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Q73QV3

- ALF1_TREDE

UniProt

Q73QV3 - ALF1_TREDE

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Protein

Fructose-bisphosphate aldolase class 1

Gene

fda

Organism
Treponema denticola (strain ATCC 35405 / CIP 103919 / DSM 14222)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

D-fructose 1,6-bisphosphate = glycerone phosphate + D-glyceraldehyde 3-phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei176 – 1761Proton acceptorUniRule annotation
Active sitei213 – 2131Schiff-base intermediate with dihydroxyacetone-PUniRule annotation

GO - Molecular functioni

  1. fructose-bisphosphate aldolase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Lyase

Keywords - Biological processi

Glycolysis

Keywords - Ligandi

Schiff base

Enzyme and pathway databases

BioCyciTDEN243275:GJ7G-347-MONOMER.
UniPathwayiUPA00109; UER00183.

Names & Taxonomyi

Protein namesi
Recommended name:
Fructose-bisphosphate aldolase class 1UniRule annotation (EC:4.1.2.13UniRule annotation)
Alternative name(s):
Fructose-bisphosphate aldolase class I
Short name:
FBP aldolaseUniRule annotation
Gene namesi
Name:fdaUniRule annotation
Ordered Locus Names:TDE_0340
OrganismiTreponema denticola (strain ATCC 35405 / CIP 103919 / DSM 14222)
Taxonomic identifieri243275 [NCBI]
Taxonomic lineageiBacteriaSpirochaetesSpirochaetalesSpirochaetaceaeTreponema
ProteomesiUP000008212: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 295295Fructose-bisphosphate aldolase class 1PRO_0000216914Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi243275.TDE0340.

Structurei

3D structure databases

ProteinModelPortaliQ73QV3.
SMRiQ73QV3. Positions 1-294.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the class I fructose-bisphosphate aldolase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG3588.
KOiK01623.
OMAiPREKAND.
OrthoDBiEOG6M6JJT.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
HAMAPiMF_00729. FBP_aldolase_1.
InterProiIPR013785. Aldolase_TIM.
IPR000741. FBA_I.
IPR023014. FBA_I_Gram+-type.
[Graphical view]
PfamiPF00274. Glycolytic. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q73QV3-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MDKVKLERMK NDKGFIAALD QSGGSTPKAL AAYGVPETAY SNEKEMFDLV
60 70 80 90 100
HAMRTRIITG KAFNSNNILG AILFEQTMER EIEGMPTADF LWEKKKILPF
110 120 130 140 150
LKVDKGLADL KDGVQLMKPI PNLDAMLKHA VEKHIFGTKM RSVIKEANPK
160 170 180 190 200
GIKAVVDQQF ELGIQIAKAG LVPIIEPEVD IKSPDKAKCE EILKKELEEH
210 220 230 240 250
LKTLPKDLLV MFKLSIPTKE NLYEEFTKHP QVVRVVALSG GYSRDDANKL
260 270 280 290
LAKNRGMIAS FSRALAEGLF ASQSDAEFNA TLEKTIKGVY EASIT
Length:295
Mass (Da):32,805
Last modified:July 5, 2004 - v1
Checksum:i5C1A6403A7D4EA20
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017226 Genomic DNA. Translation: AAS10835.1.
RefSeqiNP_970954.1. NC_002967.9.

Genome annotation databases

EnsemblBacteriaiAAS10835; AAS10835; TDE_0340.
GeneIDi2739339.
KEGGitde:TDE0340.
PATRICi20522930. VBITreDen445_0329.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017226 Genomic DNA. Translation: AAS10835.1 .
RefSeqi NP_970954.1. NC_002967.9.

3D structure databases

ProteinModelPortali Q73QV3.
SMRi Q73QV3. Positions 1-294.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 243275.TDE0340.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAS10835 ; AAS10835 ; TDE_0340 .
GeneIDi 2739339.
KEGGi tde:TDE0340.
PATRICi 20522930. VBITreDen445_0329.

Phylogenomic databases

eggNOGi COG3588.
KOi K01623.
OMAi PREKAND.
OrthoDBi EOG6M6JJT.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00183 .
BioCyci TDEN243275:GJ7G-347-MONOMER.

Family and domain databases

Gene3Di 3.20.20.70. 1 hit.
HAMAPi MF_00729. FBP_aldolase_1.
InterProi IPR013785. Aldolase_TIM.
IPR000741. FBA_I.
IPR023014. FBA_I_Gram+-type.
[Graphical view ]
Pfami PF00274. Glycolytic. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 35405 / CIP 103919 / DSM 14222.

Entry informationi

Entry nameiALF1_TREDE
AccessioniPrimary (citable) accession number: Q73QV3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 1, 2005
Last sequence update: July 5, 2004
Last modified: October 1, 2014
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3