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Q73YL6 (COX4_MYCPA) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 62. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable cytochrome c oxidase polypeptide 4

EC=1.9.3.1
Alternative name(s):
Cytochrome aa3 subunit 4
Cytochrome c oxidase polypeptide IV
Gene names
Name:ctaF
Ordered Locus Names:MAP_1939c
OrganismMycobacterium paratuberculosis (strain ATCC BAA-968 / K-10) [Complete proteome] [HAMAP]
Taxonomic identifier262316 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacteriumMycobacterium avium complex (MAC)

Protein attributes

Sequence length139 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Part of cytochrome c oxidase, its function is unknown By similarity.

Catalytic activity

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

Subunit structure

Associates with subunits I, II and III to form cytochrome c oxidase By similarity.

Subcellular location

Cell membrane; Multi-pass membrane protein By similarity.

Sequence similarities

Belongs to the cytochrome c oxidase bacterial subunit CtaF family.

Ontologies

Keywords
   Cellular componentCell membrane
Membrane
   DomainTransmembrane
Transmembrane helix
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Cellular_componentintegral component of membrane

Inferred from electronic annotation. Source: UniProtKB-KW

plasma membrane

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functioncytochrome-c oxidase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 139139Probable cytochrome c oxidase polypeptide 4
PRO_0000220018

Regions

Transmembrane10 – 3021Helical; Potential
Transmembrane36 – 5621Helical; Potential
Transmembrane78 – 9821Helical; Potential
Transmembrane101 – 12121Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
Q73YL6 [UniParc].

Last modified July 5, 2004. Version 1.
Checksum: 982FDD33F94C2CBA

FASTA13915,076
        10         20         30         40         50         60 
MHIEARLFEF IAGFFFLTAL LYGVLTALFA TGGEEWAGTT ALALTGGLAL IVATFFRFVA 

        70         80         90        100        110        120 
RRIDTRPEDY EGAEISDGAG ELGFFSPHSW WPILIALSGS VAAVGIALWL PWLIVAGVMF 

       130 
ILSSVAGLVF EYYLGPEKH 

« Hide

References

[1]"The complete genome sequence of Mycobacterium avium subspecies paratuberculosis."
Li L., Bannantine J.P., Zhang Q., Amonsin A., May B.J., Alt D., Banerji N., Kanjilal S., Kapur V.
Proc. Natl. Acad. Sci. U.S.A. 102:12344-12349(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC BAA-968 / K-10.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE016958 Genomic DNA. Translation: AAS04256.1.
RefSeqNP_960873.1. NC_002944.2.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING262316.MAP1939c.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAS04256; AAS04256; MAP_1939c.
GeneID2721327.
KEGGmpa:MAP1939c.
PATRIC17996458. VBIMycAvi108102_2056.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGNOG07397.
OMAGTYFRFV.
OrthoDBEOG63FW2X.

Enzyme and pathway databases

BioCycMAVI262316:GCQR-1962-MONOMER.

Family and domain databases

InterProIPR021050. Cyt_c_oxidase_su4_actinobac.
[Graphical view]
PfamPF12270. Cyt_c_ox_IV. 1 hit.
[Graphical view]
PIRSFPIRSF017385. CtaF. 1 hit.
ProtoNetSearch...

Entry information

Entry nameCOX4_MYCPA
AccessionPrimary (citable) accession number: Q73YL6
Entry history
Integrated into UniProtKB/Swiss-Prot: April 26, 2005
Last sequence update: July 5, 2004
Last modified: May 14, 2014
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families