Q73S13 (GCP_MYCPA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable tRNA threonylcarbamoyladenosine biosynthesis protein Gcp

Alternative name(s):
t(6)A37 threonylcarbamoyladenosine biosynthesis protein

Gene names

Name:	gcp
Ordered Locus Names:	MAP_4263

Organism

Mycobacterium paratuberculosis [Complete proteome] [HAMAP]

Taxonomic identifier

1770 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium › Mycobacterium avium complex (MAC)

Protein attributes

Sequence length	341 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t6A37) in tRNAs that read codons beginning with adenine By similarity. HAMAP MF_01445
Subcellular location	Cytoplasm Potential HAMAP MF_01445.
Sequence similarities	Belongs to the KAE1 / YgjD family.

Ontologies

Keywords
Biological process	tRNA processing
Cellular component	Cytoplasm
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	proteolysis Inferred from electronic annotation. Source: InterPro tRNA processing Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	metalloendopeptidase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 341	341	Probable tRNA threonylcarbamoyladenosine biosynthesis protein Gcp HAMAP MF_01445		PRO_0000303430

Sequences

	Sequence		Length	Mass (Da)
	Q73S13 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: 69F1711F7308373C	FASTA	341	34,723
	10 20 30 40 50 60 MTTILAIETS CDETGVGIAR LDADGAVTLL ADEVASSVDE HVRFGGVVPE IASRAHLEAL 70 80 90 100 110 120 GPTMRRALSA AGVTKPDVVA ATIGPGLAGA LLVGVAAAKA YSAAWGVPFY AVNHLGGHLA 130 140 150 160 170 180 ADVYQHGPLP ECVALLVSGG HTHLLQVRSL GDPIVELGST VDDAAGEAYD KVARLLGLGY 190 200 210 220 230 240 PGGRVLDELA RTGDREAIVF PRGMTGPRDA PYAFSFSGLK TAVARYLESH PDAVNADVAA 250 260 270 280 290 300 GFQEAVADVL TRKAVRAATD LGVTTLLIAG GVAANSRLRE LAEQRCAAAG LTLRIPRPGL 310 320 330 340 CTDNGAMIAS FAAHLVAAGA PPSPLDVPTD PGLPVVKAQV S

References

[1]

"The complete genome sequence of Mycobacterium avium subspecies paratuberculosis." Li L., Bannantine J.P., Zhang Q., Amonsin A., May B.J., Alt D., Banerji N., Kanjilal S., Kapur V. Proc. Natl. Acad. Sci. U.S.A. 102:12344-12349(2005) [PubMed: 16116077] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-968 / K-10.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE016958 Genomic DNA. Translation: AAS06813.1.
RefSeq	NP_963197.1. NC_002944.2.
3D structure databases
ProteinModelPortal	Q73S13.
ModBase	Search...
Protein family/group databases
MEROPS	M22.A01.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBMYCT00000039770; EBMYCP00000038159; EBMYCG00000039765.
GeneID	2720730.
GenomeReviews	Gene locus MAP_4263 in contig AE016958_GR.
KEGG	mpa:MAP4263.
NMPDR	fig|262316.1.peg.4263.
PATRIC	18001472. VBIMycAvi108102_4537.
Organism-specific databases
CMR	Search...
Phylogenomic databases
GeneTree	EBGT00050000017447.
HOGENOM	HBG304663.
OMA	PLYGVNH.
ProtClustDB	PRK09604.
Family and domain databases
HAMAP	MF_01445. gcp. [Tree]
InterPro	IPR022450. Pept_M22_O-sialoglycopept. IPR000905. Peptidase_M22. IPR017860. Peptidase_M22_CS. IPR017861. Peptidase_M22_subgr. [Graphical view]
KO	K01409.
Pfam	PF00814. Peptidase_M22. 1 hit. [Graphical view]
PRINTS	PR00789. OSIALOPTASE.
TIGRFAMs	TIGR03723. Bact_gcp. 1 hit. TIGR00329. Gcp_kae1. 1 hit.
PROSITE	PS01016. GLYCOPROTEASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GCP_MYCPA

Accession

Primary (citable) accession number: Q73S13

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 11, 2007
Last sequence update:	July 5, 2004
Last modified:	January 25, 2012
This is version 50 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program