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Q73X75 (GLGB_MYCPA) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 78. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
1,4-alpha-glucan branching enzyme GlgB

EC=2.4.1.18
Alternative name(s):
1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase
Alpha-(1->4)-glucan branching enzyme
Glycogen branching enzyme
Short name=BE
Gene names
Name:glgB
Ordered Locus Names:MAP_2434
OrganismMycobacterium paratuberculosis (strain ATCC BAA-968 / K-10) [Complete proteome] [HAMAP]
Taxonomic identifier262316 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacteriumMycobacterium avium complex (MAC)

Protein attributes

Sequence length731 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position By similarity. HAMAP-Rule MF_00685

Catalytic activity

Transfers a segment of a (1->4)-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain. HAMAP-Rule MF_00685

Pathway

Glycan biosynthesis; glycogen biosynthesis. HAMAP-Rule MF_00685

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00685

Sequence similarities

Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 7317311,4-alpha-glucan branching enzyme GlgB HAMAP-Rule MF_00685
PRO_0000188717

Sites

Active site4111Nucleophile By similarity
Active site4641Proton donor By similarity

Sequences

Sequence LengthMass (Da)Tools
Q73X75 [UniParc].

Last modified July 5, 2004. Version 1.
Checksum: ED7DEAD33683C636

FASTA73181,660
        10         20         30         40         50         60 
MSHADQLART HLAPDPADLS RLVAGTHHDP HGILGAHEYG DHTVIRAFRP HATEVAALVG 

        70         80         90        100        110        120 
GDRFAMQHIE SGLFAVALPF TNLIDYRLQI TYPDSEPYVV ADAYRFLPTL GEVDLHLFGE 

       130        140        150        160        170        180 
GRHERLWEVL GAHPRSFTTA DGVVTGVSFA VWAPNAKGIS LIGEFNGWTG TEAPMRVLGS 

       190        200        210        220        230        240 
SGVWELFWPD FPIGGLYKFK VHGADGVVTE RADPMAFATE VPPHTASRVT LSSYTWGDAD 

       250        260        270        280        290        300 
WMTQRAARNP VFEPMSTYEV HLGSWRPGLS YRQLARELTD YVVEHGFTHV ELLPVAEHPF 

       310        320        330        340        350        360 
AGSWGYQVTS YYAPTSRFGT PDEFRALVDA LHQAGIGVIV DWVPAHFPKD AWALGRFDGT 

       370        380        390        400        410        420 
PLYEHSDPKR GEQLDWGTYV FDFGRREVRN FLVANALYWL QEFHIDGLRV DAVASMLYLD 

       430        440        450        460        470        480 
YSRPEGGWTP NIYGGRENLE AVQFLQEMNA TAHKSAPGIV TIAEESTSWP GVTRPTNLGG 

       490        500        510        520        530        540 
LGFSMKWNMG WMHDTLDYIS RDPIYRSYHH HEMTFSMLYA FSENYVLPLS HDEVVHGKGT 

       550        560        570        580        590        600 
LWGRMPGNNH VKAAGLRSLL AYQWAHPGKQ LLFMGQEFGQ RAEWSEERGL DWWQLDEQGF 

       610        620        630        640        650        660 
SNGILRLVRD INDIYRSHPA LWSQDTVPDG YSWIDANDSA NNVLSFLRYG KDGSVMACVF 

       670        680        690        700        710        720 
NFAGAEHSGY RLGLPSAGRW REVLNTDATV YNGSGIGNMG GVDATEDPWH GRPASAVLVL 

       730 
PPTSALWLEP K 

« Hide

References

[1]"The complete genome sequence of Mycobacterium avium subspecies paratuberculosis."
Li L., Bannantine J.P., Zhang Q., Amonsin A., May B.J., Alt D., Banerji N., Kanjilal S., Kapur V.
Proc. Natl. Acad. Sci. U.S.A. 102:12344-12349(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC BAA-968 / K-10.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE016958 Genomic DNA. Translation: AAS04751.1.
RefSeqNP_961368.1. NC_002944.2.

3D structure databases

ProteinModelPortalQ73X75.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING262316.MAP2434.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAS04751; AAS04751; MAP_2434.
GeneID2720716.
KEGGmpa:MAP2434.
PATRIC17997534. VBIMycAvi108102_2585.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0296.
KOK00700.
OMAISEGRHE.
OrthoDBEOG6JX7GT.

Enzyme and pathway databases

BioCycMAVI262316:GCQR-2466-MONOMER.
UniPathwayUPA00164.

Family and domain databases

Gene3D2.60.40.10. 2 hits.
2.60.40.1180. 1 hit.
3.20.20.80. 1 hit.
HAMAPMF_00685. GlgB.
InterProIPR006048. A-amylase_b_C.
IPR006407. GlgB.
IPR015902. Glyco_hydro_13.
IPR013780. Glyco_hydro_13_b.
IPR006047. Glyco_hydro_13_cat_dom.
IPR004193. Glyco_hydro_13_N.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
[Graphical view]
PANTHERPTHR10357. PTHR10357. 1 hit.
PfamPF00128. Alpha-amylase. 1 hit.
PF02806. Alpha-amylase_C. 1 hit.
PF02922. CBM_48. 1 hit.
[Graphical view]
PIRSFPIRSF000463. GlgB. 1 hit.
SUPFAMSSF51445. SSF51445. 1 hit.
SSF81296. SSF81296. 2 hits.
TIGRFAMsTIGR01515. branching_enzym. 1 hit.
ProtoNetSearch...

Entry information

Entry nameGLGB_MYCPA
AccessionPrimary (citable) accession number: Q73X75
Entry history
Integrated into UniProtKB/Swiss-Prot: May 10, 2005
Last sequence update: July 5, 2004
Last modified: June 11, 2014
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries