TDE_2115

Functionⁱ

GO - Molecular functionⁱ

catalytic activity Source: InterPro
signal transducer activity Source: InterPro

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: HAMP domain proteinImported
Gene namesⁱ	Ordered Locus Names:TDE_2115Imported
Organismⁱ	Treponema denticola (strain ATCC 35405 / CIP 103919 / DSM 14222)Imported
Taxonomic identifierⁱ	243275 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Bacteria › Spirochaetes › Spirochaetia › Spirochaetales › Spirochaetaceae › Treponema › Treponema denticola
Proteomesⁱ	UP000008212 Componentⁱ: Chromosome

Subcellular locationⁱ

Topology

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Transmembraneⁱ	750 – 773	HelicalSequence analysisAdd BLAST		24
Transmembraneⁱ	816 – 837	HelicalSequence analysisAdd BLAST		22

GO - Cellular componentⁱ

integral component of membrane Source: UniProtKB-KW

Complete GO annotation...

Keywords - Cellular componentⁱ

Membrane

Interactionⁱ

Protein-protein interaction databases

STRINGⁱ	243275.TDE2115.

STRINGⁱ

243275.TDE2115.

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	Q73KV2.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	1097 – 1154	HAMPInterPro annotationAdd BLAST		58

Keywords - Domainⁱ

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGⁱ	ENOG4107SUB. Bacteria. COG2208. LUCA.
OMAⁱ	GKEVQKM.
Database of Orthologous Groups More...OrthoDBⁱ	POG091H0DNP.

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd06225. HAMP. 1 hit.
Gene3Dⁱ	2.60.40.10. 1 hit. 3.60.40.10. 1 hit.
InterProⁱ	View protein in InterPro IPR003660. HAMP_dom. IPR013783. Ig-like_fold. IPR001932. PPM-type_phosphatase_dom. IPR011040. Sialidases.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF07228. SpoIIE. 1 hit.
SMARTⁱ	View protein in SMART SM00304. HAMP. 1 hit. SM00331. PP2C_SIG. 1 hit.
SUPFAMⁱ	SSF50939. SSF50939. 1 hit. SSF81606. SSF81606. 1 hit.
PROSITEⁱ	View protein in PROSITE PS50885. HAMP. 1 hit.

Sequenceⁱ

Sequence statusⁱ: Complete.

Q73KV2-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MKKILTIFLM FLFFISFLSA KEFYWENPSV ISGRNGYFLK SASNANISAS 
        60         70         80         90        100
VWEEVVKSSD TEGLIYISTG VYVNNKWTIN ERIIPPIPYT ADIPSIVSIA 
       110        120        130        140        150
VGNDDSILIA LVKNRNTITI LKSTDYGKTY TVKNIVTEIY DLLSPQLSVA 
       160        170        180        190        200
SNGKYLMFVS HGADEKFSIF YSSSEDGLNW PAFSEFNFAK KMDRIFLPAH 
       210        220        230        240        250
TASSKNDVLV FQALDKSGDR RTYQLFSSFS SDGCSSWSEP VRITDNFDFN 
       260        270        280        290        300
NQRPNLLYIN SEKSIFIVWE QSSYRSEKNS PAYAVLDSKG KLASSIEILP 
       310        320        330        340        350
SGNGTMFSPR IIAYNNKPLI TWSETYDGKS SILIARKEDS IWKTDSVASI 
       360        370        380        390        400
TGSLLFVNPF FVDGNLHIVW QEGVRAAKIM HIEPDHEVAK AQLQPLNFDS 
       410        420        430        440        450
KTLEGRQKIT MKIKFPNDSS GIAGYSYEWS KDVPPEFVAP VIKKLKDETV 
       460        470        480        490        500
LVYEPEEDGL WYLGVRVCDY AGNWSEMTTI SYERDIVPPA APIFDLLALD 
       510        520        530        540        550
KKGFVKSNTF DIKWNPPDLD INGKPETAIN GYIWNLSYLG TVDKFLSYLK 
       560        570        580        590        600
TAGSAFIDDD VVQKVLSDNL DVELNTSKIS SVSNKREFKN YENGLYALTV 
       610        620        630        640        650
SAVDAFGNIG APAVKYFALN KYIPYTYVAD INAVQALDGS ISLSLVGKGF 
       660        670        680        690        700
AAGGEVTSIY VDADGLPPYD LTIEKKDFSV LSDKLISNIK INYLDPGKYY 
       710        720        730        740        750
VGLMHSGRGV YFAQKTISFD DIGNIKLGDY GKVYKYNWLL SAMDSDFSDY 
       760        770        780        790        800
FLIICFTIFI LLIMTLSITG VIYSVKEAIK IKYEVTVLLR GGAMSFGKEK 
       810        820        830        840        850
KLSALKVRGG GLRLKFMMFT MTLIISVILT LDLPLGFRFS ETQERLLAEG 
       860        870        880        890        900
LASNTQVLLE SLSSGAKAYL PSKNVLELGF LPSQVSALKE ASFATITGVH 
       910        920        930        940        950
IDNKKVGYNF VWASNDEDIL SKIDTPDFVV GKSELLLPQL ENVYKKLDEI 
       960        970        980        990       1000
DKEARDSVGE ISDEIQSLTD MTMLIALNTD LKSVERRNEI QSAINQMETK 
      1010       1020       1030       1040       1050
LSSELNGLSI KGSGSYPEFN SKKLSRDITS YLFYKPILYR QTGGQSNFVQ 
      1060       1070       1080       1090       1100
GMVYIQVSTQ SLIEQIDEAT TALRKVILLI SLGALSAGLV GAYILSSIIT 
      1110       1120       1130       1140       1150
APIKKLVRHV AMIAATEDKE LLAGKDVKLR TKDEIGVLGT TINEMTNGLV 
      1160       1170       1180       1190       1200
EAAAASKDLT MGKEIQKMFL PLDLDEAGRK LTSGKTVDDN VEFFGYYEGA 
      1210       1220       1230       1240       1250
RGVSGDYFDY IKLDDRYYAI IKCDVAGKGV PAALIMVEVA TLFLDYFRDW 
      1260       1270       1280       1290       1300
SYKKQGLKID QVVSRINDLL ESRGFKGRFA AFTLCIMDSI SGNVHFCNAG 
      1310       1320       1330       1340       1350
DNVINIYDAA LKKMKEVILT EVSAAGVFPT FMIDMKGGFK VETVKLNSGD 
      1360       1370       1380       1390       1400
VLFLYTDGIE EAKRLFRNSK LEPILCEEPG LEKDAEHETH SVGQDGEELG 
      1410       1420       1430       1440       1450
KPRVCKIIES IFARSSFSLK KWHNPIENEQ FDFDFTNLEG TIEDAVIGLV 
      1460       1470       1480       1490       1500
SVEKIFRMYQ DPKATERDMV QVDKKIDLFL NKHFRQYQTY CGNRVPNTSY 
      1510       1520 
NEYLYYTNVR EDQQYDDLTI LGIKKK

Length:1,526

Mass (Da):170,674

Last modified:July 5, 2004 - v1

Checksum:ⁱE1A7C26D3DFE4EB1

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AE017226 Genomic DNA. Translation: AAS12635.1.
NCBI Reference Sequences More...RefSeqⁱ	NP_972716.1. NC_002967.9. WP_010957154.1. NC_002967.9.

Genome annotation databases

EnsemblBacteriaⁱ	AAS12635; AAS12635; TDE_2115.
GeneIDⁱ	2739374.
KEGGⁱ	tde:TDE2115.
PATRICⁱ	fig\|243275.7.peg.1998.

Similar proteinsⁱ

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:

100%	UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%	UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%	UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AE017226 Genomic DNA. Translation: AAS12635.1.
NCBI Reference Sequences More...RefSeqⁱ	NP_972716.1. NC_002967.9. WP_010957154.1. NC_002967.9.

3D structure databases

ProteinModelPortalⁱ	Q73KV2.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

STRINGⁱ	243275.TDE2115.

STRINGⁱ

243275.TDE2115.

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

EnsemblBacteriaⁱ	AAS12635; AAS12635; TDE_2115.
GeneIDⁱ	2739374.
KEGGⁱ	tde:TDE2115.
PATRICⁱ	fig\|243275.7.peg.1998.

Phylogenomic databases

eggNOGⁱ	ENOG4107SUB. Bacteria. COG2208. LUCA.
OMAⁱ	GKEVQKM.
Database of Orthologous Groups More...OrthoDBⁱ	POG091H0DNP.

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd06225. HAMP. 1 hit.
Gene3Dⁱ	2.60.40.10. 1 hit. 3.60.40.10. 1 hit.
InterProⁱ	View protein in InterPro IPR003660. HAMP_dom. IPR013783. Ig-like_fold. IPR001932. PPM-type_phosphatase_dom. IPR011040. Sialidases.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF07228. SpoIIE. 1 hit.
SMARTⁱ	View protein in SMART SM00304. HAMP. 1 hit. SM00331. PP2C_SIG. 1 hit.
SUPFAMⁱ	SSF50939. SSF50939. 1 hit. SSF81606. SSF81606. 1 hit.
PROSITEⁱ	View protein in PROSITE PS50885. HAMP. 1 hit.
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	Q73KV2_TREDE
Accessionⁱ	Q73KV2Primary (citable) accession number: Q73KV2
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	July 5, 2004
	Last sequence update:	July 5, 2004
	Last modified:	June 7, 2017
	This is version 82 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteomeImported

UniProtKB - Q73KV2 (Q73KV2_TREDE)

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HAMP domain protein

Select a section on the left to see content.

Functionⁱ

GO - Molecular functionⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Topology

GO - Cellular componentⁱ

Keywords - Cellular componentⁱ

Interactionⁱ

Protein-protein interaction databases

Structureⁱ

3D structure databases

Family & Domainsⁱ

Domains and Repeats

Keywords - Domainⁱ

Phylogenomic databases

Family and domain databases

Sequenceⁱ

Sequence databases

Genome annotation databases

Similar proteinsⁱ

Cross-referencesⁱ

Sequence databases

3D structure databases

Protein-protein interaction databases

Protocols and materials databases

Genome annotation databases

Phylogenomic databases

Family and domain databases

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - Q73KV2 (Q73KV2_TREDE)

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HAMP domain protein

TDE_2115

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Cellular componenti

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including length and molecular weight.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Protocols and materials databases

Genome annotation databases

Phylogenomic databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Functionⁱ

GO - Molecular functionⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

GO - Cellular componentⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequenceⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