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Protein
Submitted name:

Adenylate/guanylate cyclase catalytic domain protein

Gene

TDE_0155

Organism
Treponema denticola (strain ATCC 35405 / CIP 103919 / DSM 14222)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Adenylate/guanylate cyclase catalytic domain proteinImported
Gene namesi
Ordered Locus Names:TDE_0155Imported
OrganismiTreponema denticola (strain ATCC 35405 / CIP 103919 / DSM 14222)Imported
Taxonomic identifieri243275 [NCBI]
Taxonomic lineageiBacteriaSpirochaetesSpirochaetalesSpirochaetaceaeTreponema
Proteomesi
  • UP000008212 Componenti: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei193 – 217HelicalSequence analysisAdd BLAST25
Transmembranei224 – 248HelicalSequence analysisAdd BLAST25
Transmembranei260 – 280HelicalSequence analysisAdd BLAST21
Transmembranei287 – 305HelicalSequence analysisAdd BLAST19
Transmembranei317 – 336HelicalSequence analysisAdd BLAST20
Transmembranei343 – 362HelicalSequence analysisAdd BLAST20
Transmembranei368 – 390HelicalSequence analysisAdd BLAST23

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 21Sequence analysisAdd BLAST21
ChainiPRO_500428606022 – 623Sequence analysisAdd BLAST602

Interactioni

Protein-protein interaction databases

STRINGi243275.TDE0155.

Structurei

3D structure databases

ProteinModelPortaliQ73RD4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini444 – 570Guanylate cyclaseInterPro annotationAdd BLAST127

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG41069SM. Bacteria.
COG2114. LUCA.
OMAiTRYENIN.
OrthoDBiPOG091H0AUC.

Family and domain databases

Gene3Di3.30.70.1230. 1 hit.
InterProiIPR011623. 7TMR_DISM_rcpt_extracell_dom1.
IPR001054. A/G_cyclase.
IPR029787. Nucleotide_cyclase.
[Graphical view]
PfamiPF07695. 7TMR-DISM_7TM. 1 hit.
PF00211. Guanylate_cyc. 1 hit.
[Graphical view]
SUPFAMiSSF55073. SSF55073. 1 hit.
PROSITEiPS50125. GUANYLATE_CYCLASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q73RD4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKKFTLIFIC SLFLASCIKP AEPRLDTVVK GVFDAENISV GDIQVLEGEW
60 70 80 90 100
IFIPNKFVSP LEDFTKYTRY ENINTSWHKY GDGLSIYGYG TYALRIKNLS
110 120 130 140 150
TSGVYAIKTA TVSSAFIAYL EGKEIYRSGV VGNSRKFEVF NWDAPFIILP
160 170 180 190 200
TFGKEEVTLV FHVSNFCDNK AGFLKPIEFG FYSDLLNAKN ASVLTLTILA
210 220 230 240 250
GILLLAATFF ISLFIFYPKE KQSLYFGLLA ANFSLRICCY DEFLLTTIIP
260 270 280 290 300
GISGEALFRI GYMTISLGII FAALFINNLF SKIKSRYWFI MLAPGILYII
310 320 330 340 350
INIFAPMRVS SALLQPAQIY VLLFAAYNVI IVMKAASRKD ASAILFLTGF
360 370 380 390 400
SIFLILGVRD VLIANRIIQG FFLSHIGVLV LLIPMAIVVL RNFRDSSDRV
410 420 430 440 450
IGITKQIEAT NEALAKFVPN EFMNFLRKKH VDIKLGDNIL KDMYIAFIHL
460 470 480 490 500
GIYTGLETEK ERLGLLRIYN DTLSNINPII QAHNGFIDKY LTEGLMVLFH
510 520 530 540 550
GSADDVIKCM LKIKSVVQFE NMEREINKLP KIDLAVGIHY GRLMLGTIGE
560 570 580 590 600
EERMDSTVIS DVVNVASRLH FYALKKGVNI FISEVVKKNV TNLPINEVKF
610 620
EYNGLVRFRG KDEPVRIYEV KKL
Length:623
Mass (Da):70,383
Last modified:July 5, 2004 - v1
Checksum:iDD56697E77096C67
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017226 Genomic DNA. Translation: AAS10653.1.
RefSeqiNP_970772.1. NC_002967.9.
WP_002681033.1. NC_002967.9.

Genome annotation databases

EnsemblBacteriaiAAS10653; AAS10653; TDE_0155.
GeneIDi2741743.
KEGGitde:TDE0155.
PATRICi20522568. VBITreDen445_0153.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017226 Genomic DNA. Translation: AAS10653.1.
RefSeqiNP_970772.1. NC_002967.9.
WP_002681033.1. NC_002967.9.

3D structure databases

ProteinModelPortaliQ73RD4.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi243275.TDE0155.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAS10653; AAS10653; TDE_0155.
GeneIDi2741743.
KEGGitde:TDE0155.
PATRICi20522568. VBITreDen445_0153.

Phylogenomic databases

eggNOGiENOG41069SM. Bacteria.
COG2114. LUCA.
OMAiTRYENIN.
OrthoDBiPOG091H0AUC.

Family and domain databases

Gene3Di3.30.70.1230. 1 hit.
InterProiIPR011623. 7TMR_DISM_rcpt_extracell_dom1.
IPR001054. A/G_cyclase.
IPR029787. Nucleotide_cyclase.
[Graphical view]
PfamiPF07695. 7TMR-DISM_7TM. 1 hit.
PF00211. Guanylate_cyc. 1 hit.
[Graphical view]
SUPFAMiSSF55073. SSF55073. 1 hit.
PROSITEiPS50125. GUANYLATE_CYCLASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ73RD4_TREDE
AccessioniPrimary (citable) accession number: Q73RD4
Entry historyi
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: November 2, 2016
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.