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Protein

Cell division protein FtsZ

Gene

ftsZ

Organism
Geobacter sulfurreducens (strain ATCC 51573 / DSM 12127 / PCA)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei139GTPUniRule annotation1
Binding sitei143GTPUniRule annotation1
Binding sitei187GTPUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi108 – 110GTPUniRule annotation3

GO - Molecular functioni

  • GTPase activity Source: TIGR
  • GTP binding Source: GO_Central

GO - Biological processi

Keywordsi

Biological processCell cycle, Cell division, SeptationUniRule annotation
LigandGTP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Cell division protein FtsZUniRule annotation
Gene namesi
Name:ftsZUniRule annotationImported
Ordered Locus Names:GSU3063Imported
OrganismiGeobacter sulfurreducens (strain ATCC 51573 / DSM 12127 / PCA)Imported
Taxonomic identifieri243231 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaDesulfuromonadalesGeobacteraceaeGeobacter
Proteomesi
  • UP000000577 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi243231.GSU3063.

Structurei

3D structure databases

ProteinModelPortaliQ748E1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini13 – 205TubulinInterPro annotationAdd BLAST193
Domaini207 – 325Tubulin_CInterPro annotationAdd BLAST119

Sequence similaritiesi

Belongs to the FtsZ family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CDK. Bacteria.
COG0206. LUCA.
HOGENOMiHOG000049094.
InParanoidiQ748E1.
KOiK03531.
OMAiMRAVKGI.
OrthoDBiPOG091H02KK.

Family and domain databases

CDDicd02201. FtsZ_type1. 1 hit.
Gene3Di3.30.1330.20. 1 hit.
3.40.50.1440. 1 hit.
HAMAPiMF_00909. FtsZ. 1 hit.
InterProiView protein in InterPro
IPR000158. Cell_div_FtsZ.
IPR020805. Cell_div_FtsZ_CS.
IPR024757. FtsZ_C.
IPR008280. Tub_FtsZ_C.
IPR018316. Tubulin/FtsZ_2-layer-sand-dom.
IPR037103. Tubulin/FtsZ_C_sf.
IPR036525. Tubulin/FtsZ_GTPase_sf.
IPR003008. Tubulin_FtsZ_GTPase.
PfamiView protein in Pfam
PF12327. FtsZ_C. 1 hit.
PF00091. Tubulin. 1 hit.
PRINTSiPR00423. CELLDVISFTSZ.
SMARTiView protein in SMART
SM00864. Tubulin. 1 hit.
SM00865. Tubulin_C. 1 hit.
SUPFAMiSSF52490. SSF52490. 1 hit.
SSF55307. SSF55307. 1 hit.
TIGRFAMsiTIGR00065. ftsZ. 1 hit.
PROSITEiView protein in PROSITE
PS01134. FTSZ_1. 1 hit.
PS01135. FTSZ_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q748E1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFEFDESIDQ CAKIKVVGVG GSGGNAVNTM IDSQVGGVDF LVANTDVQAL
60 70 80 90 100
RISKAPTKIQ IGRQLTKGLG AGADPSKGRE AALEDREQVA ELLKGADMIF
110 120 130 140 150
VAAGMGGGTG TGAAPVIAEV AKEVGALTVG VVTKPFSREG KQRLSKADEG
160 170 180 190 200
IRELKKHVDS LIVIPNDRLI GLAGKSMSII DAFKPADDVL RQAVQGISDL
210 220 230 240 250
ITTSGFINVD FADVKAIMSE RGMAMMGIGI ASGENRAVEA ALRAISSPLL
260 270 280 290 300
EEVDISGAKG VLVNIAGSSS MTMDEFEAVN RSIHEKVHED ANIIIGVSID
310 320 330 340 350
ETLGDQLKVT AIATGFGDRF DMEKARQELK NVTPFGKAEV NRDIPTFVRN
360 370 380
QQTRESSLSR QKAFFIDDED QYDIPTFLRK SVD
Length:383
Mass (Da):40,756
Last modified:July 5, 2004 - v1
Checksum:i99CBB95263C42003
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017180 Genomic DNA. Translation: AAR36455.1.
RefSeqiNP_954105.1. NC_002939.5.
WP_010943688.1. NC_002939.5.

Genome annotation databases

EnsemblBacteriaiAAR36455; AAR36455; GSU3063.
GeneIDi2686334.
KEGGigsu:GSU3063.
PATRICifig|243231.5.peg.3086.

Similar proteinsi

Entry informationi

Entry nameiQ748E1_GEOSL
AccessioniPrimary (citable) accession number: Q748E1
Entry historyiIntegrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: October 25, 2017
This is version 106 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.UniRule annotation

Keywords - Technical termi

Complete proteome, Reference proteomeImported