ID   Q73Q13_TREDE            Unreviewed;       708 AA.
AC   Q73Q13;
DT   05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2004, sequence version 1.
DT   27-MAR-2024, entry version 86.
DE   SubName: Full=Sigma factor regulatory protein, putative {ECO:0000313|EMBL:AAS11126.1};
GN   OrderedLocusNames=TDE_0631 {ECO:0000313|EMBL:AAS11126.1};
OS   Treponema denticola (strain ATCC 35405 / DSM 14222 / CIP 103919 / JCM 8153
OS   / KCTC 15104).
OC   Bacteria; Spirochaetota; Spirochaetia; Spirochaetales; Treponemataceae;
OC   Treponema.
OX   NCBI_TaxID=243275 {ECO:0000313|EMBL:AAS11126.1, ECO:0000313|Proteomes:UP000008212};
RN   [1] {ECO:0000313|EMBL:AAS11126.1, ECO:0000313|Proteomes:UP000008212}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 35405 / DSM 14222 / CIP 103919 / JCM 8153 / KCTC 15104
RC   {ECO:0000313|Proteomes:UP000008212};
RX   PubMed=15064399; DOI=10.1073/pnas.0307639101;
RA   Seshadri R., Myers G.S., Tettelin H., Eisen J.A., Heidelberg J.F.,
RA   Dodson R.J., Davidsen T.M., DeBoy R.T., Fouts D.E., Haft D.H., Selengut J.,
RA   Ren Q., Brinkac L.M., Madupu R., Kolonay J., Durkin S.A., Daugherty S.C.,
RA   Shetty J., Shvartsbeyn A., Gebregeorgis E., Geer K., Tsegaye G., Malek J.,
RA   Ayodeji B., Shatsman S., McLeod M.P., Smajs D., Howell J.K., Pal S.,
RA   Amin A., Vashisth P., McNeill T.Z., Xiang Q., Sodergren E., Baca E.,
RA   Weinstock G.M., Norris S.J., Fraser C.M., Paulsen I.T.;
RT   "Comparison of the genome of the oral pathogen Treponema denticola with
RT   other spirochete genomes.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:5646-5651(2004).
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DR   EMBL; AE017226; AAS11126.1; -; Genomic_DNA.
DR   RefSeq; NP_971245.1; NC_002967.9.
DR   RefSeq; WP_002681817.1; NC_002967.9.
DR   AlphaFoldDB; Q73Q13; -.
DR   STRING; 243275.TDE_0631; -.
DR   PaxDb; 243275-TDE_0631; -.
DR   GeneID; 2739356; -.
DR   KEGG; tde:TDE_0631; -.
DR   PATRIC; fig|243275.7.peg.610; -.
DR   eggNOG; COG2208; Bacteria.
DR   HOGENOM; CLU_023575_0_0_12; -.
DR   OrthoDB; 9773346at2; -.
DR   Proteomes; UP000008212; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 3.60.40.10; PPM-type phosphatase domain; 1.
DR   InterPro; IPR036457; PPM-type-like_dom_sf.
DR   InterPro; IPR001932; PPM-type_phosphatase-like_dom.
DR   PANTHER; PTHR43156; STAGE II SPORULATION PROTEIN E-RELATED; 1.
DR   Pfam; PF07228; SpoIIE; 1.
DR   SMART; SM00331; PP2C_SIG; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008212};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        6..23
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        32..55
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        61..82
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        103..122
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        142..164
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        176..195
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        201..221
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        233..258
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        264..285
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        435..454
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          489..707
FT                   /note="PPM-type phosphatase"
FT                   /evidence="ECO:0000259|SMART:SM00331"
SQ   SEQUENCE   708 AA;  81152 MW;  DD6E93A7C5968D19 CRC64;
     MGLIVFEFFF LVVLTILAIS LIFKEEPYAR GLFMVAGMTV ITTLLFLTLI LALYFNFSGV
     VFIISKIFMI GMVSISFFTL QFTVKMPYFE RKKNVSFTVF NGILHLGIAA FVIFFVKGFF
     WNPLSGFKFT SVMIAGNPAS DIFERIVLLV VPVLAMLISI YKVFKEESII YRQQMIIYFL
     ALLFSVIIWS FVYYLSTIFS WAIAITPFGY LLLLFFASFG FSTSMVYDRK QLFLALLRFL
     VFILVFAAVT GYWASWVLTY VRNFYLQVVL LIVGALIFLA IRNFVSQRFK WLLGDTSEYA
     KAIEEKLQQV DYTKGREKVM EDFSNILLDQ LNADSINILI AGENEILEPV YSTLNVTSTF
     DAAQPIFNFL LNENIQVIMR SQVLTNPVFS DVRSELIGFM NRMYAEILIC VREGQKLIGV
     ISISSKKRKE AYTTYDFDVL NSLYSYFFLV VYYLRNIAKQ DIVLILDREI EMSDQIIGSI
     QKNIDIVEKK VIDVDSVAFS AHQLGGDFTD FIRLSEDRYL FLIGDVSGKG LSASMSMVIL
     KSVLHTYLSE TPDFKELVIK INTFIKENLP KGTFLAGLFG IIDFKTTTIY YLNCGIPLMS
     MYIDSYKNVI EIQGEGRVLG FVKNIRPFLK VRKITMNRND IIVFTTDGLL DSKNLKGDKF
     GNDRVSRLIA VNRTKSAKEI SNAIYKTFLD YIAHEIEDDI TIMTFKHI
//