Q73PK2 (ACYP_TREDE) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Acylphosphatase
EC=3.6.1.7

Alternative name(s):
Acylphosphate phosphohydrolase

Gene names

Name:	acyP
Ordered Locus Names:	TDE_0797

Organism

Treponema denticola (strain ATCC 35405 / CIP 103919 / DSM 14222) [Complete proteome] [HAMAP]

Taxonomic identifier

243275 [NCBI]

Taxonomic lineage

Bacteria › Spirochaetes › Spirochaetales › Spirochaetaceae › Treponema

Protein attributes

Sequence length	94 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	An acylphosphate + H2O = a carboxylate + phosphate. HAMAP MF_01450
Sequence similarities	Belongs to the acylphosphatase family. Contains 1 acylphosphatase-like domain.

Ontologies

Keywords
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	acylphosphatase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 94	94	Acylphosphatase HAMAP MF_01450		PRO_0000326838
Regions
	Domain	8 – 94	87	Acylphosphatase-like
Sites
	Active site	23	1	By similarity
	Active site	41	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q73PK2 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: 6287C9D898BB0834	FASTA	94	10,812
	10 20 30 40 50 60 MDKETLRALH VIVKGRVQGV GFRYWTRSLA KSLNVKGRVR NLADYSVEII AEADTDTLGE 70 80 90 FVYALKHEHP YARVESLNSE EVRARGYTDF RIEV

References

[1]

"Comparison of the genome of the oral pathogen Treponema denticola with other spirochete genomes." Seshadri R., Myers G.S.A., Tettelin H., Eisen J.A., Heidelberg J.F., Dodson R.J., Davidsen T.M., DeBoy R.T., Fouts D.E., Haft D.H., Selengut J., Ren Q., Brinkac L.M., Madupu R., Kolonay J.F., Durkin S.A., Daugherty S.C., Shetty J. , Shvartsbeyn A., Gebregeorgis E., Geer K., Tsegaye G., Malek J.A., Ayodeji B., Shatsman S., McLeod M.P., Smajs D., Howell J.K., Pal S., Amin A., Vashisth P., McNeill T.Z., Xiang Q., Sodergren E., Baca E., Weinstock G.M., Norris S.J., Fraser C.M., Paulsen I.T. Proc. Natl. Acad. Sci. U.S.A. 101:5646-5651(2004) [PubMed: 15064399] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 35405 / CIP 103919 / DSM 14222.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE017226 Genomic DNA. Translation: AAS11288.1.
RefSeq	NP_971407.1. NC_002967.9.
3D structure databases
HSSP	HSSP built from PDB template 1W2I based on UniProtKB P84142.
ProteinModelPortal	Q73PK2.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	2740675.
GenomeReviews	Gene locus TDE_0797 in contig AE017226_GR.
KEGG	tde:TDE0797.
NMPDR	fig|243275.1.peg.790.
PATRIC	20523820. VBITreDen445_0770.
TIGR	TDE_0797.
Phylogenomic databases
HOGENOM	HBG750266.
OMA	YFVIISA.
Enzyme and pathway databases
BioCyc	TDEN243275:TDE_0797-MONOMER.
Family and domain databases
HAMAP	MF_01450. Acylphosphatase. [Tree]
InterPro	IPR001792. Acylphosphatase-like. IPR017968. Acylphosphatase_CS. [Graphical view]
KO	K01512.
Pfam	PF00708. Acylphosphatase. 1 hit. [Graphical view]
SUPFAM	SSF54975. Acylphosphatase. 1 hit.
PROSITE	PS00150. ACYLPHOSPHATASE_1. 1 hit. PS00151. ACYLPHOSPHATASE_2. False negative. PS51160. ACYLPHOSPHATASE_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ACYP_TREDE

Accession

Primary (citable) accession number: Q73PK2

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 8, 2008
Last sequence update:	July 5, 2004
Last modified:	January 25, 2012
This is version 52 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program