ID   Q74DM2_GEOSL            Unreviewed;       962 AA.
AC   Q74DM2;
DT   05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2004, sequence version 1.
DT   27-MAR-2024, entry version 99.
DE   SubName: Full=Methyl-accepting chemotaxis sensory transducer, class 34H {ECO:0000313|EMBL:AAR34670.1};
GN   Name=mcp34H-7 {ECO:0000313|EMBL:AAR34670.1};
GN   OrderedLocusNames=GSU1294 {ECO:0000313|EMBL:AAR34670.1};
OS   Geobacter sulfurreducens (strain ATCC 51573 / DSM 12127 / PCA).
OC   Bacteria; Thermodesulfobacteriota; Desulfuromonadia; Geobacterales;
OC   Geobacteraceae; Geobacter.
OX   NCBI_TaxID=243231 {ECO:0000313|EMBL:AAR34670.1, ECO:0000313|Proteomes:UP000000577};
RN   [1] {ECO:0000313|EMBL:AAR34670.1, ECO:0000313|Proteomes:UP000000577}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51573 / DSM 12127 / PCA
RC   {ECO:0000313|Proteomes:UP000000577};
RX   PubMed=14671304; DOI=10.1126/science.1088727;
RA   Methe B.A., Nelson K.E., Eisen J.A., Paulsen I.T., Nelson W.,
RA   Heidelberg J.F., Wu D., Wu M., Ward N., Beanan M.J., Dodson R.J.,
RA   Madupu R., Brinkac L.M., Daugherty S.C., DeBoy R.T., Durkin A.S., Gwinn M.,
RA   Kolonay J.F., Sullivan S.A., Haft D.H., Selengut J., Davidsen T.M.,
RA   Zafar N., White O., Tran B., Romero C., Forberger H.A., Weidman J.,
RA   Khouri H., Feldblyum T.V., Utterback T.R., Van Aken S.E., Lovley D.R.,
RA   Fraser C.M.;
RT   "Genome of Geobacter sulfurreducens: metal reduction in subsurface
RT   environments.";
RL   Science 302:1967-1969(2003).
CC   -!- SIMILARITY: Belongs to the methyl-accepting chemotaxis (MCP) protein
CC       family. {ECO:0000256|ARBA:ARBA00029447}.
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DR   EMBL; AE017180; AAR34670.1; -; Genomic_DNA.
DR   RefSeq; NP_952347.1; NC_002939.5.
DR   RefSeq; WP_010941949.1; NC_002939.5.
DR   AlphaFoldDB; Q74DM2; -.
DR   SMR; Q74DM2; -.
DR   STRING; 243231.GSU1294; -.
DR   EnsemblBacteria; AAR34670; AAR34670; GSU1294.
DR   KEGG; gsu:GSU1294; -.
DR   PATRIC; fig|243231.5.peg.1290; -.
DR   eggNOG; COG0840; Bacteria.
DR   HOGENOM; CLU_000445_107_20_7; -.
DR   InParanoid; Q74DM2; -.
DR   OrthoDB; 5390881at2; -.
DR   Proteomes; UP000000577; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; IBA:GO_Central.
DR   GO; GO:0006935; P:chemotaxis; IBA:GO_Central.
DR   GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW.
DR   CDD; cd06225; HAMP; 1.
DR   CDD; cd17527; HAMP_II; 2.
DR   CDD; cd17528; HAMP_III; 2.
DR   CDD; cd19411; MCP2201-like_sensor; 1.
DR   CDD; cd11386; MCP_signal; 1.
DR   Gene3D; 1.20.120.1530; -; 3.
DR   Gene3D; 6.10.340.10; -; 1.
DR   Gene3D; 1.10.287.950; Methyl-accepting chemotaxis protein; 1.
DR   InterPro; IPR003660; HAMP_dom.
DR   InterPro; IPR041395; HAMP_N3.
DR   InterPro; IPR024478; HlyB_4HB_MCP.
DR   InterPro; IPR004089; MCPsignal_dom.
DR   InterPro; IPR047347; YvaQ-like_sensor.
DR   PANTHER; PTHR43531:SF11; METHYL-ACCEPTING CHEMOTAXIS PROTEIN 3; 1.
DR   PANTHER; PTHR43531; PROTEIN ICFG; 1.
DR   Pfam; PF12729; 4HB_MCP_1; 1.
DR   Pfam; PF00672; HAMP; 1.
DR   Pfam; PF18947; HAMP_2; 2.
DR   Pfam; PF18575; HAMP_N3; 2.
DR   Pfam; PF00015; MCPsignal; 1.
DR   SMART; SM00304; HAMP; 3.
DR   SMART; SM00283; MA; 1.
DR   SUPFAM; SSF158472; HAMP domain-like; 1.
DR   SUPFAM; SSF58104; Methyl-accepting chemotaxis protein (MCP) signaling domain; 1.
DR   PROSITE; PS50111; CHEMOTAXIS_TRANSDUC_2; 1.
DR   PROSITE; PS50885; HAMP; 3.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000577};
KW   Transducer {ECO:0000256|PROSITE-ProRule:PRU00284};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..30
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          211..263
FT                   /note="HAMP"
FT                   /evidence="ECO:0000259|PROSITE:PS50885"
FT   DOMAIN          302..354
FT                   /note="HAMP"
FT                   /evidence="ECO:0000259|PROSITE:PS50885"
FT   DOMAIN          614..664
FT                   /note="HAMP"
FT                   /evidence="ECO:0000259|PROSITE:PS50885"
FT   DOMAIN          669..884
FT                   /note="Methyl-accepting transducer"
FT                   /evidence="ECO:0000259|PROSITE:PS50111"
FT   REGION          673..720
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          855..893
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        674..720
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   962 AA;  103342 MW;  693988CB34EC4ECA CRC64;
     MLQNMRIGLR LGLGFGLVVV LMVILGGISI NRMATLNTDL DMVVKDRWPK AETTFGISSQ
     INVVARALRN AILLDDPAEV QKEIARINEA SVSVSKSMDE LSKSITSEEG KAKLKAVEAS
     RAAYREDLLK LVEYIRAGNK SAAQKMLFGS YRERQRSYFD AVDGLTQYQA KLLAVSGKEA
     EQTFVSSRNI IVALLVLSAL LACACAWLVT RSITRPIGAC MAAAGRIASG DTDVTLDVTA
     RDETGLLQVE MQKMVEAIRA LIADADMLSR AAVEGRLATR ADAAKHQGDF RKIVSGVNDT
     LDAVITPLNV AADYVDRISR GDIPPRITDT YNGDFNEVKN NLNRCIDALN GLLSDMNEMS
     KMHDLGDIDV VMPADNYQGA YRIMAKGVND MVNGHISVKK KAMACVAEFG KGNFDAELEK
     FPGKKAFIND TIEAVRSNIK NFIADMGHMS QQHDLGDIDV KMPEDQYQGA FQVMAKGVNN
     MVGGHISVKK KAMACVAEFG KGNFNADLEK FPGKKAFINE TIEGVRTNLK SFEEQLGILI
     TAAADGQLDK RANADLFVGG WNQLARGVND TITNIVEPLM VTADYVDRIS KGDMPPLITK
     EYRGQYNIIK QNLNTLIDAT NGIVAAAKEV AGGNLMVELR ERSAKDELMQ ALSAMVKKLS
     EVVAEVKSAA NNVAAGSREM SSGSEQMSQG ATEQAAAAEE ASSSMEEMSS NIRQNADNAS
     QTERIAIKSA QDARDGGKAV AETVTAMKDI ASKISIIEEI ARQTNLLALN AAIEAARAGE
     HGKGFAVVAA EVRKLAERSQ KAAGEISDLS ASSVEVAEKA GEMLGRIVPD IQKTAELVQE
     ISAASKEQDT GAEQINRAIQ QLDQVIQQNA SAAEEMASTA EELSAQSEQL QSIISFFRVD
     SSAQSSSAIA AAKPAAKKPA LAHAPANGYH KANQAPAKKV AHAGLNLNLE GGDHLDSEFE
     TF
//