Q74ED9 (GLGA1_GEOSL) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Glycogen synthase 1
EC=2.4.1.21

Alternative name(s):
Starch [bacterial glycogen] synthase 1

Gene names

Name:	glgA1
Synonyms:	glgA-1
Ordered Locus Names:	GSU1023

Organism

Geobacter sulfurreducens (strain ATCC 51573 / DSM 12127 / PCA)

Taxonomic identifier

243231 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Deltaproteobacteria › Desulfuromonadales › Geobacteraceae › Geobacter

Protein attributes

Sequence length	501 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Synthesizes alpha-1,4-glucan chains using ADP-glucose. HAMAP MF_00484
Catalytic activity	ADP-glucose + (1,4-alpha-D-glucosyl)(n) = ADP + (1,4-alpha-D-glucosyl)(n+1). HAMAP MF_00484
Pathway	Glycan biosynthesis; glycogen biosynthesis. HAMAP MF_00484
Sequence similarities	Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.

Ontologies

Keywords
Biological process	Glycogen biosynthesis
Molecular function	Glycosyltransferase Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	glycogen biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	starch synthase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 501	501	Glycogen synthase 1 HAMAP MF_00484		PRO_0000188617
Sites
	Binding site	18	1	ADP-glucose By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q74ED9 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: 8D89020F288AB2DB	FASTA	501	56,222
	10 20 30 40 50 60 MTRLNILMAA SECVPFAKEG GLADVVGVLP KYLAHMGHDV RVVMPLYSRI DPERFGLERL 70 80 90 100 110 120 PGVLVVPMGI MGNQYCGVWE GRLPGSAVPV YFLEHEGYYG REGLYEEDNV GYMDNDNRFI 130 140 150 160 170 180 FLSRAAMELP KLIGFAPDVF HAHDWHTAAV PVFLNTLYRD DPLVGGAASV LTVHNMQHQG 190 200 210 220 230 240 NFYPGAMEVL GIGWEHFTFL GLEKDNQTNL LKGGLYHATV LNTVSEGYAR EMQTPEYGWG 250 260 270 280 290 300 LDGVVRARSA DLVGILNGVD YEEWNPETDP HIVANYSRSD LSGKKLCKRD VQRFFGLPER 310 320 330 340 350 360 DDVPLFGLVG RLVKQKGIDI LAEAIHRILA LDVQVVMLGA GEPWSHFYFG DVRNEYPEKF 370 380 390 400 410 420 GLYIGYNNGL SHRIEAGSDF FVMPSAFEPC GLNQMYSLRY GTLPIVRATG GLDDSVENFD 430 440 450 460 470 480 EQNLTGNGFK FWSHDADALF DTVGWTVHTW YRRKDAMAAL IGNAMAKRFT WEDSAARYEE 490 500 LYCRALRKRL GVGVFVRRFG G

References

[1]

"Genome of Geobacter sulfurreducens: metal reduction in subsurface environments." Methe B.A., Nelson K.E., Eisen J.A., Paulsen I.T., Nelson W.C., Heidelberg J.F., Wu D., Wu M., Ward N.L., Beanan M.J., Dodson R.J., Madupu R., Brinkac L.M., Daugherty S.C., DeBoy R.T., Durkin A.S., Gwinn M.L., Kolonay J.F. , Sullivan S.A., Haft D.H., Selengut J., Davidsen T.M., Zafar N., White O., Tran B., Romero C., Forberger H.A., Weidman J.F., Khouri H.M., Feldblyum T.V., Utterback T.R., Van Aken S.E., Lovley D.R., Fraser C.M. Science 302:1967-1969(2003) [PubMed: 14671304] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 51573 / DSM 12127 / PCA.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE017180 Genomic DNA. Translation: AAR34350.1.
RefSeq	NP_952077.1. NC_002939.4.
3D structure databases
ProteinModelPortal	Q74ED9.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	2685960.
GenomeReviews	Gene locus GSU1023 in contig AE017180_GR.
KEGG	gsu:GSU1023.
NMPDR	fig|243231.1.peg.1015.
PATRIC	22024816. VBIGeoSul17553_1023.
TIGR	GSU1023.
Phylogenomic databases
HOGENOM	HBG596384.
OMA	GIYHATL.
PhylomeDB	Q74ED9.
ProtClustDB	CLSK924464.
Enzyme and pathway databases
BioCyc	GSUL243231:GSU_1023-MONOMER.
Family and domain databases
HAMAP	MF_00484. Glycogen_synth. [Tree]
InterPro	IPR001296. Glyco_trans_1. IPR011835. Glycogen/starch_synth. IPR013534. Starch_synth_cat_dom. [Graphical view]
KO	K00703.
Pfam	PF08323. Glyco_transf_5. 1 hit. PF00534. Glycos_transf_1. 1 hit. [Graphical view]
TIGRFAMs	TIGR02095. GlgA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

GLGA1_GEOSL

Accession

Primary (citable) accession number: Q74ED9

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 15, 2005
Last sequence update:	July 5, 2004
Last modified:	January 25, 2012
This is version 43 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program