Q73I07 (DCD_WOLPM) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Deoxycytidine triphosphate deaminase
Short name=dCTP deaminase
EC=3.5.4.13

Gene names

Name:	dcd
Ordered Locus Names:	WD_0379

Organism

Wolbachia pipientis wMel [Complete proteome] [HAMAP]

Taxonomic identifier

163164 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Anaplasmataceae › Wolbachieae › Wolbachia

Protein attributes

Sequence length	185 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	dCTP + H2O = dUTP + NH3. HAMAP MF_00146
Pathway	Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP (dUTP route): step 1/2. HAMAP MF_00146
Sequence similarities	Belongs to the dCTP deaminase family.

Ontologies

Keywords
Biological process	Nucleotide metabolism
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	dUTP biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	dCTP deaminase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 185	185	Deoxycytidine triphosphate deaminase HAMAP MF_00146		PRO_1000009827

Sequences

	Sequence		Length	Mass (Da)
	Q73I07 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: 2CC29744BCD570B4	FASTA	185	20,693
	10 20 30 40 50 60 MAVMPDKWIR EKAENFGMIE PFVNHKSSKG VISFGLSSYG YDARVDNKFK IFTNVNSAIV 70 80 90 100 110 120 DPKNFSENSF IDKETDVCII PPNSFVLAST VEYFRIPRNV LVICVGKSTY ARCGIIVNVT 130 140 150 160 170 180 PLEPGWEGHV TLEFSNTTPL PAKIYANEGA CQFVFLSGES ECEKSYDDMK GKYMNQHGIT LPLVK

References

[1]

"Phylogenomics of the reproductive parasite Wolbachia pipientis wMel: a streamlined genome overrun by mobile genetic elements." Wu M., Sun L.V., Vamathevan J.J., Riegler M., DeBoy R.T., Brownlie J.C., McGraw E.A., Martin W., Esser C., Ahmadinejad N., Wiegand C., Madupu R., Beanan M.J., Brinkac L.M., Daugherty S.C., Durkin A.S., Kolonay J.F., Nelson W.C. , Mohamoud Y., Lee P., Berry K.J., Young M.B., Utterback T.R., Weidman J.F., Nierman W.C., Paulsen I.T., Nelson K.E., Tettelin H., O'Neill S.L., Eisen J.A. PLoS Biol. 2:327-341(2004) [PubMed: 15024419] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE017196 Genomic DNA. Translation: AAS14105.1.
RefSeq	NP_966171.1. NC_002978.6.
3D structure databases
ProteinModelPortal	Q73I07.
ModBase	Search...
Protein-protein interaction databases
STRING	Q73I07.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBWOLT00000004678; EBWOLP00000004235; EBWOLG00000004678.
GeneID	2737899.
GenomeReviews	Gene locus WD_0379 in contig AE017196_GR.
KEGG	wol:WD0379.
PATRIC	24029340. VBIWolEnd21207_0379.
TIGR	WD_0379.
Phylogenomic databases
GeneTree	EBGT00050000031024.
HOGENOM	HBG553199.
OMA	MEYFRIP.
PhylomeDB	Q73I07.
ProtClustDB	PRK00416.
Enzyme and pathway databases
BioCyc	WPIP955:WD_0379-MONOMER.
Family and domain databases
HAMAP	MF_00146. dCTP_deaminase. [Tree]
InterPro	IPR011962. dCTP_deam. IPR008180. dUTP_pyroPase. [Graphical view]
KO	K01494.
Pfam	PF00692. dUTPase. 1 hit. [Graphical view]
TIGRFAMs	TIGR02274. DCTP_deam. 1 hit.
ProtoNet	Search...

Entry information

Entry name

DCD_WOLPM

Accession

Primary (citable) accession number: Q73I07

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	July 5, 2004
Last modified:	January 25, 2012
This is version 47 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program