Q747K8 (GLGA2_GEOSL) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Glycogen synthase 2
EC=2.4.1.21

Alternative name(s):
Starch [bacterial glycogen] synthase 2

Gene names

Name:	glgA2
Synonyms:	glgA-2
Ordered Locus Names:	GSU3257

Organism

Geobacter sulfurreducens (strain ATCC 51573 / DSM 12127 / PCA) [Reference proteome] [HAMAP]

Taxonomic identifier

243231 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › delta/epsilon subdivisions › Deltaproteobacteria › Desulfuromonadales › Geobacteraceae › Geobacter › Geobacter sulfurreducens

Protein attributes

Sequence length	484 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Synthesizes alpha-1,4-glucan chains using ADP-glucose By similarity. HAMAP-Rule MF_00484
Catalytic activity	ADP-glucose + (1,4-alpha-D-glucosyl)(n) = ADP + (1,4-alpha-D-glucosyl)(n+1). HAMAP-Rule MF_00484
Pathway	Glycan biosynthesis; glycogen biosynthesis. HAMAP-Rule MF_00484
Sequence similarities	Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.

Ontologies

Keywords
Biological process	Glycogen biosynthesis
Molecular function	Glycosyltransferase Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	glycogen biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular_function	starch synthase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 484	484	Glycogen synthase 2 HAMAP-Rule MF_00484		PRO_0000188618
Sites
	Binding site	15	1	ADP-glucose By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q747K8 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: B06056E2B64EFBE5	FASTA	484	54,142
	10 20 30 40 50 60 MKVLMVASEV APFARTGGLA EVTAALPAAL RRMGHDVRVI MPFYRCAAQT ELGVRKARKS 70 80 90 100 110 120 AEVSLNGETH KGFLRQAALG DVPVYLVENR EFFSRDYLYG TPEGDYPDNP RRFAFFCRSV 130 140 150 160 170 180 LQFLKRMDFR PDVIHCHDWQ TALIPIILRL EAADDPFFAR TATVFTIHNL AYQGLFPAPA 190 200 210 220 230 240 IAETGLPSAL FTTEWLEYYG QLNLMKGAIL TADLITTVSE TYRREIMTPT QGCGLEGVLA 250 260 270 280 290 300 RRGDDLFGIV NGIDTDEWNP AADKRIFRNY SARALAGKAA DKLELQRELG MPAAPSVPLI 310 320 330 340 350 360 GMVSRLAEQK GIDLVLELLP RLAESELQFV LLGTGNACYL ERLNSFRSKG AANISINLGF 370 380 390 400 410 420 NDPLAPKIYA GSDLFLMPSR FEPCGLSQLI AMRYGTVPVV RHTGGLRDTV VDVTRHPREG 430 440 450 460 470 480 TGFTFEDFTA DACWEAIERA LAGYRDRESW RRIMRRGMHR DVSWHNAAGR YETLYRMAAD TRRG

References

[1]

"Genome of Geobacter sulfurreducens: metal reduction in subsurface environments." Methe B.A., Nelson K.E., Eisen J.A., Paulsen I.T., Nelson W.C., Heidelberg J.F., Wu D., Wu M., Ward N.L., Beanan M.J., Dodson R.J., Madupu R., Brinkac L.M., Daugherty S.C., DeBoy R.T., Durkin A.S., Gwinn M.L., Kolonay J.F. , Sullivan S.A., Haft D.H., Selengut J., Davidsen T.M., Zafar N., White O., Tran B., Romero C., Forberger H.A., Weidman J.F., Khouri H.M., Feldblyum T.V., Utterback T.R., Van Aken S.E., Lovley D.R., Fraser C.M. Science 302:1967-1969(2003) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 51573 / DSM 12127 / PCA.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE017180 Genomic DNA. Translation: AAR36648.1.
RefSeq	NP_954298.1. NC_002939.5.
3D structure databases
ProteinModelPortal	Q747K8.
ModBase	Search...
Protein-protein interaction databases
STRING	243231.GSU3257.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAR36648; AAR36648; GSU3257.
GeneID	2685785.
KEGG	gsu:GSU3257.
PATRIC	22029355. VBIGeoSul17553_3274.
Phylogenomic databases
eggNOG	COG0297.
HOGENOM	HOG000294940.
KO	K00703.
OMA	DEWNPAA.
ProtClustDB	CLSK829188.
Enzyme and pathway databases
BioCyc	GSUL243231:GH27-3296-MONOMER.
UniPathway	UPA00164.
Family and domain databases
HAMAP	MF_00484. Glycogen_synth.
InterPro	IPR001296. Glyco_trans_1. IPR011835. Glycogen/starch_synth. IPR013534. Starch_synth_cat_dom. [Graphical view]
Pfam	PF08323. Glyco_transf_5. 1 hit. PF00534. Glycos_transf_1. 1 hit. [Graphical view]
TIGRFAMs	TIGR02095. glgA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

GLGA2_GEOSL

Accession

Primary (citable) accession number: Q747K8

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 15, 2005
Last sequence update:	July 5, 2004
Last modified:	May 29, 2013
This is version 58 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program