Skip Header

Contribute Send feedback
Read comments (?) or add your own

Q741B5 (TAL_MYCPA) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 53. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Transaldolase
EC=2.2.1.2
Gene names
Name:tal
Ordered Locus Names:MAP_1177c
OrganismMycobacterium paratuberculosis [Complete proteome] [HAMAP]
Taxonomic identifier1770 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium › Mycobacterium avium complex (MAC)

Protein attributes

Sequence length373 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway By similarity. HAMAP MF_00493

Catalytic activity

Sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-erythrose 4-phosphate + D-fructose 6-phosphate. HAMAP MF_00493

Pathway

Carbohydrate degradation; pentose phosphate pathway; D-glyceraldehyde 3-phosphate and beta-D-fructose 6-phosphate from D-ribose 5-phosphate and D-xylulose 5-phosphate (non-oxidative stage): step 2/3. HAMAP MF_00493

Subcellular location

Cytoplasm By similarity HAMAP MF_00493.

Sequence similarities

Belongs to the transaldolase family. Type 2 subfamily.

Ontologies

Keywords
   Biological processPentose shunt
   Cellular componentCytoplasm
   Molecular functionTransferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processpentose-phosphate shunt

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionsedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 373373Transaldolase HAMAP MF_00493
PRO_1000126269

Sites

Active site1431 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q741B5 [UniParc].

Last modified July 5, 2004. Version 1.
Checksum: 93F07F4D17BD3BC3

FASTA37340,338
        10         20         30         40         50         60 
MTAQNPNLAA LSAAGVSVWL DDLSRDRLRS GNLQELIDTK CVVGVTTNPS IFQKAFAEGH 

        70         80         90        100        110        120 
AYDSQIAELA ARGADVDATI RTVTTDDVRN ACDVLTREWE NSDGVDGRVS IEVDPRLAGD 

       130        140        150        160        170        180 
TDKTIAQAVE LWKIVDRPNL FIKIPATQAG LPAITAVLAE GISVNVTLIF SVERYRAVMD 

       190        200        210        220        230        240 
AYLAGMEKAR EAGHDLSKIH SVASFFVSRV DTEIDKRLEK IGGERALALR GQAGVANARL 

       250        260        270        280        290        300 
AYAAYQEVFE GGQRYQALKA DGARVQRPLW ASTGVKNPDY SDTLYVTELV APNTVNTMPE 

       310        320        330        340        350        360 
KTIDAVADHG VIRGDTVTGT GPDAQRVFDE LAAVGVDLPD VFVVLENEGV EKFVDSWTEL 

       370 
MEETQKQLGS ASK

« Hide

References

[1]"The complete genome sequence of Mycobacterium avium subspecies paratuberculosis."
Li L., Bannantine J.P., Zhang Q., Amonsin A., May B.J., Alt D., Banerji N., Kanjilal S., Kapur V.
Proc. Natl. Acad. Sci. U.S.A. 102:12344-12349(2005) [PubMed: 16116077] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC BAA-968 / K-10.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE016958 Genomic DNA. Translation: AAS03494.1.
RefSeqNP_960111.1. NC_002944.2.

3D structure databases

HSSPHSSP built from PDB template 1VPX based on UniProtKB Q9WYD1.
ProteinModelPortalQ741B5.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBMYCT00000038008; EBMYCP00000036397; EBMYCG00000038003.
GeneID2719529.
GenomeReviewsGene locus MAP_1177c in contig AE016958_GR.
KEGGmpa:MAP1177c.
NMPDRfig|262316.1.peg.1177.
PATRIC17994815. VBIMycAvi108102_1238.

Organism-specific databases

CMRSearch...

Phylogenomic databases

GeneTreeEBGT00050000017406.
HOGENOMHBG321149.
OMAMPEKTLD.
ProtClustDBPRK03343.

Family and domain databases

HAMAPMF_00493. Transaldolase_2.
[Tree]
InterProIPR013785. Aldolase_TIM.
IPR001585. Transaldolase.
IPR004732. Transaldolase_2.
IPR018225. Transaldolase_AS.
[Graphical view]
Gene3DG3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KOK00616.
PANTHERPTHR10683. Transaldolase. 1 hit.
PfamPF00923. Transaldolase. 1 hit.
[Graphical view]
PIRSFPIRSF036915. Trnald_Bac_Plnt. 1 hit.
TIGRFAMsTIGR00876. Tal_mycobact. 1 hit.
PROSITEPS01054. TRANSALDOLASE_1. 1 hit.
PS00958. TRANSALDOLASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameTAL_MYCPA
AccessionPrimary (citable) accession number: Q741B5
Entry history
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: July 5, 2004
Last modified: January 25, 2012
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents