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Protein

Probable cytochrome c oxidase polypeptide 4

Gene

ctaF

Organism
Mycobacterium paratuberculosis (strain ATCC BAA-968 / K-10)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Part of cytochrome c oxidase, its function is unknown.By similarity

Catalytic activityi

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Names & Taxonomyi

Protein namesi
Recommended name:
Probable cytochrome c oxidase polypeptide 4 (EC:1.9.3.1)
Alternative name(s):
Cytochrome aa3 subunit 4
Cytochrome c oxidase polypeptide IV
Gene namesi
Name:ctaF
Ordered Locus Names:MAP_1939c
OrganismiMycobacterium paratuberculosis (strain ATCC BAA-968 / K-10)
Taxonomic identifieri262316 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacteriumMycobacterium avium complex (MAC)
Proteomesi
  • UP000000580 Componenti: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei10 – 30HelicalSequence analysisAdd BLAST21
Transmembranei36 – 56HelicalSequence analysisAdd BLAST21
Transmembranei78 – 98HelicalSequence analysisAdd BLAST21
Transmembranei101 – 121HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002200181 – 139Probable cytochrome c oxidase polypeptide 4Add BLAST139

Interactioni

Subunit structurei

Associates with subunits I, II and III to form cytochrome c oxidase.By similarity

Protein-protein interaction databases

STRINGi262316.MAP1939c.

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4108ZRS. Bacteria.
ENOG4111RHJ. LUCA.
OMAiGTYFRFV.
OrthoDBiPOG091H0B59.

Family and domain databases

InterProiIPR021050. Cyt_c_oxidase_su4_actinobac.
[Graphical view]
PfamiPF12270. Cyt_c_ox_IV. 1 hit.
[Graphical view]
PIRSFiPIRSF017385. CtaF. 1 hit.

Sequencei

Sequence statusi: Complete.

Q73YL6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHIEARLFEF IAGFFFLTAL LYGVLTALFA TGGEEWAGTT ALALTGGLAL
60 70 80 90 100
IVATFFRFVA RRIDTRPEDY EGAEISDGAG ELGFFSPHSW WPILIALSGS
110 120 130
VAAVGIALWL PWLIVAGVMF ILSSVAGLVF EYYLGPEKH
Length:139
Mass (Da):15,076
Last modified:July 5, 2004 - v1
Checksum:i982FDD33F94C2CBA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE016958 Genomic DNA. Translation: AAS04256.1.
RefSeqiWP_003872269.1. NC_002944.2.

Genome annotation databases

EnsemblBacteriaiAAS04256; AAS04256; MAP_1939c.
GeneIDi2721327.
KEGGimpa:MAP_1939c.
PATRICi17996458. VBIMycAvi108102_2056.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE016958 Genomic DNA. Translation: AAS04256.1.
RefSeqiWP_003872269.1. NC_002944.2.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi262316.MAP1939c.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAS04256; AAS04256; MAP_1939c.
GeneIDi2721327.
KEGGimpa:MAP_1939c.
PATRICi17996458. VBIMycAvi108102_2056.

Phylogenomic databases

eggNOGiENOG4108ZRS. Bacteria.
ENOG4111RHJ. LUCA.
OMAiGTYFRFV.
OrthoDBiPOG091H0B59.

Family and domain databases

InterProiIPR021050. Cyt_c_oxidase_su4_actinobac.
[Graphical view]
PfamiPF12270. Cyt_c_ox_IV. 1 hit.
[Graphical view]
PIRSFiPIRSF017385. CtaF. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiCOX4_MYCPA
AccessioniPrimary (citable) accession number: Q73YL6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 26, 2005
Last sequence update: July 5, 2004
Last modified: November 2, 2016
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.