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Q73QV3 (ALF1_TREDE) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 65. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Fructose-bisphosphate aldolase class 1

EC=4.1.2.13
Alternative name(s):
Fructose-bisphosphate aldolase class I
Short name=FBP aldolase
Gene names
Name:fda
Ordered Locus Names:TDE_0340
OrganismTreponema denticola (strain ATCC 35405 / CIP 103919 / DSM 14222) [Complete proteome] [HAMAP]
Taxonomic identifier243275 [NCBI]
Taxonomic lineageBacteriaSpirochaetesSpirochaetalesSpirochaetaceaeTreponema

Protein attributes

Sequence length295 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-fructose 1,6-bisphosphate = glycerone phosphate + D-glyceraldehyde 3-phosphate. HAMAP-Rule MF_00729

Pathway

Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 4/4. HAMAP-Rule MF_00729

Sequence similarities

Belongs to the class I fructose-bisphosphate aldolase family.

Ontologies

Keywords
   Biological processGlycolysis
   LigandSchiff base
   Molecular functionLyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglycolytic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Molecular_functionfructose-bisphosphate aldolase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 295295Fructose-bisphosphate aldolase class 1 HAMAP-Rule MF_00729
PRO_0000216914

Sites

Active site1761Proton acceptor By similarity
Active site2131Schiff-base intermediate with dihydroxyacetone-P By similarity

Sequences

Sequence LengthMass (Da)Tools
Q73QV3 [UniParc].

Last modified July 5, 2004. Version 1.
Checksum: 5C1A6403A7D4EA20

FASTA29532,805
        10         20         30         40         50         60 
MDKVKLERMK NDKGFIAALD QSGGSTPKAL AAYGVPETAY SNEKEMFDLV HAMRTRIITG 

        70         80         90        100        110        120 
KAFNSNNILG AILFEQTMER EIEGMPTADF LWEKKKILPF LKVDKGLADL KDGVQLMKPI 

       130        140        150        160        170        180 
PNLDAMLKHA VEKHIFGTKM RSVIKEANPK GIKAVVDQQF ELGIQIAKAG LVPIIEPEVD 

       190        200        210        220        230        240 
IKSPDKAKCE EILKKELEEH LKTLPKDLLV MFKLSIPTKE NLYEEFTKHP QVVRVVALSG 

       250        260        270        280        290 
GYSRDDANKL LAKNRGMIAS FSRALAEGLF ASQSDAEFNA TLEKTIKGVY EASIT 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE017226 Genomic DNA. Translation: AAS10835.1.
RefSeqNP_970954.1. NC_002967.9.

3D structure databases

ProteinModelPortalQ73QV3.
SMRQ73QV3. Positions 1-294.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING243275.TDE0340.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAS10835; AAS10835; TDE_0340.
GeneID2739339.
KEGGtde:TDE0340.
PATRIC20522930. VBITreDen445_0329.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG3588.
KOK01623.
OMAPREKAND.
OrthoDBEOG6M6JJT.

Enzyme and pathway databases

BioCycTDEN243275:GJ7G-347-MONOMER.
UniPathwayUPA00109; UER00183.

Family and domain databases

Gene3D3.20.20.70. 1 hit.
HAMAPMF_00729. FBP_aldolase_1.
InterProIPR000741. Aldolase_I.
IPR013785. Aldolase_TIM.
IPR023014. FBP_aldolase_I_bac.
[Graphical view]
PfamPF00274. Glycolytic. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameALF1_TREDE
AccessionPrimary (citable) accession number: Q73QV3
Entry history
Integrated into UniProtKB/Swiss-Prot: March 1, 2005
Last sequence update: July 5, 2004
Last modified: June 11, 2014
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways