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Protein
Submitted name:

Adenylate/guanylate cyclase catalytic domain protein

Gene

TDE_0156

Organism
Treponema denticola (strain ATCC 35405 / CIP 103919 / DSM 14222)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Adenylate/guanylate cyclase catalytic domain proteinImported
Gene namesi
Ordered Locus Names:TDE_0156Imported
OrganismiTreponema denticola (strain ATCC 35405 / CIP 103919 / DSM 14222)Imported
Taxonomic identifieri243275 [NCBI]
Taxonomic lineageiBacteriaSpirochaetesSpirochaetalesSpirochaetaceaeTreponema
Proteomesi
  • UP000008212 Componenti: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei763 – 781HelicalSequence analysisAdd BLAST19

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Interactioni

Protein-protein interaction databases

STRINGi243275.TDE0156.

Structurei

3D structure databases

ProteinModelPortaliQ73RD3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini844 – 970Guanylate cyclaseInterPro annotationAdd BLAST127

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili785 – 819Sequence analysisAdd BLAST35

Sequence similaritiesi

Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG4105BZU. Bacteria.
COG2114. LUCA.
COG3292. LUCA.
OMAiTIWIATS.
OrthoDBiPOG091H0AUC.

Family and domain databases

Gene3Di2.120.10.30. 5 hits.
3.30.70.1230. 1 hit.
InterProiIPR011042. 6-blade_b-propeller_TolB-like.
IPR001054. A/G_cyclase.
IPR018297. A/G_cyclase_CS.
IPR029787. Nucleotide_cyclase.
IPR011110. Reg_prop.
IPR011123. Y_Y_Y.
[Graphical view]
PfamiPF00211. Guanylate_cyc. 1 hit.
PF07494. Reg_prop. 5 hits.
PF07495. Y_Y_Y. 1 hit.
[Graphical view]
SMARTiSM00044. CYCc. 1 hit.
[Graphical view]
SUPFAMiSSF55073. SSF55073. 1 hit.
PROSITEiPS00452. GUANYLATE_CYCLASE_1. 1 hit.
PS50125. GUANYLATE_CYCLASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q73RD3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLKKIFLIAA VILPVMLPLQ SEISFNNLAG SVQTFWSDTN GLPSNRILDI
60 70 80 90 100
MQDETGYIWL ASYDGLIRFD GEVFTEFTEE EHGFTGISPR VLCEDVHGSL
110 120 130 140 150
WVGTNATGLY EYKNKTFTRY GLEDGLPNLS VRAVKFDKNN TLWVGTANGL
160 170 180 190 200
VCKSASGGFM PVLSEDGSGL GLISFILPVQ DMVFVGTNLK GITAIRAGKA
210 220 230 240 250
VPLPSFAAVQ DYTFSTAYVS SDGVIWFGTK DGKIVKVKGD TIAEIIDLEY
260 270 280 290 300
LRGTSINEFL QTLNGTLYAA TNRGVVTLGT GDPEAFSESN GLPNNIVSSL
310 320 330 340 350
CQDRENNLWV GMEHGGIGKF SRGKFLDLTS EKSLPAEAAN AVIQDADKNI
360 370 380 390 400
WIAKDDGIAC IKSSGLSLER SGQIDSVSEI LKGLRVRQVR EDSDGSLFFA
410 420 430 440 450
TYSDKGLLIF SKDGSIRSIT KNDGLPNNRI RFSYSGRDNV MWIGTTACPA
460 470 480 490 500
LYYNGTVTAF TREDGLPNLF ILCALKSSNG KLWLGTDGGG AVEIALSGLA
510 520 530 540 550
EGMPRIHIER ILIKENGLSG NIVFRIVEDS YGNMWFCTSE GLTLYKDGTF
560 570 580 590 600
YSAAQAIGRS GNSVFNILND AENNLWIVTA KELLFVKNDA FVQAVLNKTP
610 620 630 640 650
AENLFRYNRL DGLTGQLAAN AWAYITEDNI LFIPTIKGVS VCDPSGYVPN
660 670 680 690 700
KYEPPVVIEN IFLDGKRFDA AEGVLQVSAR IKRILFKFTA LSYTIPQRVQ
710 720 730 740 750
FEYKLDGYDS EWRSCGTTRE IAYTNLNPGN YVFKVRAANN DGILNRDGSR
760 770 780 790 800
VSFYKRPFFY QTVWFYLSMV LLGSALIFFA VQLRFRALQH RAQELDKKVK
810 820 830 840 850
EKTKELADEK EKSDKLLKNT LPLSIIDELI KMGESKPKLY PAVTVLFADV
860 870 880 890 900
VGFTEWSGHN TPDAVISGLN SLFTHFDGIM DLYGCERIKT LGDGYLACSG
910 920 930 940 950
LTNEKNHAER VVDAAVAMLR SLETFNKEND SCFSIKIGIS SGAITGGIVG
960 970 980 990 1000
VHKYIFDVFG DTVNTAFRLE SVTSPTACTV SESTAALIRG KYGLHKRPDQ
1010 1020 1030 1040 1050
NLKGKGLIPC YYVKYAASDK VSDREEVKAL YGRLVALYKN KEFIECRSVI
1060 1070
AQLDRTLLEP DIGRTIAAVI KHIGM
Length:1,075
Mass (Da):118,411
Last modified:July 5, 2004 - v1
Checksum:i637E7D7D8085B895
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017226 Genomic DNA. Translation: AAS10654.1.
RefSeqiNP_970773.1. NC_002967.9.
WP_010956687.1. NC_002967.9.

Genome annotation databases

EnsemblBacteriaiAAS10654; AAS10654; TDE_0156.
GeneIDi2741744.
KEGGitde:TDE0156.
PATRICi20522570. VBITreDen445_0154.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017226 Genomic DNA. Translation: AAS10654.1.
RefSeqiNP_970773.1. NC_002967.9.
WP_010956687.1. NC_002967.9.

3D structure databases

ProteinModelPortaliQ73RD3.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi243275.TDE0156.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAS10654; AAS10654; TDE_0156.
GeneIDi2741744.
KEGGitde:TDE0156.
PATRICi20522570. VBITreDen445_0154.

Phylogenomic databases

eggNOGiENOG4105BZU. Bacteria.
COG2114. LUCA.
COG3292. LUCA.
OMAiTIWIATS.
OrthoDBiPOG091H0AUC.

Family and domain databases

Gene3Di2.120.10.30. 5 hits.
3.30.70.1230. 1 hit.
InterProiIPR011042. 6-blade_b-propeller_TolB-like.
IPR001054. A/G_cyclase.
IPR018297. A/G_cyclase_CS.
IPR029787. Nucleotide_cyclase.
IPR011110. Reg_prop.
IPR011123. Y_Y_Y.
[Graphical view]
PfamiPF00211. Guanylate_cyc. 1 hit.
PF07494. Reg_prop. 5 hits.
PF07495. Y_Y_Y. 1 hit.
[Graphical view]
SMARTiSM00044. CYCc. 1 hit.
[Graphical view]
SUPFAMiSSF55073. SSF55073. 1 hit.
PROSITEiPS00452. GUANYLATE_CYCLASE_1. 1 hit.
PS50125. GUANYLATE_CYCLASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ73RD3_TREDE
AccessioniPrimary (citable) accession number: Q73RD3
Entry historyi
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: November 2, 2016
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.