WLQFRSSLDL QLKNARNLAG    50
LIIHDIDGYM MKGDSSEVDR FISAVKSKNF IMDLRVFDEQ AKEVSPTPSQ 100
TPNAKIQQAI AAGRTLEFKE TLDGKRTLSL VLPFPNEQRC QSCHDAGAAY 150
LGGLLVTTSI EEGYEGARHL LIMLAVVGTV FFLVLLACMY FFFSKTIIAP 200
IADVSRQVDE LASGGGDLTR VLPVRTQDEI GNLAGGINRL TSTIQGIITR 250
IAQNAAQLAS AASQLNVTSA DMARSMEAVA GQATTVATAS EQMASTSQEI 300
AGSCSIAADG AMQATETARD GAEVVERTIA VMASIADRVK DTARTVESLG 350
SRSDQIGEII GTIEDIADQT NLLALNAAIE AARAGEQGRG FAVVADEVRA 400
LAERTTRATK EIGSMIKSIQ QETRGAVTSM EEGVHEVTRG TDEASRSGES 450
LQAILQRVSD VTGQVNQIAT AAEEQNATTG EITRNIQDIT DTVQSTARGA 500
QDSAQAAGQL ASLARELQEL VGKFKIGA 528
Length:528
Mass (Da):55,874
Last modified:July 5, 2004 - v1
Checksum:iD7ECF6A462E31D44
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE017180 Genomic DNA. Translation: AAR34262.1.
RefSeqiNP_951989.1. NC_002939.5.

Genome annotation databases

EnsemblBacteriaiAAR34262; AAR34262; GSU0935.
GeneIDi2685572.
KEGGigsu:GSU0935.
PATRICi22024648. VBIGeoSul17553_0939.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE017180 Genomic DNA. Translation: AAR34262.1 .
RefSeqi NP_951989.1. NC_002939.5.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
3B42 X-ray 1.90 A/B 35-169 [» ]
ProteinModelPortali Q74EM7.
SMRi Q74EM7. Positions 37-165.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 243231.GSU0935.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAR34262 ; AAR34262 ; GSU0935 .
GeneIDi 2685572.
KEGGi gsu:GSU0935.
PATRICi 22024648. VBIGeoSul17553_0939.

Phylogenomic databases

HOGENOMi HOG000148080.
OMAi LANEERC.
OrthoDBi EOG6KMB3V.

Enzyme and pathway databases

BioCyci GSUL243231:GH27-944-MONOMER.

Miscellaneous databases

EvolutionaryTracei Q74EM7.

Family and domain databases

InterProi IPR004090. Chemotax_Me-accpt_rcpt.
IPR003660. HAMP_linker_domain.
IPR004089. MCPsignal_dom.
[Graphical view ]
Pfami PF00672. HAMP. 1 hit.
PF00015. MCPsignal. 1 hit.
[Graphical view ]
PRINTSi PR00260. CHEMTRNSDUCR.
SMARTi SM00304. HAMP. 2 hits.
SM00283. MA. 1 hit.
[Graphical view ]
PROSITEi PS50111. CHEMOTAXIS_TRANSDUC_2. 1 hit.
PS50885. HAMP. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 51573 / DSM 12127 / PCA.
  2. "Structures and solution properties of two novel periplasmic sensor domains with c-type heme from chemotaxis proteins of Geobacter sulfurreducens: implications for signal transduction."
    Pokkuluri P.R., Pessanha M., Londer Y.Y., Wood S.J., Duke N.E., Wilton R., Catarino T., Salgueiro C.A., Schiffer M.
    J. Mol. Biol. 377:1498-1517(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (1.90 ANGSTROMS) OF 35-169 IN COMPLEX WITH HEME.

Entry informationi

Entry nameiQ74EM7_GEOSL
AccessioniPrimary (citable) accession number: Q74EM7
Entry historyi
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: July 9, 2014
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureImported, Complete proteome, Reference proteome

External Data

Dasty 3

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