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Protein

Protein Vpr

Gene

vpr

Organism
Human immunodeficiency virus 1
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

ActivatorSAAS annotation

Keywords - Biological processi

Cell cycleSAAS annotation, Host-virus interactionSAAS annotation, Transcription, Transcription regulationSAAS annotation, Viral penetration into host nucleusSAAS annotation, Virus entry into host cell

Names & Taxonomyi

Protein namesi
Recommended name:
Protein VprSAAS annotation
Gene namesi
Name:vprImported
OrganismiHuman immunodeficiency virus 1Imported
Taxonomic identifieri11676 [NCBI]
Taxonomic lineageiVirusesRetro-transcribing virusesRetroviridaeOrthoretrovirinaeLentivirusPrimate lentivirus group
Virus hostiHomo sapiens (Human) [TaxID: 9606]

Subcellular locationi

  • Host nucleus SAAS annotation
  • Virion SAAS annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Host nucleusSAAS annotation, VirionSAAS annotation

Pathology & Biotechi

Keywords - Diseasei

AIDSSAAS annotation

Structurei

3D structure databases

ProteinModelPortaliQ74455.
SMRiQ74455. Positions 1-96.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Family and domain databases

InterProiIPR000012. RetroV_VpR/X.
[Graphical view]
PfamiPF00522. VPR. 1 hit.
[Graphical view]
PRINTSiPR00444. HIVVPRVPX.

Sequencei

Sequence statusi: Complete.

Q74455-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MERAPEDQGP QREPSNEWTL ELLEELKHEA VRHFPRPWLH GLGQHIYETY
60 70 80 90
GDTWEGVKAI IRILQQLLFV HFRIGCQHSR IGIIQGRRGR NGAGRS
Length:96
Mass (Da):11,206
Last modified:November 1, 1996 - v1
Checksum:iBEFABD5F87FF0D96
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L39106 Genomic RNA. Translation: AAB51139.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L39106 Genomic RNA. Translation: AAB51139.1.

3D structure databases

ProteinModelPortaliQ74455.
SMRiQ74455. Positions 1-96.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

InterProiIPR000012. RetroV_VpR/X.
[Graphical view]
PfamiPF00522. VPR. 1 hit.
[Graphical view]
PRINTSiPR00444. HIVVPRVPX.
ProtoNetiSearch...

Publicationsi

  1. "Sequence analysis of the glycoprotein 120 coding region of a new HIV type 1 subtype A strain (HIV-1IbNg) from Nigeria."
    Howard T.M., Olaylele D.O., Rasheed S.
    AIDS Res. Hum. Retroviruses 10:1755-1757(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: IbNgImported.
  2. "Molecular characterization of the gp120 encoding region of a new subtype A strain of HIV-1 (HIV-1IbNg) from Nigeria."
    Howard T.M., Olaleye D.O., Rasheed S.
    Biokemistri 5:61-74(1995)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: IbNgImported.
  3. "Genomic structure and nucleotide sequence analysis of a new HIV type 1 subtype A strain from Nigeria."
    Howard T.M., Rasheed S.
    AIDS Res. Hum. Retroviruses 12:1413-1425(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: IbNgImported.
  4. "Biological characterization of a new subtype-A variant of human immunodeficiency virus type 1 from Nigeria."
    Olaleye D.O., Sheng Z., Howard T.M., Rasheed S.
    Biokemistri 5:51-59(1996)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: IbNgImported.
  5. "Isolation and characterization of a new subtype A variant of human immunodeficiency virus type I from Nigeria."
    Olaleye D.O., Sheng Z., Howard T.M., Rasheed S.
    Trop. Med. Int. Health 1:97-106(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: IbNgImported.

Entry informationi

Entry nameiQ74455_9HIV1
AccessioniPrimary (citable) accession number: Q74455
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: May 11, 2016
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.