Q73VS7 (Q73VS7_MYCPA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Methionine aminopeptidase RuleBase RU003653
EC=3.4.11.18 RuleBase RU003653

Gene names

Name:	map EMBL AAS05251.1
Ordered Locus Names:	MAP_2934c

Organism

Mycobacterium paratuberculosis [Complete proteome] [HAMAP]

Taxonomic identifier

1770 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium › Mycobacterium avium complex (MAC)

Protein attributes

Sequence length	285 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Removes the N-terminal methionine from nascent proteins By similarity. RuleBase RU003653
Catalytic activity	Release of N-terminal amino acids, preferentially methionine, from peptides and arylamides. RuleBase RU003653
Cofactor	Binds 2 cobalt ions per subunit By similarity. RuleBase RU003653
Sequence similarities	Belongs to the peptidase M24A family. RuleBase RU003653

Ontologies

Keywords
Ligand	Cobalt RuleBase RU003653 Metal-binding RuleBase RU003653
Molecular function	Aminopeptidase RuleBase RU003653 Hydrolase Protease
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	cellular process Inferred from electronic annotation. Source: InterPro proteolysis Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	aminopeptidase activity Inferred from electronic annotation. Source: UniProtKB-KW metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW metalloexopeptidase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q73VS7 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: 18AF23C4D3D6005E	FASTA	285	30,987
	10 20 30 40 50 60 MPARTALSPG ALSPTLPVPA RIPRPEYVGK PTAREGSEPW VQTPEVIEKM RVAGRIAAGA 70 80 90 100 110 120 LVEAGKAVAP GVTTDELDRI AHEYMIDHGA YPSTLGYKGY PKSCCTSLNE VICHGIPDST 130 140 150 160 170 180 VIEDGDIVNI DVTAYIDGVH GDTNATFLAG DVAEERRLLV ERTREATMRA INAVKPGRAL 190 200 210 220 230 240 SVIGRVIESY ANRFGYNVVR DFTGHGIGTT FHNGLVVLHY DQPSVSTIMQ PGMTFTIEPM 250 260 270 280 INLGGLDYEI WDDGWTVVTK DRKWTAQFEH TLLVTDTGVE ILTLP

References

[1]

"The complete genome sequence of Mycobacterium avium subspecies paratuberculosis." Li L., Bannantine J.P., Zhang Q., Amonsin A., May B.J., Alt D., Banerji N., Kanjilal S., Kapur V. Proc. Natl. Acad. Sci. U.S.A. 102:12344-12349(2005) [PubMed: 16116077] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-968 / K-10.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE016958 Genomic DNA. Translation: AAS05251.1.
RefSeq	NP_961868.1. NC_002944.2.
3D structure databases
HSSP	HSSP built from PDB template 1O0X based on UniProtKB Q9X1I7.
ProteinModelPortal	Q73VS7.
SMR	Q73VS7. Positions 4-283.
ModBase	Search...
Protein family/group databases
MEROPS	M24.001.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBMYCT00000038055; EBMYCP00000036444; EBMYCG00000038050.
GeneID	2718800.
GenomeReviews	Gene locus MAP_2934c in contig AE016958_GR.
KEGG	mpa:MAP2934c.
NMPDR	fig|262316.1.peg.2934.
PATRIC	17998598. VBIMycAvi108102_3109.
Organism-specific databases
CMR	Search...
Phylogenomic databases
GeneTree	EBGT00050000016752.
HOGENOM	HBG299384.
OMA	IEPMISE.
ProtClustDB	PRK12896.
Family and domain databases
InterPro	IPR001714. Pept_M24_MAP. IPR000994. Pept_M24_structural-domain. IPR002467. Pept_M24A_MAP1. [Graphical view]
Gene3D	G3DSA:3.90.230.10. Peptidase_M24_cat_core. 1 hit.
KO	K01265.
Pfam	PF00557. Peptidase_M24. 1 hit. [Graphical view]
PRINTS	PR00599. MAPEPTIDASE.
SUPFAM	SSF55920. Peptidase_M24_cat_core. 1 hit.
TIGRFAMs	TIGR00500. Met_pdase_I. 1 hit.
PROSITE	PS00680. MAP_1. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q73VS7_MYCPA

Accession

Primary (citable) accession number: Q73VS7

Entry history

Integrated into UniProtKB/TrEMBL:	July 5, 2004
Last sequence update:	July 5, 2004
Last modified:	December 14, 2011
This is version 57 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)