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Q73K18

- G6PI_TREDE

UniProt

Q73K18 - G6PI_TREDE

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Protein
Glucose-6-phosphate isomerase
Gene
pgi, TDE_2573
Organism
Treponema denticola (strain ATCC 35405 / CIP 103919 / DSM 14222)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei356 – 3561Proton donor By similarity
Active sitei387 – 3871 By similarity
Active sitei502 – 5021 By similarity

GO - Molecular functioni

  1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. gluconeogenesis Source: UniProtKB-HAMAP
  2. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Gluconeogenesis, Glycolysis

Enzyme and pathway databases

BioCyciTDEN243275:GJ7G-2618-MONOMER.
UniPathwayiUPA00109; UER00181.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomerase (EC:5.3.1.9)
Short name:
GPI
Alternative name(s):
Phosphoglucose isomerase
Short name:
PGI
Phosphohexose isomerase
Short name:
PHI
Gene namesi
Name:pgi
Ordered Locus Names:TDE_2573
OrganismiTreponema denticola (strain ATCC 35405 / CIP 103919 / DSM 14222)
Taxonomic identifieri243275 [NCBI]
Taxonomic lineageiBacteriaSpirochaetesSpirochaetalesSpirochaetaceaeTreponema
ProteomesiUP000008212: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 525525Glucose-6-phosphate isomeraseUniRule annotation
PRO_0000180760Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi243275.TDE2573.

Structurei

3D structure databases

ProteinModelPortaliQ73K18.

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.

Phylogenomic databases

eggNOGiCOG0166.
KOiK01810.
OMAiISIYESN.
OrthoDBiEOG64R61J.

Family and domain databases

Gene3Di1.10.1390.10. 1 hit.
HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q73K18-1 [UniParc]FASTAAdd to Basket

« Hide

MEWKNLDKCT SFTQLQKAHK EQAENLKLAD IFDTENSVKR VKNYSVKMGG    50
NLKYNYAAKP VNDEILKALQ SLADEQKLIE KYELLLNGDF INTGENRMVL 100
HQLTRGQLKN DVVYKGVNMR SFYLNELKKI KEFSEAVHSG KIKTSQGKVF 150
TDVVQIGIGG SDLGPRAMYI ALKNRAKKKM RAHFISNVDP DDAAEVLNSI 200
NLASTLFILV SKSGTTQETL ANERFVKSVL EKNGLDCKKQ MLAVTSETSP 250
LANNPDYLTS FYMDDFIGGR YSSTSVCGAA VLALAFGMET VEAFLKGAAE 300
GDKLSLNKNI KENASLLDAL LGVYERNILG CSATAILPYS QALSRFPAHL 350
QQLDMESNGK TVNRFGEKVS YKTGPVIFGE PGTNGQHSFY QLLHQGSDII 400
PLQFIGFKKS QIGLDIESEG STNMQKLNAN LAAQIMAFAA GKTDENKNKD 450
FAGNRPASLI YGEELNPENL GALLAHYENK VMFQGFIWNL NSFDQEGVQL 500
GKTLAKKVLS NDMPPALKAF SEFLL 525
Length:525
Mass (Da):58,030
Last modified:July 5, 2004 - v1
Checksum:i57A70CF75C24C579
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE017226 Genomic DNA. Translation: AAS13090.1.
RefSeqiNP_973171.1. NC_002967.9.

Genome annotation databases

EnsemblBacteriaiAAS13090; AAS13090; TDE_2573.
GeneIDi2739938.
KEGGitde:TDE2573.
PATRICi20527206. VBITreDen445_2432.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE017226 Genomic DNA. Translation: AAS13090.1 .
RefSeqi NP_973171.1. NC_002967.9.

3D structure databases

ProteinModelPortali Q73K18.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 243275.TDE2573.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAS13090 ; AAS13090 ; TDE_2573 .
GeneIDi 2739938.
KEGGi tde:TDE2573.
PATRICi 20527206. VBITreDen445_2432.

Phylogenomic databases

eggNOGi COG0166.
KOi K01810.
OMAi ISIYESN.
OrthoDBi EOG64R61J.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00181 .
BioCyci TDEN243275:GJ7G-2618-MONOMER.

Family and domain databases

Gene3Di 1.10.1390.10. 1 hit.
HAMAPi MF_00473. G6P_isomerase.
InterProi IPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view ]
PANTHERi PTHR11469. PTHR11469. 1 hit.
Pfami PF00342. PGI. 1 hit.
[Graphical view ]
PRINTSi PR00662. G6PISOMERASE.
PROSITEi PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 35405 / CIP 103919 / DSM 14222.

Entry informationi

Entry nameiG6PI_TREDE
AccessioniPrimary (citable) accession number: Q73K18
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 29, 2005
Last sequence update: July 5, 2004
Last modified: June 11, 2014
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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