Q73S94 (RL6_MYCPA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
50S ribosomal protein L6

Gene names

Name:	rplF
Ordered Locus Names:	MAP_4182

Organism

Mycobacterium paratuberculosis [Complete proteome] [HAMAP]

Taxonomic identifier

1770 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium › Mycobacterium avium complex (MAC)

Protein attributes

Sequence length	179 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center By similarity. HAMAP MF_01365_B
Subunit structure	Part of the 50S ribosomal subunit By similarity. HAMAP MF_01365_B
Sequence similarities	Belongs to the ribosomal protein L6P family.

Ontologies

Keywords
Ligand	RNA-binding rRNA-binding
Molecular function	Ribonucleoprotein Ribosomal protein
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	translation Inferred from electronic annotation. Source: InterPro
Cellular component	ribosome Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	rRNA binding Inferred from electronic annotation. Source: UniProtKB-KW structural constituent of ribosome Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 179	179	50S ribosomal protein L6 HAMAP MF_01365_B		PRO_0000260896

Sequences

	Sequence		Length	Mass (Da)
	Q73S94 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: 8E35CA18EC62FE6E	FASTA	179	19,454
	10 20 30 40 50 60 MSRIGKQPVP VPAGVDVTID GQKVSVKGPK GTLDLTVAEP ITVSRNDDGA IVVTRPNDER 70 80 90 100 110 120 RNRSLHGLSR TLVSNLVTGV TQGYTTKMEI FGVGYRVQLK GSNLEFALGY SHPVVIEAPE 130 140 150 160 170 GITFAVQSPT KFSISGIDKQ KVGQISANIR RLRRPDPYKG KGVRYEGEQI RRKVGKTGK

References

[1]

"The complete genome sequence of Mycobacterium avium subspecies paratuberculosis." Li L., Bannantine J.P., Zhang Q., Amonsin A., May B.J., Alt D., Banerji N., Kanjilal S., Kapur V. Proc. Natl. Acad. Sci. U.S.A. 102:12344-12349(2005) [PubMed: 16116077] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-968 / K-10.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE016958 Genomic DNA. Translation: AAS06732.1.
RefSeq	NP_963116.1. NC_002944.2.
3D structure databases
HSSP	HSSP built from PDB template 1C04 based on UniProtKB P02391.
ProteinModelPortal	Q73S94.
SMR	Q73S94. Positions 8-179.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBMYCT00000040260; EBMYCP00000038649; EBMYCG00000040255.
GeneID	2718937.
GenomeReviews	Gene locus MAP_4182 in contig AE016958_GR.
KEGG	mpa:MAP4182.
NMPDR	fig|262316.1.peg.4182.
PATRIC	18001306. VBIMycAvi108102_4454.
Organism-specific databases
CMR	Search...
Phylogenomic databases
GeneTree	EBGT00050000015590.
HOGENOM	HBG606796.
OMA	ALINNMV.
ProtClustDB	PRK05498.
Family and domain databases
HAMAP	MF_01365_B. Ribosomal_L6_B. [Tree]
InterPro	IPR000702. Ribosomal_L6. IPR020040. Ribosomal_L6_a/b-dom. IPR019906. Ribosomal_L6_bac-type. IPR002358. Ribosomal_L6_CS. [Graphical view]
Gene3D	G3DSA:3.90.930.12. Ribosomal_L6. 2 hits.
KO	K02933.
PANTHER	PTHR11655:SF6. PTHR11655:SF6. 1 hit. PTHR11655. Ribosomal_L6. 1 hit.
Pfam	PF00347. Ribosomal_L6. 2 hits. [Graphical view]
PIRSF	PIRSF002162. Ribosomal_L6. 1 hit.
PRINTS	PR00059. RIBOSOMALL6.
SUPFAM	SSF56053. Ribosomal_L6. 2 hits.
TIGRFAMs	TIGR03654. L6_bact. 1 hit.
PROSITE	PS00525. RIBOSOMAL_L6_1. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RL6_MYCPA

Accession

Primary (citable) accession number: Q73S94

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 28, 2006
Last sequence update:	July 5, 2004
Last modified:	January 25, 2012
This is version 47 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program