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Protein

Ribonuclease Y

Gene

rny

Organism
Geobacter sulfurreducens (strain ATCC 51573 / DSM 12127 / PCA)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Endoribonuclease that initiates mRNA decay.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Endonuclease, Hydrolase, Nuclease

Keywords - Ligandi

RNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Ribonuclease YUniRule annotation (EC:3.1.-.-UniRule annotation)
Short name:
RNase YUniRule annotation
Gene namesi
Name:rnyUniRule annotation
Ordered Locus Names:GSU1137
OrganismiGeobacter sulfurreducens (strain ATCC 51573 / DSM 12127 / PCA)
Taxonomic identifieri243231 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaDesulfuromonadalesGeobacteraceaeGeobacter
Proteomesi
  • UP000000577 Componenti: Chromosome

Subcellular locationi

  • Cell membrane UniRule annotation; Single-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei3 – 23HelicalUniRule annotationAdd BLAST21

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003448821 – 520Ribonuclease YAdd BLAST520

Interactioni

Protein-protein interaction databases

STRINGi243231.GSU1137.

Structurei

3D structure databases

ProteinModelPortaliQ74E27.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini210 – 273KHUniRule annotationAdd BLAST64
Domaini336 – 427HDUniRule annotationAdd BLAST92

Sequence similaritiesi

Belongs to the RNase Y family.UniRule annotation
Contains 1 HD domain.UniRule annotation
Contains 1 KH domain.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105E4Y. Bacteria.
COG1418. LUCA.
HOGENOMiHOG000221256.
InParanoidiQ74E27.
KOiK18682.
OMAiYYARGQA.
OrthoDBiPOG091H00E1.

Family and domain databases

Gene3Di1.10.3210.10. 1 hit.
3.30.1370.10. 1 hit.
HAMAPiMF_00335. RNase_Y. 1 hit.
InterProiIPR003607. HD/PDEase_dom.
IPR006674. HD_domain.
IPR006675. HDIG_dom.
IPR004087. KH_dom.
IPR004088. KH_dom_type_1.
IPR017705. Ribonuclease_Y.
IPR022711. RNase_Y_N.
[Graphical view]
PfamiPF12072. DUF3552. 1 hit.
PF01966. HD. 1 hit.
PF00013. KH_1. 1 hit.
[Graphical view]
SMARTiSM00471. HDc. 1 hit.
SM00322. KH. 1 hit.
[Graphical view]
SUPFAMiSSF54791. SSF54791. 1 hit.
TIGRFAMsiTIGR00277. HDIG. 1 hit.
TIGR03319. RNase_Y. 1 hit.
PROSITEiPS50084. KH_TYPE_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q74E27-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKIELAIIFI VLAAGAGFLI GNLLRKKLSD SLVSKAEELA SRIVEDAKRE
60 70 80 90 100
AETISKEAAL QAKDVVYQAK ADFEREAKEK HKDLQTLEKR LQQKEENLDK
110 120 130 140 150
KMNLFDQRDA DLTKKEQGIL AREQSLNRKE ESLDALVAEQ RAKLEQISGM
160 170 180 190 200
SSAEAKKILM DAMESEAKLD AAKRIKAIEE EARETADKKS KEIISLAVQR
210 220 230 240 250
YAGEYVAEKT VSVVALPSDE MKGRIIGREG RNIRALEAAT GIDLIIDDTP
260 270 280 290 300
EAVILSGFNP VRREVAKIAL EKLITDGRIH PGRIEEVVAK AEEEVEQAVK
310 320 330 340 350
EAGDQAAFDL GVHGIHPEIL KLIGRLKYRT SYSQNVYQHS LEVAFLCGIM
360 370 380 390 400
ASELGINVKQ AKRAGLLHDL GKAVDHEVEG SHAVIGAELA RKYGESPKIV
410 420 430 440 450
HAIMAHHEDE KPNSILAVLV QAADALSGAR PGARREMMET YVKRLEDLER
460 470 480 490 500
ISCSFGGVNN SFAIQAGREI RVMVSSEEVS DERAVLLAKD IAKKIEAEMT
510 520
YPGQIKVNVI RETRAIEYAR
Length:520
Mass (Da):57,556
Last modified:July 5, 2004 - v1
Checksum:iD38730EA0FDA1F08
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017180 Genomic DNA. Translation: AAR34513.1.
RefSeqiNP_952190.1. NC_002939.5.
WP_010941798.1. NC_002939.5.

Genome annotation databases

EnsemblBacteriaiAAR34513; AAR34513; GSU1137.
GeneIDi2685899.
KEGGigsu:GSU1137.
PATRICi22025034. VBIGeoSul17553_1132.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017180 Genomic DNA. Translation: AAR34513.1.
RefSeqiNP_952190.1. NC_002939.5.
WP_010941798.1. NC_002939.5.

3D structure databases

ProteinModelPortaliQ74E27.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi243231.GSU1137.

Protocols and materials databases

DNASUi2685899.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAR34513; AAR34513; GSU1137.
GeneIDi2685899.
KEGGigsu:GSU1137.
PATRICi22025034. VBIGeoSul17553_1132.

Phylogenomic databases

eggNOGiENOG4105E4Y. Bacteria.
COG1418. LUCA.
HOGENOMiHOG000221256.
InParanoidiQ74E27.
KOiK18682.
OMAiYYARGQA.
OrthoDBiPOG091H00E1.

Family and domain databases

Gene3Di1.10.3210.10. 1 hit.
3.30.1370.10. 1 hit.
HAMAPiMF_00335. RNase_Y. 1 hit.
InterProiIPR003607. HD/PDEase_dom.
IPR006674. HD_domain.
IPR006675. HDIG_dom.
IPR004087. KH_dom.
IPR004088. KH_dom_type_1.
IPR017705. Ribonuclease_Y.
IPR022711. RNase_Y_N.
[Graphical view]
PfamiPF12072. DUF3552. 1 hit.
PF01966. HD. 1 hit.
PF00013. KH_1. 1 hit.
[Graphical view]
SMARTiSM00471. HDc. 1 hit.
SM00322. KH. 1 hit.
[Graphical view]
SUPFAMiSSF54791. SSF54791. 1 hit.
TIGRFAMsiTIGR00277. HDIG. 1 hit.
TIGR03319. RNase_Y. 1 hit.
PROSITEiPS50084. KH_TYPE_1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiRNY_GEOSL
AccessioniPrimary (citable) accession number: Q74E27
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 22, 2008
Last sequence update: July 5, 2004
Last modified: November 2, 2016
This is version 90 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.