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Q74EM7

- Q74EM7_GEOSL

UniProt

Q74EM7 - Q74EM7_GEOSL

Protein
Submitted name:

Methyl-accepting chemotaxis sensory transducer, class 40H, putative dimer with helix-swapped heme-binding site-containing PAS domain

Gene

mcp40H-20

Organism
Geobacter sulfurreducens (strain ATCC 51573 / DSM 12127 / PCA)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 64 (01 Oct 2014)
      Sequence version 1 (05 Jul 2004)
      Previous versions | rss
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    Functioni

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi60 – 601Iron (heme 1 axial ligand)Imported
    Binding sitei140 – 1401Heme 3 (covalent)Imported
    Binding sitei143 – 1431Heme 3 (covalent)Imported
    Metal bindingi144 – 1441Iron (heme 3 axial ligand); via tele nitrogenImported

    GO - Molecular functioni

    1. metal ion binding Source: UniProtKB-KW
    2. signal transducer activity Source: InterPro

    GO - Biological processi

    1. chemotaxis Source: InterPro

    Keywords - Ligandi

    HemeImported, Iron, Metal-binding

    Enzyme and pathway databases

    BioCyciGSUL243231:GH27-944-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Methyl-accepting chemotaxis sensory transducer, class 40H, putative dimer with helix-swapped heme-binding site-containing PAS domainImported
    Gene namesi
    Name:mcp40H-20Imported
    Ordered Locus Names:GSU0935Imported
    OrganismiGeobacter sulfurreducens (strain ATCC 51573 / DSM 12127 / PCA)Imported
    Taxonomic identifieri243231 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaDesulfuromonadalesGeobacteraceaeGeobacter
    ProteomesiUP000000577: Chromosome

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: InterPro

    Interactioni

    Protein-protein interaction databases

    STRINGi243231.GSU0935.

    Structurei

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    3B42X-ray1.90A/B35-169[»]
    ProteinModelPortaliQ74EM7.
    SMRiQ74EM7. Positions 37-165.
    ModBaseiSearch...
    MobiDBiSearch...

    Miscellaneous databases

    EvolutionaryTraceiQ74EM7.

    Family & Domainsi

    Phylogenomic databases

    HOGENOMiHOG000148080.
    OMAiLANEERC.
    OrthoDBiEOG6KMB3V.

    Family and domain databases

    InterProiIPR004090. Chemotax_Me-accpt_rcpt.
    IPR003660. HAMP_linker_domain.
    IPR004089. MCPsignal_dom.
    [Graphical view]
    PfamiPF00672. HAMP. 1 hit.
    PF00015. MCPsignal. 1 hit.
    [Graphical view]
    PRINTSiPR00260. CHEMTRNSDUCR.
    SMARTiSM00304. HAMP. 2 hits.
    SM00283. MA. 1 hit.
    [Graphical view]
    PROSITEiPS50111. CHEMOTAXIS_TRANSDUC_2. 1 hit.
    PS50885. HAMP. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q74EM7-1 [UniParc]FASTAAdd to Basket

    « Hide

    MLGKKLAFKV LAILGICLSL GLFTLGSVAG WLQFRSSLDL QLKNARNLAG    50
    LIIHDIDGYM MKGDSSEVDR FISAVKSKNF IMDLRVFDEQ AKEVSPTPSQ 100
    TPNAKIQQAI AAGRTLEFKE TLDGKRTLSL VLPFPNEQRC QSCHDAGAAY 150
    LGGLLVTTSI EEGYEGARHL LIMLAVVGTV FFLVLLACMY FFFSKTIIAP 200
    IADVSRQVDE LASGGGDLTR VLPVRTQDEI GNLAGGINRL TSTIQGIITR 250
    IAQNAAQLAS AASQLNVTSA DMARSMEAVA GQATTVATAS EQMASTSQEI 300
    AGSCSIAADG AMQATETARD GAEVVERTIA VMASIADRVK DTARTVESLG 350
    SRSDQIGEII GTIEDIADQT NLLALNAAIE AARAGEQGRG FAVVADEVRA 400
    LAERTTRATK EIGSMIKSIQ QETRGAVTSM EEGVHEVTRG TDEASRSGES 450
    LQAILQRVSD VTGQVNQIAT AAEEQNATTG EITRNIQDIT DTVQSTARGA 500
    QDSAQAAGQL ASLARELQEL VGKFKIGA 528
    Length:528
    Mass (Da):55,874
    Last modified:July 5, 2004 - v1
    Checksum:iD7ECF6A462E31D44
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE017180 Genomic DNA. Translation: AAR34262.1.
    RefSeqiNP_951989.1. NC_002939.5.

    Genome annotation databases

    EnsemblBacteriaiAAR34262; AAR34262; GSU0935.
    GeneIDi2685572.
    KEGGigsu:GSU0935.
    PATRICi22024648. VBIGeoSul17553_0939.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE017180 Genomic DNA. Translation: AAR34262.1 .
    RefSeqi NP_951989.1. NC_002939.5.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    3B42 X-ray 1.90 A/B 35-169 [» ]
    ProteinModelPortali Q74EM7.
    SMRi Q74EM7. Positions 37-165.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 243231.GSU0935.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAR34262 ; AAR34262 ; GSU0935 .
    GeneIDi 2685572.
    KEGGi gsu:GSU0935.
    PATRICi 22024648. VBIGeoSul17553_0939.

    Phylogenomic databases

    HOGENOMi HOG000148080.
    OMAi LANEERC.
    OrthoDBi EOG6KMB3V.

    Enzyme and pathway databases

    BioCyci GSUL243231:GH27-944-MONOMER.

    Miscellaneous databases

    EvolutionaryTracei Q74EM7.

    Family and domain databases

    InterProi IPR004090. Chemotax_Me-accpt_rcpt.
    IPR003660. HAMP_linker_domain.
    IPR004089. MCPsignal_dom.
    [Graphical view ]
    Pfami PF00672. HAMP. 1 hit.
    PF00015. MCPsignal. 1 hit.
    [Graphical view ]
    PRINTSi PR00260. CHEMTRNSDUCR.
    SMARTi SM00304. HAMP. 2 hits.
    SM00283. MA. 1 hit.
    [Graphical view ]
    PROSITEi PS50111. CHEMOTAXIS_TRANSDUC_2. 1 hit.
    PS50885. HAMP. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 51573 / DSM 12127 / PCAImported.
    2. "Structures and solution properties of two novel periplasmic sensor domains with c-type heme from chemotaxis proteins of Geobacter sulfurreducens: implications for signal transduction."
      Pokkuluri P.R., Pessanha M., Londer Y.Y., Wood S.J., Duke N.E., Wilton R., Catarino T., Salgueiro C.A., Schiffer M.
      J. Mol. Biol. 377:1498-1517(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (1.90 ANGSTROMS) OF 35-169 IN COMPLEX WITH HEME.

    Entry informationi

    Entry nameiQ74EM7_GEOSL
    AccessioniPrimary (citable) accession number: Q74EM7
    Entry historyi
    Integrated into UniProtKB/TrEMBL: July 5, 2004
    Last sequence update: July 5, 2004
    Last modified: October 1, 2014
    This is version 64 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    3D-structureImported, Complete proteome, Reference proteomeImported

    External Data

    Dasty 3