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Q73FV9 (Q73FV9_WOLPM) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 59. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesSubmitted name:
Coproporphyrinogen III oxidase, aerobic, degenerate EMBL AAS14860.1
Gene names
Ordered Locus Names:WD_1214
OrganismWolbachia pipientis wMel [Complete proteome] [HAMAP]
Taxonomic identifier163164 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Anaplasmataceae › Wolbachieae › Wolbachia

Protein attributes

Sequence length256 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III By similarity. SAAS SAAS018375

Catalytic activity

Coproporphyrinogen-III + O2 + 2 H+ = protoporphyrinogen-IX + 2 CO2 + 2 H2O. SAAS SAAS018375

Pathway

Porphyrin metabolism; protoporphyrin-IX biosynthesis; protoporphyrinogen-IX from coproporphyrinogen-III (O2 route): step 1/1. SAAS SAAS018375

Subunit structure

Homodimer By similarity. SAAS SAAS018375

Ontologies

Keywords
   Biological processPorphyrin biosynthesis SAAS SAAS018375
   Molecular functionOxidoreductase SAAS SAAS018375
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processporphyrin-containing compound biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functioncoproporphyrinogen oxidase activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
Q73FV9 [UniParc].

Last modified July 5, 2004. Version 1.
Checksum: CDFED99C70E11296

FASTA25629,481
        10         20         30         40         50         60 
MIESFLLIEK QSSAEPKIEK RKWDRPGGGG GESTIIFGNV FEKVGVNVSK VHGKFADSAI 

        70         80         90        100        110        120 
NEIPGASESN GEFWASGISL VSHMQSPLIP AAHMNTRLIY TSKQWFGGGM DFTPIYKNEE 

       130        140        150        160        170        180 
DCKYIHESIK MTCDRFDTGY YPKFKEQCDN YFFLQHRKEP RGIGGIFYDN LSSSNWENDF 

       190        200        210        220        230        240 
EFTKAVGEAF LEIYLHIIRK HIQKSWTKEQ RENQLIKRGR YVEFNLLYDR GTRFGLMTDG 

       250 
NPDAIMMSMP PLVKWL

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References

[1]"Phylogenomics of the reproductive parasite Wolbachia pipientis wMel: a streamlined genome overrun by mobile genetic elements."
Wu M., Sun L.V., Vamathevan J.J., Riegler M., DeBoy R.T., Brownlie J.C., McGraw E.A., Martin W., Esser C., Ahmadinejad N., Wiegand C., Madupu R., Beanan M.J., Brinkac L.M., Daugherty S.C., Durkin A.S., Kolonay J.F., Nelson W.C. expand/collapse author list , Mohamoud Y., Lee P., Berry K.J., Young M.B., Utterback T.R., Weidman J.F., Nierman W.C., Paulsen I.T., Nelson K.E., Tettelin H., O'Neill S.L., Eisen J.A.
PLoS Biol. 2:327-341(2004) [PubMed: 15024419] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE017196 Genomic DNA. Translation: AAS14860.1.
RefSeqNP_966926.1. NC_002978.6.

3D structure databases

ProteinModelPortalQ73FV9.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ73FV9.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBWOLT00000004160; EBWOLP00000003717; EBWOLG00000004160.
GeneID2738539.
GenomeReviewsGene locus WD_1214 in contig AE017196_GR.
KEGGwol:WD1214.
PATRIC24031021. VBIWolEnd21207_1197.
TIGRWD_1214.

Phylogenomic databases

GeneTreeEBGT00050000031207.
HOGENOMHBG631180.
OMAGKEPVWW.
PhylomeDBQ73FV9.
ProtClustDBPRK05330.

Family and domain databases

InterProIPR001260. Coprogen_oxidase_aer.
IPR018375. Coprogen_oxidase_CS.
[Graphical view]
Gene3DG3DSA:3.40.1500.10. Coprogen_oxidas. 1 hit.
KOK00228.
PANTHERPTHR10755. Coprogen_oxidas. 1 hit.
PfamPF01218. Coprogen_oxidas. 1 hit.
[Graphical view]
PIRSFPIRSF000166. Coproporphyri_ox. 1 hit.
PRINTSPR00073. COPRGNOXDASE.
SUPFAMSSF102886. Coprogen_oxidas. 1 hit.
PROSITEPS01021. COPROGEN_OXIDASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ73FV9_WOLPM
AccessionPrimary (citable) accession number: Q73FV9
Entry history
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: December 14, 2011
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info