Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q73RB6

- PCP_TREDE

UniProt

Q73RB6 - PCP_TREDE

Protein

Pyrrolidone-carboxylate peptidase

Gene

pcp

Organism
Treponema denticola (strain ATCC 35405 / CIP 103919 / DSM 14222)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 68 (01 Oct 2014)
      Sequence version 1 (05 Jul 2004)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Removes 5-oxoproline from various penultimate amino acid residues except L-proline.UniRule annotation

    Catalytic activityi

    Release of an N-terminal pyroglutamyl group from a polypeptide, the second amino acid generally not being Pro.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei78 – 781UniRule annotation
    Active sitei141 – 1411UniRule annotation
    Active sitei168 – 1681UniRule annotation

    GO - Molecular functioni

    1. cysteine-type peptidase activity Source: UniProtKB-KW

    Keywords - Molecular functioni

    Hydrolase, Protease, Thiol protease

    Enzyme and pathway databases

    BioCyciTDEN243275:GJ7G-176-MONOMER.

    Protein family/group databases

    MEROPSiC15.001.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Pyrrolidone-carboxylate peptidaseUniRule annotation (EC:3.4.19.3UniRule annotation)
    Alternative name(s):
    5-oxoprolyl-peptidaseUniRule annotation
    Pyroglutamyl-peptidase IUniRule annotation
    Short name:
    PGP-IUniRule annotation
    Short name:
    PyraseUniRule annotation
    Gene namesi
    Name:pcpUniRule annotation
    Ordered Locus Names:TDE_0175
    OrganismiTreponema denticola (strain ATCC 35405 / CIP 103919 / DSM 14222)
    Taxonomic identifieri243275 [NCBI]
    Taxonomic lineageiBacteriaSpirochaetesSpirochaetalesSpirochaetaceaeTreponema
    ProteomesiUP000008212: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 217217Pyrrolidone-carboxylate peptidasePRO_0000184748Add
    BLAST

    Interactioni

    Subunit structurei

    Homotetramer.UniRule annotation

    Protein-protein interaction databases

    STRINGi243275.TDE0175.

    Structurei

    3D structure databases

    ProteinModelPortaliQ73RB6.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the peptidase C15 family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG2039.
    KOiK01304.
    OMAiHRTIVER.
    OrthoDBiEOG6X1124.

    Family and domain databases

    Gene3Di3.40.630.20. 1 hit.
    HAMAPiMF_00417. Pyrrolid_peptidase.
    InterProiIPR000816. Peptidase_C15.
    IPR016125. Peptidase_C15-like.
    [Graphical view]
    PANTHERiPTHR23402. PTHR23402. 1 hit.
    PfamiPF01470. Peptidase_C15. 1 hit.
    [Graphical view]
    PIRSFiPIRSF015592. Prld-crbxl_pptds. 1 hit.
    PRINTSiPR00706. PYROGLUPTASE.
    PROSITEiPS01334. PYRASE_CYS. 1 hit.
    PS01333. PYRASE_GLU. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q73RB6-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKILVTGFDP FGGEKINPAL ETIKLLPNEI LGAKIIKLEI PTVIGKSVAK    50
    IKDMIEKENP DVVLSIGQAG NRADISVERI GINIDDCRIP DNEGNQPIDE 100
    PVVKDGPAAY FVTLPIKAIV EKVKAGKIPA SISNTAGTFI CNHVCYGVAH 150
    IAAARTAQGK PMKSGFIHIP FLPEQVIGKP ALTPSMSLEM IVKGIELAIE 200
    AIVQNNSDIK VSGGKIC 217
    Length:217
    Mass (Da):23,082
    Last modified:July 5, 2004 - v1
    Checksum:iF1C30CA6E747A7AB
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE017226 Genomic DNA. Translation: AAS10672.1.
    RefSeqiNP_970791.1. NC_002967.9.

    Genome annotation databases

    EnsemblBacteriaiAAS10672; AAS10672; TDE_0175.
    GeneIDi2739348.
    KEGGitde:TDE0175.
    PATRICi20522606. VBITreDen445_0172.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE017226 Genomic DNA. Translation: AAS10672.1 .
    RefSeqi NP_970791.1. NC_002967.9.

    3D structure databases

    ProteinModelPortali Q73RB6.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 243275.TDE0175.

    Protein family/group databases

    MEROPSi C15.001.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAS10672 ; AAS10672 ; TDE_0175 .
    GeneIDi 2739348.
    KEGGi tde:TDE0175.
    PATRICi 20522606. VBITreDen445_0172.

    Phylogenomic databases

    eggNOGi COG2039.
    KOi K01304.
    OMAi HRTIVER.
    OrthoDBi EOG6X1124.

    Enzyme and pathway databases

    BioCyci TDEN243275:GJ7G-176-MONOMER.

    Family and domain databases

    Gene3Di 3.40.630.20. 1 hit.
    HAMAPi MF_00417. Pyrrolid_peptidase.
    InterProi IPR000816. Peptidase_C15.
    IPR016125. Peptidase_C15-like.
    [Graphical view ]
    PANTHERi PTHR23402. PTHR23402. 1 hit.
    Pfami PF01470. Peptidase_C15. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF015592. Prld-crbxl_pptds. 1 hit.
    PRINTSi PR00706. PYROGLUPTASE.
    PROSITEi PS01334. PYRASE_CYS. 1 hit.
    PS01333. PYRASE_GLU. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 35405 / CIP 103919 / DSM 14222.

    Entry informationi

    Entry nameiPCP_TREDE
    AccessioniPrimary (citable) accession number: Q73RB6
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: September 13, 2004
    Last sequence update: July 5, 2004
    Last modified: October 1, 2014
    This is version 68 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Peptidase families
      Classification of peptidase families and list of entries
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3