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Q73K18

- G6PI_TREDE

UniProt

Q73K18 - G6PI_TREDE

Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Treponema denticola (strain ATCC 35405 / CIP 103919 / DSM 14222)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 67 (01 Oct 2014)
      Sequence version 1 (05 Jul 2004)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei356 – 3561Proton donorUniRule annotation
    Active sitei387 – 3871UniRule annotation
    Active sitei502 – 5021UniRule annotation

    GO - Molecular functioni

    1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. gluconeogenesis Source: UniProtKB-HAMAP
    2. glycolytic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Isomerase

    Keywords - Biological processi

    Gluconeogenesis, Glycolysis

    Enzyme and pathway databases

    BioCyciTDEN243275:GJ7G-2618-MONOMER.
    UniPathwayiUPA00109; UER00181.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
    Short name:
    GPIUniRule annotation
    Alternative name(s):
    Phosphoglucose isomeraseUniRule annotation
    Short name:
    PGIUniRule annotation
    Phosphohexose isomeraseUniRule annotation
    Short name:
    PHIUniRule annotation
    Gene namesi
    Name:pgiUniRule annotation
    Ordered Locus Names:TDE_2573
    OrganismiTreponema denticola (strain ATCC 35405 / CIP 103919 / DSM 14222)
    Taxonomic identifieri243275 [NCBI]
    Taxonomic lineageiBacteriaSpirochaetesSpirochaetalesSpirochaetaceaeTreponema
    ProteomesiUP000008212: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 525525Glucose-6-phosphate isomerasePRO_0000180760Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi243275.TDE2573.

    Structurei

    3D structure databases

    ProteinModelPortaliQ73K18.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the GPI family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0166.
    KOiK01810.
    OMAiISIYESN.
    OrthoDBiEOG64R61J.

    Family and domain databases

    Gene3Di1.10.1390.10. 1 hit.
    HAMAPiMF_00473. G6P_isomerase.
    InterProiIPR001672. G6P_Isomerase.
    IPR023096. G6P_Isomerase_C.
    IPR018189. Phosphoglucose_isomerase_CS.
    [Graphical view]
    PANTHERiPTHR11469. PTHR11469. 1 hit.
    PfamiPF00342. PGI. 1 hit.
    [Graphical view]
    PRINTSiPR00662. G6PISOMERASE.
    PROSITEiPS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
    PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q73K18-1 [UniParc]FASTAAdd to Basket

    « Hide

    MEWKNLDKCT SFTQLQKAHK EQAENLKLAD IFDTENSVKR VKNYSVKMGG    50
    NLKYNYAAKP VNDEILKALQ SLADEQKLIE KYELLLNGDF INTGENRMVL 100
    HQLTRGQLKN DVVYKGVNMR SFYLNELKKI KEFSEAVHSG KIKTSQGKVF 150
    TDVVQIGIGG SDLGPRAMYI ALKNRAKKKM RAHFISNVDP DDAAEVLNSI 200
    NLASTLFILV SKSGTTQETL ANERFVKSVL EKNGLDCKKQ MLAVTSETSP 250
    LANNPDYLTS FYMDDFIGGR YSSTSVCGAA VLALAFGMET VEAFLKGAAE 300
    GDKLSLNKNI KENASLLDAL LGVYERNILG CSATAILPYS QALSRFPAHL 350
    QQLDMESNGK TVNRFGEKVS YKTGPVIFGE PGTNGQHSFY QLLHQGSDII 400
    PLQFIGFKKS QIGLDIESEG STNMQKLNAN LAAQIMAFAA GKTDENKNKD 450
    FAGNRPASLI YGEELNPENL GALLAHYENK VMFQGFIWNL NSFDQEGVQL 500
    GKTLAKKVLS NDMPPALKAF SEFLL 525
    Length:525
    Mass (Da):58,030
    Last modified:July 5, 2004 - v1
    Checksum:i57A70CF75C24C579
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE017226 Genomic DNA. Translation: AAS13090.1.
    RefSeqiNP_973171.1. NC_002967.9.

    Genome annotation databases

    EnsemblBacteriaiAAS13090; AAS13090; TDE_2573.
    GeneIDi2739938.
    KEGGitde:TDE2573.
    PATRICi20527206. VBITreDen445_2432.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE017226 Genomic DNA. Translation: AAS13090.1 .
    RefSeqi NP_973171.1. NC_002967.9.

    3D structure databases

    ProteinModelPortali Q73K18.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 243275.TDE2573.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAS13090 ; AAS13090 ; TDE_2573 .
    GeneIDi 2739938.
    KEGGi tde:TDE2573.
    PATRICi 20527206. VBITreDen445_2432.

    Phylogenomic databases

    eggNOGi COG0166.
    KOi K01810.
    OMAi ISIYESN.
    OrthoDBi EOG64R61J.

    Enzyme and pathway databases

    UniPathwayi UPA00109 ; UER00181 .
    BioCyci TDEN243275:GJ7G-2618-MONOMER.

    Family and domain databases

    Gene3Di 1.10.1390.10. 1 hit.
    HAMAPi MF_00473. G6P_isomerase.
    InterProi IPR001672. G6P_Isomerase.
    IPR023096. G6P_Isomerase_C.
    IPR018189. Phosphoglucose_isomerase_CS.
    [Graphical view ]
    PANTHERi PTHR11469. PTHR11469. 1 hit.
    Pfami PF00342. PGI. 1 hit.
    [Graphical view ]
    PRINTSi PR00662. G6PISOMERASE.
    PROSITEi PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
    PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 35405 / CIP 103919 / DSM 14222.

    Entry informationi

    Entry nameiG6PI_TREDE
    AccessioniPrimary (citable) accession number: Q73K18
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: March 29, 2005
    Last sequence update: July 5, 2004
    Last modified: October 1, 2014
    This is version 67 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3