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Q73K18

- G6PI_TREDE

UniProt

Q73K18 - G6PI_TREDE

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Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Treponema denticola (strain ATCC 35405 / CIP 103919 / DSM 14222)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei356 – 3561Proton donorUniRule annotation
Active sitei387 – 3871UniRule annotation
Active sitei502 – 5021UniRule annotation

GO - Molecular functioni

  1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. gluconeogenesis Source: UniProtKB-HAMAP
  2. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Gluconeogenesis, Glycolysis

Enzyme and pathway databases

BioCyciTDEN243275:GJ7G-2618-MONOMER.
UniPathwayiUPA00109; UER00181.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
Short name:
GPIUniRule annotation
Alternative name(s):
Phosphoglucose isomeraseUniRule annotation
Short name:
PGIUniRule annotation
Phosphohexose isomeraseUniRule annotation
Short name:
PHIUniRule annotation
Gene namesi
Name:pgiUniRule annotation
Ordered Locus Names:TDE_2573
OrganismiTreponema denticola (strain ATCC 35405 / CIP 103919 / DSM 14222)
Taxonomic identifieri243275 [NCBI]
Taxonomic lineageiBacteriaSpirochaetesSpirochaetalesSpirochaetaceaeTreponema
ProteomesiUP000008212: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 525525Glucose-6-phosphate isomerasePRO_0000180760Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi243275.TDE2573.

Structurei

3D structure databases

ProteinModelPortaliQ73K18.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0166.
KOiK01810.
OMAiISIYESN.
OrthoDBiEOG64R61J.

Family and domain databases

Gene3Di1.10.1390.10. 1 hit.
HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q73K18-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MEWKNLDKCT SFTQLQKAHK EQAENLKLAD IFDTENSVKR VKNYSVKMGG
60 70 80 90 100
NLKYNYAAKP VNDEILKALQ SLADEQKLIE KYELLLNGDF INTGENRMVL
110 120 130 140 150
HQLTRGQLKN DVVYKGVNMR SFYLNELKKI KEFSEAVHSG KIKTSQGKVF
160 170 180 190 200
TDVVQIGIGG SDLGPRAMYI ALKNRAKKKM RAHFISNVDP DDAAEVLNSI
210 220 230 240 250
NLASTLFILV SKSGTTQETL ANERFVKSVL EKNGLDCKKQ MLAVTSETSP
260 270 280 290 300
LANNPDYLTS FYMDDFIGGR YSSTSVCGAA VLALAFGMET VEAFLKGAAE
310 320 330 340 350
GDKLSLNKNI KENASLLDAL LGVYERNILG CSATAILPYS QALSRFPAHL
360 370 380 390 400
QQLDMESNGK TVNRFGEKVS YKTGPVIFGE PGTNGQHSFY QLLHQGSDII
410 420 430 440 450
PLQFIGFKKS QIGLDIESEG STNMQKLNAN LAAQIMAFAA GKTDENKNKD
460 470 480 490 500
FAGNRPASLI YGEELNPENL GALLAHYENK VMFQGFIWNL NSFDQEGVQL
510 520
GKTLAKKVLS NDMPPALKAF SEFLL
Length:525
Mass (Da):58,030
Last modified:July 5, 2004 - v1
Checksum:i57A70CF75C24C579
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017226 Genomic DNA. Translation: AAS13090.1.
RefSeqiNP_973171.1. NC_002967.9.

Genome annotation databases

EnsemblBacteriaiAAS13090; AAS13090; TDE_2573.
GeneIDi2739938.
KEGGitde:TDE2573.
PATRICi20527206. VBITreDen445_2432.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017226 Genomic DNA. Translation: AAS13090.1 .
RefSeqi NP_973171.1. NC_002967.9.

3D structure databases

ProteinModelPortali Q73K18.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 243275.TDE2573.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAS13090 ; AAS13090 ; TDE_2573 .
GeneIDi 2739938.
KEGGi tde:TDE2573.
PATRICi 20527206. VBITreDen445_2432.

Phylogenomic databases

eggNOGi COG0166.
KOi K01810.
OMAi ISIYESN.
OrthoDBi EOG64R61J.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00181 .
BioCyci TDEN243275:GJ7G-2618-MONOMER.

Family and domain databases

Gene3Di 1.10.1390.10. 1 hit.
HAMAPi MF_00473. G6P_isomerase.
InterProi IPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view ]
PANTHERi PTHR11469. PTHR11469. 1 hit.
Pfami PF00342. PGI. 1 hit.
[Graphical view ]
PRINTSi PR00662. G6PISOMERASE.
PROSITEi PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 35405 / CIP 103919 / DSM 14222.

Entry informationi

Entry nameiG6PI_TREDE
AccessioniPrimary (citable) accession number: Q73K18
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 29, 2005
Last sequence update: July 5, 2004
Last modified: October 29, 2014
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3