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Q73YL6

- COX4_MYCPA

UniProt

Q73YL6 - COX4_MYCPA

Protein

Probable cytochrome c oxidase polypeptide 4

Gene

ctaF

Organism
Mycobacterium paratuberculosis (strain ATCC BAA-968 / K-10)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 63 (01 Oct 2014)
      Sequence version 1 (05 Jul 2004)
      Previous versions | rss
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    Functioni

    Part of cytochrome c oxidase, its function is unknown.By similarity

    Catalytic activityi

    4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

    GO - Molecular functioni

    1. cytochrome-c oxidase activity Source: UniProtKB-EC

    Keywords - Molecular functioni

    Oxidoreductase

    Enzyme and pathway databases

    BioCyciMAVI262316:GCQR-1962-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable cytochrome c oxidase polypeptide 4 (EC:1.9.3.1)
    Alternative name(s):
    Cytochrome aa3 subunit 4
    Cytochrome c oxidase polypeptide IV
    Gene namesi
    Name:ctaF
    Ordered Locus Names:MAP_1939c
    OrganismiMycobacterium paratuberculosis (strain ATCC BAA-968 / K-10)
    Taxonomic identifieri262316 [NCBI]
    Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacteriumMycobacterium avium complex (MAC)
    ProteomesiUP000000580: Chromosome

    Subcellular locationi

    Cell membrane By similarity; Multi-pass membrane protein By similarity

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. plasma membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cell membrane, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 139139Probable cytochrome c oxidase polypeptide 4PRO_0000220018Add
    BLAST

    Interactioni

    Subunit structurei

    Associates with subunits I, II and III to form cytochrome c oxidase.By similarity

    Protein-protein interaction databases

    STRINGi262316.MAP1939c.

    Structurei

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei10 – 3021HelicalSequence AnalysisAdd
    BLAST
    Transmembranei36 – 5621HelicalSequence AnalysisAdd
    BLAST
    Transmembranei78 – 9821HelicalSequence AnalysisAdd
    BLAST
    Transmembranei101 – 12121HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiNOG07397.
    OMAiGTYFRFV.
    OrthoDBiEOG63FW2X.

    Family and domain databases

    InterProiIPR021050. Cyt_c_oxidase_su4_actinobac.
    [Graphical view]
    PfamiPF12270. Cyt_c_ox_IV. 1 hit.
    [Graphical view]
    PIRSFiPIRSF017385. CtaF. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q73YL6-1 [UniParc]FASTAAdd to Basket

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    MHIEARLFEF IAGFFFLTAL LYGVLTALFA TGGEEWAGTT ALALTGGLAL    50
    IVATFFRFVA RRIDTRPEDY EGAEISDGAG ELGFFSPHSW WPILIALSGS 100
    VAAVGIALWL PWLIVAGVMF ILSSVAGLVF EYYLGPEKH 139
    Length:139
    Mass (Da):15,076
    Last modified:July 5, 2004 - v1
    Checksum:i982FDD33F94C2CBA
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE016958 Genomic DNA. Translation: AAS04256.1.
    RefSeqiNP_960873.1. NC_002944.2.

    Genome annotation databases

    EnsemblBacteriaiAAS04256; AAS04256; MAP_1939c.
    GeneIDi2721327.
    KEGGimpa:MAP1939c.
    PATRICi17996458. VBIMycAvi108102_2056.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE016958 Genomic DNA. Translation: AAS04256.1 .
    RefSeqi NP_960873.1. NC_002944.2.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 262316.MAP1939c.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAS04256 ; AAS04256 ; MAP_1939c .
    GeneIDi 2721327.
    KEGGi mpa:MAP1939c.
    PATRICi 17996458. VBIMycAvi108102_2056.

    Phylogenomic databases

    eggNOGi NOG07397.
    OMAi GTYFRFV.
    OrthoDBi EOG63FW2X.

    Enzyme and pathway databases

    BioCyci MAVI262316:GCQR-1962-MONOMER.

    Family and domain databases

    InterProi IPR021050. Cyt_c_oxidase_su4_actinobac.
    [Graphical view ]
    Pfami PF12270. Cyt_c_ox_IV. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF017385. CtaF. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "The complete genome sequence of Mycobacterium avium subspecies paratuberculosis."
      Li L., Bannantine J.P., Zhang Q., Amonsin A., May B.J., Alt D., Banerji N., Kanjilal S., Kapur V.
      Proc. Natl. Acad. Sci. U.S.A. 102:12344-12349(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC BAA-968 / K-10.

    Entry informationi

    Entry nameiCOX4_MYCPA
    AccessioniPrimary (citable) accession number: Q73YL6
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 26, 2005
    Last sequence update: July 5, 2004
    Last modified: October 1, 2014
    This is version 63 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3