Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Cytochrome P450

Gene

TT_P0059

Organism
Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi336 – 3361Iron (heme axial ligand)Combined sources

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

MonooxygenaseUniRule annotation, Oxidoreductase

Keywords - Ligandi

HemeUniRule annotationCombined sources, Iron, Metal-binding

Enzyme and pathway databases

BioCyciTTHE262724:GCAT-2094-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Cytochrome P450Imported
Gene namesi
Ordered Locus Names:TT_P0059Imported
Encoded oniPlasmid pTT27Imported
OrganismiThermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039)Imported
Taxonomic identifieri262724 [NCBI]
Taxonomic lineageiBacteriaDeinococcus-ThermusDeinococciThermalesThermaceaeThermus
Proteomesi
  • UP000000592 Componenti: Plasmid pTT27

Interactioni

Protein-protein interaction databases

STRINGi262724.TT_P0059.

Chemistry

BindingDBiQ746J6.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1N97X-ray1.80A/B1-389[»]
ProteinModelPortaliQ746J6.
SMRiQ746J6. Positions 1-385.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ746J6.

Family & Domainsi

Sequence similaritiesi

Belongs to the cytochrome P450 family.UniRule annotation

Phylogenomic databases

eggNOGiCOG2124. LUCA.
HOGENOMiHOG000136829.
OMAiHAPMEAI.
OrthoDBiEOG699746.

Family and domain databases

Gene3Di1.10.630.10. 1 hit.
InterProiIPR001128. Cyt_P450.
IPR017972. Cyt_P450_CS.
IPR002401. Cyt_P450_E_grp-I.
[Graphical view]
PfamiPF00067. p450. 1 hit.
[Graphical view]
PRINTSiPR00463. EP450I.
PR00385. P450.
SUPFAMiSSF48264. SSF48264. 1 hit.
PROSITEiPS00086. CYTOCHROME_P450. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q746J6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKRLSLREAW PYLKDLQQDP LAVLLAWGRA HPRLFLPLPR FPLALIFDPE
60 70 80 90 100
GVEGALLAEG TTKATFQYRA LSRLTGRGLL TDWGESWKEA RKALKDPFLP
110 120 130 140 150
KNVRGYREAM EEEARAFFGE WRGEERDLDH EMLALSLRLL GRALFGKPLS
160 170 180 190 200
PSLAEHALKA LDRIMAQTRS PLALLDLAAE ARFRKDRGAL YREAEALIVH
210 220 230 240 250
PPLSHLPRER ALSEAVTLLV AGHETVASAL TWSFLLLSHR PDWQKRVAES
260 270 280 290 300
EEAALAAFQE ALRLYPPAWI LTRRLERPLL LGEDRLPPGT TLVLSPYVTQ
310 320 330 340 350
RLHFPDGEAF RPERFLEERG TPSGRYFPFG LGQRLCLGRD FALLEGPIVL
360 370 380
RAFFRRFRLD PLPFPRVLAQ VTLRPEGGLP ARPREEVRA
Length:389
Mass (Da):44,256
Last modified:July 5, 2004 - v1
Checksum:i1D916BDAD5A30998
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017222 Genomic DNA. Translation: AAS82389.1.
RefSeqiWP_011174500.1. NC_005838.1.

Genome annotation databases

EnsemblBacteriaiAAS82389; AAS82389; TT_P0059.
KEGGitth:TT_P0059.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017222 Genomic DNA. Translation: AAS82389.1.
RefSeqiWP_011174500.1. NC_005838.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1N97X-ray1.80A/B1-389[»]
ProteinModelPortaliQ746J6.
SMRiQ746J6. Positions 1-385.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi262724.TT_P0059.

Chemistry

BindingDBiQ746J6.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAS82389; AAS82389; TT_P0059.
KEGGitth:TT_P0059.

Phylogenomic databases

eggNOGiCOG2124. LUCA.
HOGENOMiHOG000136829.
OMAiHAPMEAI.
OrthoDBiEOG699746.

Enzyme and pathway databases

BioCyciTTHE262724:GCAT-2094-MONOMER.

Miscellaneous databases

EvolutionaryTraceiQ746J6.

Family and domain databases

Gene3Di1.10.630.10. 1 hit.
InterProiIPR001128. Cyt_P450.
IPR017972. Cyt_P450_CS.
IPR002401. Cyt_P450_E_grp-I.
[Graphical view]
PfamiPF00067. p450. 1 hit.
[Graphical view]
PRINTSiPR00463. EP450I.
PR00385. P450.
SUPFAMiSSF48264. SSF48264. 1 hit.
PROSITEiPS00086. CYTOCHROME_P450. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Preliminary characterization and crystal structure of a thermostable cytochrome P450 from Thermus thermophilus."
    Yano J.K., Blasco F., Li H., Schmid R.D., Henne A., Poulos T.L.
    J. Biol. Chem. 278:608-616(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (1.80 ANGSTROMS) IN COMPLEX WITH HEME.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: HB27 / ATCC BAA-163 / DSM 7039Imported.

Entry informationi

Entry nameiQ746J6_THET2
AccessioniPrimary (citable) accession number: Q746J6
Entry historyi
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: March 16, 2016
This is version 90 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteomeImported, PlasmidImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.