ID   Q74A12_GEOSL            Unreviewed;       543 AA.
AC   Q74A12;
DT   05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2004, sequence version 1.
DT   27-MAR-2024, entry version 101.
DE   SubName: Full=Methyl-accepting chemotaxis sensory transducer, class 40H {ECO:0000313|EMBL:AAR35952.1};
GN   Name=mcp40H-14 {ECO:0000313|EMBL:AAR35952.1};
GN   OrderedLocusNames=GSU2579 {ECO:0000313|EMBL:AAR35952.1};
OS   Geobacter sulfurreducens (strain ATCC 51573 / DSM 12127 / PCA).
OC   Bacteria; Thermodesulfobacteriota; Desulfuromonadia; Geobacterales;
OC   Geobacteraceae; Geobacter.
OX   NCBI_TaxID=243231 {ECO:0000313|EMBL:AAR35952.1, ECO:0000313|Proteomes:UP000000577};
RN   [1] {ECO:0000313|EMBL:AAR35952.1, ECO:0000313|Proteomes:UP000000577}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51573 / DSM 12127 / PCA
RC   {ECO:0000313|Proteomes:UP000000577};
RX   PubMed=14671304; DOI=10.1126/science.1088727;
RA   Methe B.A., Nelson K.E., Eisen J.A., Paulsen I.T., Nelson W.,
RA   Heidelberg J.F., Wu D., Wu M., Ward N., Beanan M.J., Dodson R.J.,
RA   Madupu R., Brinkac L.M., Daugherty S.C., DeBoy R.T., Durkin A.S., Gwinn M.,
RA   Kolonay J.F., Sullivan S.A., Haft D.H., Selengut J., Davidsen T.M.,
RA   Zafar N., White O., Tran B., Romero C., Forberger H.A., Weidman J.,
RA   Khouri H., Feldblyum T.V., Utterback T.R., Van Aken S.E., Lovley D.R.,
RA   Fraser C.M.;
RT   "Genome of Geobacter sulfurreducens: metal reduction in subsurface
RT   environments.";
RL   Science 302:1967-1969(2003).
CC   -!- SIMILARITY: Belongs to the methyl-accepting chemotaxis (MCP) protein
CC       family. {ECO:0000256|ARBA:ARBA00029447}.
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DR   EMBL; AE017180; AAR35952.1; -; Genomic_DNA.
DR   RefSeq; NP_953625.1; NC_002939.5.
DR   RefSeq; WP_010943215.1; NC_002939.5.
DR   AlphaFoldDB; Q74A12; -.
DR   SMR; Q74A12; -.
DR   STRING; 243231.GSU2579; -.
DR   EnsemblBacteria; AAR35952; AAR35952; GSU2579.
DR   KEGG; gsu:GSU2579; -.
DR   PATRIC; fig|243231.5.peg.2611; -.
DR   eggNOG; COG0840; Bacteria.
DR   HOGENOM; CLU_000445_107_27_7; -.
DR   InParanoid; Q74A12; -.
DR   OrthoDB; 5396233at2; -.
DR   Proteomes; UP000000577; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW.
DR   CDD; cd06225; HAMP; 1.
DR   CDD; cd19411; MCP2201-like_sensor; 1.
DR   CDD; cd11386; MCP_signal; 1.
DR   Gene3D; 1.10.287.950; Methyl-accepting chemotaxis protein; 1.
DR   InterPro; IPR003660; HAMP_dom.
DR   InterPro; IPR024478; HlyB_4HB_MCP.
DR   InterPro; IPR004089; MCPsignal_dom.
DR   InterPro; IPR047347; YvaQ-like_sensor.
DR   PANTHER; PTHR32089:SF112; HEME-BASED AEROTACTIC TRANSDUCER HEMAT; 1.
DR   PANTHER; PTHR32089; METHYL-ACCEPTING CHEMOTAXIS PROTEIN MCPB; 1.
DR   Pfam; PF12729; 4HB_MCP_1; 1.
DR   Pfam; PF00672; HAMP; 1.
DR   Pfam; PF00015; MCPsignal; 1.
DR   SMART; SM00304; HAMP; 1.
DR   SMART; SM00283; MA; 1.
DR   SUPFAM; SSF58104; Methyl-accepting chemotaxis protein (MCP) signaling domain; 1.
DR   PROSITE; PS50111; CHEMOTAXIS_TRANSDUC_2; 1.
DR   PROSITE; PS50885; HAMP; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000577};
KW   Transducer {ECO:0000256|ARBA:ARBA00023224, ECO:0000256|PROSITE-
KW   ProRule:PRU00284}; Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        13..35
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        190..211
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          213..265
FT                   /note="HAMP"
FT                   /evidence="ECO:0000259|PROSITE:PS50885"
FT   DOMAIN          270..506
FT                   /note="Methyl-accepting transducer"
FT                   /evidence="ECO:0000259|PROSITE:PS50111"
SQ   SEQUENCE   543 AA;  58355 MW;  C902ABB7F3859FD4 CRC64;
     MQWLRNLRVG IKLVAAFSVV AAIAAVVGFI GSVEIRRIQS DDRRLYEKIT VPMHDLAEMS
     VAFQRVRINL RDAVEATDPA EQALYLDTIR KLREVITEHQ DNFEKTILTD EGRTLFNEYK
     EARKVYGGYI DNIMQLNSAK KVTEAKALLH GDAKKAALHY QELLSKLVDA KQAQAKLTAE
     RNEHVASTSF TVMAVLSAVG VILAIGLGLL ISRMITTPLS RAVDVANRLA DGDLTVVVAA
     TSTDETGRLL TAMQNMVRSL REMVTQTATI SAGIASASSQ LHATSEQIAT GTEEVASQAG
     TVATASEEMS ATSQDIATNC HAAAGSAEQV AATTRQGFDV VRHTVDGIRD RGEKTRQNAQ
     IVASLGDRSE QIGDIVGTIE DIADQTNLLA LNAAIEAARA GEQGRGFAVV ADEVRALAER
     TTRATKEIGE MIRAIQQETK TAIVSMEEGV RGTERGAIEA AQLETALQQI LNQVNEVSMQ
     VGQIATAAEE QTATTGEVTS NIQQITEVVH QTAQGAEETA DAAAQLARQA QDLQALIGRF
     RLA
//