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Q73YM3 (COX3_MYCPA) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 75. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable cytochrome c oxidase subunit 3

EC=1.9.3.1
Alternative name(s):
Cytochrome aa3 subunit 3
Cytochrome c oxidase polypeptide III
Gene names
Name:ctaE
Ordered Locus Names:MAP_1932
OrganismMycobacterium paratuberculosis (strain ATCC BAA-968 / K-10) [Complete proteome] [HAMAP]
Taxonomic identifier262316 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacteriumMycobacterium avium complex (MAC)

Protein attributes

Sequence length203 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

Subcellular location

Cell membrane; Multi-pass membrane protein By similarity.

Sequence similarities

Belongs to the cytochrome c oxidase subunit 3 family.

Ontologies

Keywords
   Cellular componentCell membrane
Membrane
   DomainTransmembrane
Transmembrane helix
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processaerobic electron transport chain

Inferred from electronic annotation. Source: InterPro

   Cellular_componentintegral component of membrane

Inferred from electronic annotation. Source: UniProtKB-KW

plasma membrane

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functioncytochrome-c oxidase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 203203Probable cytochrome c oxidase subunit 3
PRO_0000183883

Regions

Transmembrane30 – 5021Helical; Potential
Transmembrane70 – 9021Helical; Potential
Transmembrane102 – 12221Helical; Potential
Transmembrane142 – 16221Helical; Potential
Transmembrane179 – 19921Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
Q73YM3 [UniParc].

Last modified July 5, 2004. Version 1.
Checksum: 1BBC9FD1064A6AD0

FASTA20322,434
        10         20         30         40         50         60 
MTSAVGTSGT AITSRVHSLN RPNMVSVGTI VWLSSELMFF AGLFAMYFTA RAQSGGKWPP 

        70         80         90        100        110        120 
PPTELNLYQA VPVTLVLIAS SFTCQMGVFA AERGDVFGLR RWYVITFLMG LFFVLGQGYE 

       130        140        150        160        170        180 
YYHLMGHGTT IPGSAYGSVF YLATGFHDLH VTGGLVAFIF LLARTAMSKF TPAQATASIV 

       190        200 
VSYYWHFVDI VWIALFTVIY FIR 

« Hide

References

[1]"The complete genome sequence of Mycobacterium avium subspecies paratuberculosis."
Li L., Bannantine J.P., Zhang Q., Amonsin A., May B.J., Alt D., Banerji N., Kanjilal S., Kapur V.
Proc. Natl. Acad. Sci. U.S.A. 102:12344-12349(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC BAA-968 / K-10.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE016958 Genomic DNA. Translation: AAS04249.1.
RefSeqNP_960866.1. NC_002944.2.

3D structure databases

ProteinModelPortalQ73YM3.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING262316.MAP1932.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAS04249; AAS04249; MAP_1932.
GeneID2720452.
KEGGmpa:MAP1932.
PATRIC17996444. VBIMycAvi108102_2049.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1845.
KOK02276.
OMAYEFHELL.
OrthoDBEOG6SFPBZ.
ProtClustDBCLSK872023.

Enzyme and pathway databases

BioCycMAVI262316:GCQR-1955-MONOMER.

Family and domain databases

Gene3D1.20.120.80. 1 hit.
InterProIPR024791. Cyt_c/ubiquinol_Oxase_su3.
IPR000298. Cyt_c_oxidase_su3.
IPR013833. Cyt_c_oxidase_su3_a-hlx.
[Graphical view]
PANTHERPTHR11403. PTHR11403. 1 hit.
PfamPF00510. COX3. 1 hit.
[Graphical view]
SUPFAMSSF81452. SSF81452. 1 hit.
PROSITEPS50253. COX3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCOX3_MYCPA
AccessionPrimary (citable) accession number: Q73YM3
Entry history
Integrated into UniProtKB/Swiss-Prot: April 26, 2005
Last sequence update: July 5, 2004
Last modified: April 16, 2014
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families