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Q74DK5 (G6PI_GEOSL) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 64. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glucose-6-phosphate isomerase

Short name=GPI
EC=5.3.1.9
Alternative name(s):
Phosphoglucose isomerase
Short name=PGI
Phosphohexose isomerase
Short name=PHI
Gene names
Name:pgi
Ordered Locus Names:GSU1311
OrganismGeobacter sulfurreducens (strain ATCC 51573 / DSM 12127 / PCA) [Reference proteome] [HAMAP]
Taxonomic identifier243231 [NCBI]
Taxonomic lineageBacteriaProteobacteriaDeltaproteobacteriaDesulfuromonadalesGeobacteraceaeGeobacter

Protein attributes

Sequence length529 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-glucose 6-phosphate = D-fructose 6-phosphate. HAMAP-Rule MF_00473

Pathway

Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4. HAMAP-Rule MF_00473

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00473.

Sequence similarities

Belongs to the GPI family.

Ontologies

Keywords
   Biological processGluconeogenesis
Glycolysis
   Cellular componentCytoplasm
   Molecular functionIsomerase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processgluconeogenesis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

glycolysis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionglucose-6-phosphate isomerase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 529529Glucose-6-phosphate isomerase HAMAP-Rule MF_00473
PRO_0000180647

Sites

Active site3231Proton donor By similarity
Active site3521 By similarity
Active site4561 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q74DK5 [UniParc].

Last modified July 5, 2004. Version 1.
Checksum: 5D0B984F4A2316CD

FASTA52957,259
        10         20         30         40         50         60 
MNAHELWQRY QTYLLFDADT GLILDVSRMA FSDDFFASME PAMQRAFDAM ERLEAGEIAN 

        70         80         90        100        110        120 
PDENRMVGHY WLRSPELAPD PAIAAAIRET VDRVTAFAAD VHNGVVTAPR ARLFRNVLVI 

       130        140        150        160        170        180 
GIGGSALGPQ FVADALGGHG DRMRPFFFDN TDPDGMDRVL ETLGADGLAE TLAIVISKSG 

       190        200        210        220        230        240 
GTKETRNGML EAEAAYRRAG LDFSRHAVAV TGAGSELDRT AEAGGWLCRF PMWDWVGGRT 

       250        260        270        280        290        300 
SETSAVGLLP AALQGIPIRD FLDGARTCDT LTRRRETLRN PAALLALMWH HATRGSGSRD 

       310        320        330        340        350        360 
MVVLPYKDRL LLFSRYLQQL IMESIGKELD LDGTVVNQGL TVYGNKGSTD QHAYVQQLRE 

       370        380        390        400        410        420 
GTNNFFVAFI EVLKDREGAS LAVEPGFTSG DYLSGFLQGT RTALSEKGRE SLTITIPAIT 

       430        440        450        460        470        480 
PRTVGVLVAL FERAVGLYAS LVNINAYHQP GVEAGKKAAG GVLALTGEAL AFLRREGGTL 

       490        500        510        520 
SATEIAAALG RPEEAETIFR SLLHAAANPD HGVVMEAASP LTRSRFSAR 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE017180 Genomic DNA. Translation: AAR34687.1.
RefSeqNP_952364.1. NC_002939.5.

3D structure databases

ProteinModelPortalQ74DK5.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING243231.GSU1311.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAR34687; AAR34687; GSU1311.
GeneID2686480.
KEGGgsu:GSU1311.
PATRIC22025397. VBIGeoSul17553_1308.

Phylogenomic databases

eggNOGCOG0166.
HOGENOMHOG000131425.
KOK01810.
OMASPAACKT.
OrthoDBEOG64R61J.
ProtClustDBPRK14096.

Enzyme and pathway databases

BioCycGSUL243231:GH27-1320-MONOMER.
UniPathwayUPA00109; UER00181.

Family and domain databases

HAMAPMF_00473. G6P_isomerase.
InterProIPR001672. G6P_Isomerase.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERPTHR11469. PTHR11469. 1 hit.
PfamPF00342. PGI. 1 hit.
[Graphical view]
PRINTSPR00662. G6PISOMERASE.
PROSITEPS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG6PI_GEOSL
AccessionPrimary (citable) accession number: Q74DK5
Entry history
Integrated into UniProtKB/Swiss-Prot: March 29, 2005
Last sequence update: July 5, 2004
Last modified: February 19, 2014
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways