HAMP domain protein

<p>Provides any useful information about the protein, mostly biological knowledge.</p><p><a href='../manual/function_section' target='_top'>More...</a></p>Functionⁱ

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:</p><p><a href='../manual/gene_ontology' target='_top'>More...</a></p>GO - Molecular functionⁱ

• catalytic activity Source: InterPro
• signal transducer activity Source: InterPro

Enzyme and pathway databases

<p>Provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.</p><p><a href='../manual/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyⁱ

<p>Provides information on the location and the topology of the mature protein in the cell.</p><p><a href='../manual/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationⁱ

Topology

Feature key	Position(s)	Length	Description	Graphical view	Feature identifier	Actions
<p>Describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.</p><p><a href='../manual/transmem' target='_top'>More...</a></p>Transmembranei	750 – 773	24	HelicalSequence analysis <p>Information which has been generated by the UniProtKB automatic annotation system, without manual validation.</p> <p><a href="/manual/evidences#ECO:0000256">More…</a></p> Automatic assertion according to rulesi SAM:Phobius			Add BLAST
<p>Describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.</p><p><a href='../manual/transmem' target='_top'>More...</a></p>Transmembranei	816 – 837	22	HelicalSequence analysis <p>Information which has been generated by the UniProtKB automatic annotation system, without manual validation.</p> <p><a href="/manual/evidences#ECO:0000256">More…</a></p> Automatic assertion according to rulesi SAM:Phobius			Add BLAST

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:</p><p><a href='../manual/gene_ontology' target='_top'>More...</a></p>GO - Cellular componentⁱ

• integral component of membrane Source: UniProtKB-KW

<p>UniProtKB Keywords constitute a <a target="_top" href="/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componentⁱ

<p>Provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.</p><p><a href='../manual/interaction_section' target='_top'>More...</a></p>Interactionⁱ

Protein-protein interaction databases

<p>Provides information on the tertiary and secondary structure of a protein.</p><p><a href='../manual/structure_section' target='_top'>More...</a></p>Structureⁱ

3D structure databases

<p>Provides information on sequence similarities with other proteins and the domain(s) present in a protein.</p><p><a href='../manual/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	Length	Description	Graphical view	Feature identifier	Actions
<p>Describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.</p><p><a href='../manual/domain' target='_top'>More...</a></p>Domaini	1097 – 1154	58	HAMPInterPro annotation <p>Information which has been generated by the UniProtKB automatic annotation system, without manual validation.</p> <p><a href="/manual/evidences#ECO:0000259">More…</a></p> Automatic assertion inferred from signature matchi PROSITE:PS50885			Add BLAST

<p>UniProtKB Keywords constitute a <a target="_top" href="/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domainⁱ

Phylogenomic databases

Family and domain databases

<p>Displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including length and molecular weight.</p><p><a href='../manual/sequences_section' target='_top'>More...</a></p>Sequenceⁱ

<p>Indicates if the <a href="/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.</p><p><a href='../manual/sequence_status' target='_top'>More...</a></p>Sequence statusⁱ: Complete.

