Q73F50 (GLMM_BACC1) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Phosphoglucosamine mutase
EC=5.4.2.10

Gene names

Name:	glmM
Ordered Locus Names:	BCE_0157

Organism

Bacillus cereus (strain ATCC 10987) [Complete proteome] [HAMAP]

Taxonomic identifier

222523 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus › Bacillus cereus group

Protein attributes

Sequence length	448 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate By similarity. HAMAP MF_01554_B
Catalytic activity	Alpha-D-glucosamine 1-phosphate = D-glucosamine 6-phosphate. HAMAP MF_01554_B
Cofactor	Binds 1 magnesium ion per subunit By similarity. HAMAP MF_01554_B
Post-translational modification	Activated by phosphorylation By similarity. HAMAP MF_01554_B
Sequence similarities	Belongs to the phosphohexose mutase family.

Ontologies

Keywords
Ligand	Magnesium Metal-binding
Molecular function	Isomerase
PTM	Phosphoprotein
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	magnesium ion binding Inferred from electronic annotation. Source: InterPro phosphoglucosamine mutase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 448	448	Phosphoglucosamine mutase HAMAP MF_01554_B		PRO_0000147840
Sites
	Active site	100	1	Phosphoserine intermediate By similarity
	Metal binding	100	1	Magnesium; via phosphate group By similarity
	Metal binding	240	1	Magnesium By similarity
	Metal binding	242	1	Magnesium By similarity
	Metal binding	244	1	Magnesium By similarity
Amino acid modifications
	Modified residue	100	1	Phosphoserine By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q73F50 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: F871074D653A57A6	FASTA	448	48,417
	10 20 30 40 50 60 MGKYFGTDGV RGVANQELTP ELAFKIGRFG GYVLTKDTDR PKVIIGRDTR ISGHMLEGAL 70 80 90 100 110 120 VAGLLSTGAE VMRLGVISTP GVAYLTKALD AQAGVMISAS HNPVQDNGIK FFGSDGFKLT 130 140 150 160 170 180 DEQEAEIEAL LDKEVDELPR PTGTNLGQVS DYFEGGQKYL QYIKQTVEED FSGLHIALDC 190 200 210 220 230 240 AHGATSSLAP YLFADLEADI STMGTSPNGM NINDGVGSTH PEVLAELVKE KGADIGLAFD 250 260 270 280 290 300 GDGDRLIAVD EKGNIVDGDQ IMFICAKYMK ETGQLKHNTV VSTVMSNLGF YKALEANGIT 310 320 330 340 350 360 SDKTAVGDRY VMEEMKRGGY NLGGEQSGHI ILLDYITTGD GMLSALQLVN IMKMTKKPLS 370 380 390 400 410 420 ELAGEMTKFP QLLVNVRVTD KKLALENEKI KEIIRVVEEE MNGDGRILVR PSGTEPLIRV 430 440 MAEAPTQEVC DAYVHRIVEV VKAEVGAE

References

[1]

"The genome sequence of Bacillus cereus ATCC 10987 reveals metabolic adaptations and a large plasmid related to Bacillus anthracis pXO1." Rasko D.A., Ravel J., Oekstad O.A., Helgason E., Cer R.Z., Jiang L., Shores K.A., Fouts D.E., Tourasse N.J., Angiuoli S.V., Kolonay J.F., Nelson W.C., Kolstoe A.-B., Fraser C.M., Read T.D. Nucleic Acids Res. 32:977-988(2004) [PubMed: 14960714] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 10987.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE017194 Genomic DNA. Translation: AAS39093.1.
RefSeq	NP_976485.1. NC_003909.8.
3D structure databases
ProteinModelPortal	Q73F50.
ModBase	Search...
Protein-protein interaction databases
STRING	Q73F50.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBBACT00000027863; EBBACP00000027213; EBBACG00000027854.
GeneID	2749790.
GenomeReviews	Gene locus BCE_0157 in contig AE017194_GR.
KEGG	bca:BCE_0157.
NMPDR	fig|222523.1.peg.157.
PATRIC	18849158. VBIBacCer118379_0151.
TIGR	BCE_0157.
Phylogenomic databases
eggNOG	COG1109.
GeneTree	EBGT00070000032132.
HOGENOM	HBG644964.
OMA	PLEDIQV.
ProtClustDB	PRK14316.
Enzyme and pathway databases
BioCyc	BCER405917:BCE_0157-MONOMER.
Family and domain databases
HAMAP	MF_01554_B. GlmM_B. [Tree]
InterPro	IPR005844. A-D-PHexomutase_a/b/a-I. IPR016055. A-D-PHexomutase_a/b/a-I/II/III. IPR005845. A-D-PHexomutase_a/b/a-II. IPR005846. A-D-PHexomutase_a/b/a-III. IPR005843. A-D-PHexomutase_C. IPR016066. A-D-PHexomutase_CS. IPR005841. Alpha-D-phosphohexomutase_SF. IPR006352. GlmM. [Graphical view]
Gene3D	G3DSA:3.40.120.10. A-D-PHexomutase_a/b/a-I/II/III. 3 hits.
KO	K03431.
Pfam	PF02878. PGM_PMM_I. 1 hit. PF02879. PGM_PMM_II. 1 hit. PF02880. PGM_PMM_III. 1 hit. PF00408. PGM_PMM_IV. 1 hit. [Graphical view]
PRINTS	PR00509. PGMPMM.
SUPFAM	SSF53738. A-D-PHexomutase_a/b/a-I/II/III. 3 hits.
TIGRFAMs	TIGR01455. GlmM. 1 hit.
PROSITE	PS00710. PGM_PMM. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GLMM_BACC1

Accession

Primary (citable) accession number: Q73F50

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 20, 2005
Last sequence update:	July 5, 2004
Last modified:	January 25, 2012
This is version 56 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program