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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Treponema denticola (strain ATCC 35405 / CIP 103919 / DSM 14222)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:TDE_0971
OrganismiTreponema denticola (strain ATCC 35405 / CIP 103919 / DSM 14222)
Taxonomic identifieri243275 [NCBI]
Taxonomic lineageiBacteriaSpirochaetesSpirochaetalesSpirochaetaceaeTreponema
Proteomesi
  • UP000008212 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002421161 – 590Arginine--tRNA ligaseAdd BLAST590

Proteomic databases

PRIDEiQ73P28.

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi243275.TDE0971.

Structurei

3D structure databases

ProteinModelPortaliQ73P28.
SMRiQ73P28.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi132 – 142"HIGH" regionAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C75. Bacteria.
COG0018. LUCA.
KOiK01887.
OMAiNKPLHLG.
OrthoDBiPOG091H01RF.

Family and domain databases

CDDicd00671. ArgRS_core. 1 hit.
Gene3Di3.30.1360.70. 1 hit.
3.40.50.620. 2 hits.
HAMAPiMF_00123. Arg_tRNA_synth. 1 hit.
InterProiView protein in InterPro
IPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR036695. Arg-tRNA-synth_N_sf.
IPR035684. ArgRS_core.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_Ia_anticodon-bd.
PANTHERiPTHR11956. PTHR11956. 1 hit.
PfamiView protein in Pfam
PF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
PRINTSiPR01038. TRNASYNTHARG.
SMARTiView protein in SMART
SM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
SUPFAMiSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsiTIGR00456. argS. 1 hit.
PROSITEiView protein in PROSITE
PS00178. AA_TRNA_LIGASE_I. 1 hit.

Sequencei

Sequence statusi: Complete.

Q73P28-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEDIKTTWQK IIADTLNGIA PETCDKILPE QINIETPPNP EMGDVAFPLF
60 70 80 90 100
TFAKSFKSSP AKIASDVCAR LLENEDIKKY GMPKAIGPYL NVFLAKGDLA
110 120 130 140 150
SNVLDKVLKE KENYGKTSSL SGKRIMIEFS SPNTNKPLHL GHLRNDALGE
160 170 180 190 200
SISRILKFCG ADVFKVNIIN DRGVHICKSM IAYQKFGEGK TPESENIKSD
210 220 230 240 250
RFVGDMYVAF HKYSQENPEK AEAEAKQMLL DWEAGENKEL IGLWKKMNGW
260 270 280 290 300
AIEGIKETYK RTGISFDKLY FESETYLKGK DQILKGLEAG VFYKEEDGSV
310 320 330 340 350
WVDLAPIKLD KKVLLRSDGT SLYMTQDIGT AISRHKDWPF NQMIYVVGNE
360 370 380 390 400
QEYHFKVLFY VLKQLGFEWA DDLYHLSYGM VNLPEGKMKS REGTVVDADD
410 420 430 440 450
LINSLQDEAL KKIEENGREK EVGDAAVAAE NIAVGALHYF LLQVSPKKDM
460 470 480 490 500
LFNPKESLSF TGNTGPYLQY MGARISSILR KAETAEGKEK LKDGKLNASL
510 520 530 540 550
LTNESEWELL KTLEDFPEQV ERSALRKDPS ALTAYLYELS KAFSRFYRDC
560 570 580 590
PILSGEDADL SYTRMELARA TKIVLQNAMN LVLIPFMEVM
Length:590
Mass (Da):66,634
Last modified:July 5, 2004 - v1
Checksum:i7DBABA318100A0D7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017226 Genomic DNA. Translation: AAS11462.1.
RefSeqiNP_971581.1. NC_002967.9.
WP_002682282.1. NC_002967.9.

Genome annotation databases

EnsemblBacteriaiAAS11462; AAS11462; TDE_0971.
GeneIDi2740543.
KEGGitde:TDE0971.
PATRICifig|243275.7.peg.935.

Similar proteinsi

Entry informationi

Entry nameiSYR_TREDE
AccessioniPrimary (citable) accession number: Q73P28
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: July 5, 2004
Last modified: November 22, 2017
This is version 88 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families