Reviewed, UniProtKB/Swiss-Prot Q73VU0 (MQO_MYCPA)

Names and origin

Protein names

Recommended name:
    Probable malate:quinone oxidoreductase
    EC=1.1.99.16
Alternative name(s):
    Malate dehydrogenase [acceptor]
    MQO

Gene names

Name:	mqo
Ordered Locus Names:	MAP_2921c

Organism

Mycobacterium paratuberculosis [Complete proteome] [HAMAP]

Taxonomic identifier

1770 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium › Mycobacterium avium complex (MAC)

Protein attributes

Sequence length	501 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	(S)-malate + acceptor = oxaloacetate + reduced acceptor.
Cofactor	FAD By similarity.
Pathway	Carbohydrate metabolism; tricarboxylic acid cycle.
Sequence similarities	Belongs to the MQO family.

Ontologies

Keywords
Biological process	Tricarboxylic acid cycle
Ligand	FAD Flavoprotein
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW tricarboxylic acid cycle Inferred from electronic annotation. Source: HAMAP
Molecular function	malate dehydrogenase (acceptor) activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 501	501	Probable malate:quinone oxidoreductase		PRO_0000325500

Sequences

	Sequence		Length	Mass (Da)
	Q73VU0-1 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: A2BBF534427F4B5E	FASTA	501	54,937
	10 20 30 40 50 60 MSSLARTTRA DVVLVGAGIM SATLGALLRR LQPDWSMTFV ERLDAVAAES SSPWNNAGTG 70 80 90 100 110 120 HSALCELNYT PQRADGSIDI AKAVRINEQF QVTRQFWAYA VENGMLTDRG FVTPIPHASF 130 140 150 160 170 180 VRGARAVEYL RRRQQALAPN PLFAGIELIE DADEFARRLP LMADRRDFSE PTALNWARHG 190 200 210 220 230 240 TDVDFGALSR QLIGFCVRGG ATALFGHQVH NLTRESDGSW TLLIRNRRTG EKHWCNAKFV 250 260 270 280 290 300 LVGAGGDALP LLQKSGIGEA RGFAGFPIGG RFLRADNPVL TEAHRAKVYG APAPGAPPLG 310 320 330 340 350 360 ALHLDLRYVN GKPWLVFGPY AGWSPKFLKH GHFTDLPRSV RPHNLVALLG VGVTQLTLLR 370 380 390 400 410 420 YLIGQLRLSA PDRMRMLREF APTAVDSDWE LTVAGQRVQV IRRDRRRGGV LDFDTTVVAA 430 440 450 460 470 480 GDGSIAGLLG GSPGASTAVP IMLDVLQRCF ADRYRSWLPA LKEMVPSLGV TLSDEPALYE 490 500 EVYSWGTKIL GLDELDEERP K

References

[1]

"The complete genome sequence of Mycobacterium avium subspecies paratuberculosis." Li L., Bannantine J.P., Zhang Q., Amonsin A., May B.J., Alt D., Banerji N., Kanjilal S., Kapur V. Proc. Natl. Acad. Sci. U.S.A. 102:12344-12349(2005) [PubMed: 16116077] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-968 / K-10.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE016958 Genomic DNA. Translation: AAS05238.1.
RefSeq	NP_961855.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	2721811.
GenomeReviews	Gene locus MAP_2921c in contig AE016958_GR.
KEGG	mpa:MAP2921c.
NMPDR	fig|262316.1.peg.2921.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q73VU0.
Family and domain databases
HAMAP	MF_00212. [Tree]
InterPro	IPR006231. Malate_quinone_OxRdtase. [Graphical view]
Pfam	PF06039. Mqo. 1 hit. [Graphical view]
TIGRFAMs	TIGR01320. mal_quin_oxido. 1 hit.
ProtoNet	Search...

Entry information

Entry name

MQO_MYCPA

Accession

Primary (citable) accession number: Q73VU0

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 18, 2008
Last sequence update:	July 5, 2004
Last modified:	November 4, 2008
This is version 25 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)