Q73WR7 (Q73WR7_MYCPA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
RocA EMBL AAS04910.1

Gene names

Name:	rocA EMBL AAS04910.1
Ordered Locus Names:	MAP_2593c

Organism

Mycobacterium paratuberculosis [Complete proteome] [HAMAP]

Taxonomic identifier

1770 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium › Mycobacterium avium complex (MAC)

Protein attributes

Sequence length	546 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the aldehyde dehydrogenase family. RuleBase RU003345

Ontologies

Keywords
Molecular function	Oxidoreductase RuleBase RU003344
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	proline biosynthetic process Inferred from electronic annotation. Source: InterPro
Cellular component	mitochondrial matrix Inferred from electronic annotation. Source: InterPro
Molecular function	1-pyrroline-5-carboxylate dehydrogenase activity Inferred from electronic annotation. Source: InterPro oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q73WR7 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: 94BFBEBC7353680E	FASTA	546	58,959
	10 20 30 40 50 60 MDAITGISEV PVPANEPVHD YAPRSAERAR LRAELAALAG HPIDLPHVIG GRHRMGDGER 70 80 90 100 110 120 IDVVQPHRHA AKLGTLTNAV HADATAAVDA AMAAKSDWAA MPFDERAAVF LRAADLLAGP 130 140 150 160 170 180 WREKIAAATM LGQSKSAYQA EIDSPCEQID FWRFNVAFAR QILAQQPISG PGEWNRSDYR 190 200 210 220 230 240 PLDGFVYAIT PFNFTSIAGN LPTAPALMGN TVVWKPSITQ TLSAYLTMQL LEAAGLPPGV 250 260 270 280 290 300 INLVTGDGFA VSDVALADRR LAGIHFTGST ATFQRLWYQV GTNIGHYHCY PRLVGETGGK 310 320 330 340 350 360 DFIVAHASAR PDVLRTALIR GAFDYQGQKC SAASRAFIAQ SVWRRMGDEF LAETAALRYG 370 380 390 400 410 420 DVTDLTNFGG ALIDRRAFVK NVDAIERAKG APHVTLAVGG EYDDSEGYFV RPTVLLSDDP 430 440 450 460 470 480 ADESFATEYF GPLLSVHVYP DDDYQRILDV VDTGSRYALT GAVIADDRAA VLAAQDRLRF 490 500 510 520 530 540 AAGNFYVNDK PTGAVVGRQP FGGSRGSGTN DKAGSPLNLL RWTSARTIKE TFVPATDHTY PHMAAD

References

[1]

"The complete genome sequence of Mycobacterium avium subspecies paratuberculosis." Li L., Bannantine J.P., Zhang Q., Amonsin A., May B.J., Alt D., Banerji N., Kanjilal S., Kapur V. Proc. Natl. Acad. Sci. U.S.A. 102:12344-12349(2005) [PubMed: 16116077] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-968 / K-10.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE016958 Genomic DNA. Translation: AAS04910.1.
RefSeq	NP_961527.1. NC_002944.2.
3D structure databases
ProteinModelPortal	Q73WR7.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBMYCT00000037746; EBMYCP00000036135; EBMYCG00000037741.
GeneID	2721231.
GenomeReviews	Gene locus MAP_2593c in contig AE016958_GR.
KEGG	mpa:MAP2593c.
NMPDR	fig|262316.1.peg.2593.
PATRIC	17997880. VBIMycAvi108102_2754.
Organism-specific databases
CMR	Search...
Phylogenomic databases
GeneTree	EBGT00050000015660.
HOGENOM	HBG752218.
OMA	CELVDFW.
ProtClustDB	CLSK871904.
Family and domain databases
InterPro	IPR016161. Ald_DH/histidinol_DH. IPR016163. Ald_DH_C. IPR016160. Ald_DH_CS. IPR016162. Ald_DH_N. IPR015590. Aldehyde_DH_dom. IPR005931. Delta1-pyrroline-5-COlate_DH-1. [Graphical view]
Gene3D	G3DSA:3.40.309.10. Aldehyde_dehydrogenase_C. 1 hit. G3DSA:3.40.605.10. Aldehyde_dehydrogenase_N. 1 hit.
KO	K00294.
Pfam	PF00171. Aldedh. 1 hit. [Graphical view]
SUPFAM	SSF53720. Aldehyde_DH/Histidinol_DH. 1 hit.
TIGRFAMs	TIGR01236. D1pyr5carbox1. 1 hit.
PROSITE	PS00070. ALDEHYDE_DEHYDR_CYS. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q73WR7_MYCPA

Accession

Primary (citable) accession number: Q73WR7

Entry history

Integrated into UniProtKB/TrEMBL:	July 5, 2004
Last sequence update:	July 5, 2004
Last modified:	December 14, 2011
This is version 48 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)