        10         20         30         40         50
MKKILTIFLM FLFFISFLSA KEFYWENPSV ISGRNGYFLK SASNANISAS 
        60         70         80         90        100
VWEEVVKSSD TEGLIYISTG VYVNNKWTIN ERIIPPIPYT ADIPSIVSIA 
       110        120        130        140        150
VGNDDSILIA LVKNRNTITI LKSTDYGKTY TVKNIVTEIY DLLSPQLSVA 
       160        170        180        190        200
SNGKYLMFVS HGADEKFSIF YSSSEDGLNW PAFSEFNFAK KMDRIFLPAH 
       210        220        230        240        250
TASSKNDVLV FQALDKSGDR RTYQLFSSFS SDGCSSWSEP VRITDNFDFN 
       260        270        280        290        300
NQRPNLLYIN SEKSIFIVWE QSSYRSEKNS PAYAVLDSKG KLASSIEILP 
       310        320        330        340        350
SGNGTMFSPR IIAYNNKPLI TWSETYDGKS SILIARKEDS IWKTDSVASI 
       360        370        380        390        400
TGSLLFVNPF FVDGNLHIVW QEGVRAAKIM HIEPDHEVAK AQLQPLNFDS 
       410        420        430        440        450
KTLEGRQKIT MKIKFPNDSS GIAGYSYEWS KDVPPEFVAP VIKKLKDETV 
       460        470        480        490        500
LVYEPEEDGL WYLGVRVCDY AGNWSEMTTI SYERDIVPPA APIFDLLALD 
       510        520        530        540        550
KKGFVKSNTF DIKWNPPDLD INGKPETAIN GYIWNLSYLG TVDKFLSYLK 
       560        570        580        590        600
TAGSAFIDDD VVQKVLSDNL DVELNTSKIS SVSNKREFKN YENGLYALTV 
       610        620        630        640        650
SAVDAFGNIG APAVKYFALN KYIPYTYVAD INAVQALDGS ISLSLVGKGF 
       660        670        680        690        700
AAGGEVTSIY VDADGLPPYD LTIEKKDFSV LSDKLISNIK INYLDPGKYY 
       710        720        730        740        750
VGLMHSGRGV YFAQKTISFD DIGNIKLGDY GKVYKYNWLL SAMDSDFSDY 
       760        770        780        790        800
FLIICFTIFI LLIMTLSITG VIYSVKEAIK IKYEVTVLLR GGAMSFGKEK 
       810        820        830        840        850
KLSALKVRGG GLRLKFMMFT MTLIISVILT LDLPLGFRFS ETQERLLAEG 
       860        870        880        890        900
LASNTQVLLE SLSSGAKAYL PSKNVLELGF LPSQVSALKE ASFATITGVH 
       910        920        930        940        950
IDNKKVGYNF VWASNDEDIL SKIDTPDFVV GKSELLLPQL ENVYKKLDEI 
       960        970        980        990       1000
DKEARDSVGE ISDEIQSLTD MTMLIALNTD LKSVERRNEI QSAINQMETK 
      1010       1020       1030       1040       1050
LSSELNGLSI KGSGSYPEFN SKKLSRDITS YLFYKPILYR QTGGQSNFVQ 
      1060       1070       1080       1090       1100
GMVYIQVSTQ SLIEQIDEAT TALRKVILLI SLGALSAGLV GAYILSSIIT 
      1110       1120       1130       1140       1150
APIKKLVRHV AMIAATEDKE LLAGKDVKLR TKDEIGVLGT TINEMTNGLV 
      1160       1170       1180       1190       1200
EAAAASKDLT MGKEIQKMFL PLDLDEAGRK LTSGKTVDDN VEFFGYYEGA 
      1210       1220       1230       1240       1250
RGVSGDYFDY IKLDDRYYAI IKCDVAGKGV PAALIMVEVA TLFLDYFRDW 
      1260       1270       1280       1290       1300
SYKKQGLKID QVVSRINDLL ESRGFKGRFA AFTLCIMDSI SGNVHFCNAG 
      1310       1320       1330       1340       1350
DNVINIYDAA LKKMKEVILT EVSAAGVFPT FMIDMKGGFK VETVKLNSGD 
      1360       1370       1380       1390       1400
VLFLYTDGIE EAKRLFRNSK LEPILCEEPG LEKDAEHETH SVGQDGEELG 
      1410       1420       1430       1440       1450
KPRVCKIIES IFARSSFSLK KWHNPIENEQ FDFDFTNLEG TIEDAVIGLV 
      1460       1470       1480       1490       1500
SVEKIFRMYQ DPKATERDMV QVDKKIDLFL NKHFRQYQTY CGNRVPNTSY 
      1510       1520 
NEYLYYTNVR EDQQYDDLTI LGIKKK                       

Sequence databases

Genome annotation databases

<p>Is used to point to information related to entries and found in data collections other than UniProtKB.</p><p><a href='../manual/cross_references_section' target='_top'>More...</a></p>Cross-referencesⁱ

Sequence databases

3D structure databases

Protein-protein interaction databases

Protocols and materials databases

Genome annotation databases

Phylogenomic databases

Enzyme and pathway databases

Family and domain databases

<p>Provides general information on the entry.</p><p><a href='../manual/entry_information_section' target='_top'>More...</a></p>Entry informationⁱ

<p>Contains any relevant information that doesn’t fit in any other defined sections</p><p><a href='../manual/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousⁱ

<p>UniProtKB Keywords constitute a <a target="_top" href="/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termⁱ

<p>Provides links to the UniProt Reference Clusters (<a href="/help/uniref">UniRef</a>). UniRef consists of clusters for UniProtKB sequences (including isoforms) and selected UniParc sequences, in order to obtain complete coverage of the sequence space at resolutions of 100%, 90% and 50% identity.</p><p><a href='../manual/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsⁱ