Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q73F49

- GLMS_BACC1

UniProt

Q73F49 - GLMS_BACC1

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Glutamine--fructose-6-phosphate aminotransferase [isomerizing]

Gene

glmS

Organism
Bacillus cereus (strain ATCC 10987)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.UniRule annotation

Catalytic activityi

L-glutamine + D-fructose 6-phosphate = L-glutamate + D-glucosamine 6-phosphate.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei2 – 21Nucleophile; for GATase activityUniRule annotation
Active sitei595 – 5951For Fru-6P isomerization activityUniRule annotation

GO - Molecular functioni

  1. carbohydrate binding Source: InterPro
  2. glutamine-fructose-6-phosphate transaminase (isomerizing) activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbohydrate biosynthetic process Source: InterPro
  2. glutamine metabolic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Aminotransferase, Transferase

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]UniRule annotation (EC:2.6.1.16UniRule annotation)
Alternative name(s):
D-fructose-6-phosphate amidotransferaseUniRule annotation
GFATUniRule annotation
Glucosamine-6-phosphate synthaseUniRule annotation
Hexosephosphate aminotransferaseUniRule annotation
L-glutamine--D-fructose-6-phosphate amidotransferaseUniRule annotation
Gene namesi
Name:glmSUniRule annotation
Ordered Locus Names:BCE_0158
OrganismiBacillus cereus (strain ATCC 10987)
Taxonomic identifieri222523 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillusBacillus cereus group
ProteomesiUP000002527: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methioninei1 – 11RemovedUniRule annotation
Chaini2 – 600599Glutamine--fructose-6-phosphate aminotransferase [isomerizing]PRO_0000135294Add
BLAST

Interactioni

Subunit structurei

Homodimer.UniRule annotation

Protein-protein interaction databases

STRINGi222523.BCE_0158.

Structurei

3D structure databases

ProteinModelPortaliQ73F49.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini2 – 217216Glutamine amidotransferase type-2UniRule annotationAdd
BLAST
Domaini283 – 422140SIS 1UniRule annotationAdd
BLAST
Domaini452 – 590139SIS 2UniRule annotationAdd
BLAST

Sequence similaritiesi

Contains 1 glutamine amidotransferase type-2 domain.UniRule annotation
Contains 2 SIS domains.UniRule annotation

Keywords - Domaini

Glutamine amidotransferase, Repeat

Phylogenomic databases

eggNOGiCOG0449.
HOGENOMiHOG000258896.
KOiK00820.
OMAiSVFETQT.
OrthoDBiEOG6KT2Q1.

Family and domain databases

Gene3Di3.60.20.10. 1 hit.
HAMAPiMF_00164. GlmS.
InterProiIPR017932. GATase_2_dom.
IPR000583. GATase_dom.
IPR005855. GlmS_trans.
IPR029055. Ntn_hydrolases_N.
IPR001347. SIS.
[Graphical view]
PANTHERiPTHR10937:SF0. PTHR10937:SF0. 1 hit.
PfamiPF00310. GATase_2. 1 hit.
PF01380. SIS. 2 hits.
[Graphical view]
SUPFAMiSSF56235. SSF56235. 1 hit.
TIGRFAMsiTIGR01135. glmS. 1 hit.
PROSITEiPS51278. GATASE_TYPE_2. 1 hit.
PS51464. SIS. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q73F49-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MCGIVGFIGE QDAKEILLKG LEKLEYRGYD SAGIAVQAEN GVVVYKEKGR
60 70 80 90 100
IAKLREIVDE NVATSVGIGH TRWATHGVPS KVNAHPHQST SKRFTLVHNG
110 120 130 140 150
VIENYELVKK EYLQDVTFVS ETDTEVIVQL MEQQVSTGLS VEEAFRNTLS
160 170 180 190 200
LLHGSYAIGL LDAENPNMIY VAKNKSPLLV GVGDNFNVVA SDAMAMLQVT
210 220 230 240 250
DQFIELMDKE IVIVTKESIT IKNLQGETIE RAPFTAELDA SDIEKGTYPH
260 270 280 290 300
FMLKEIDEQP LVIRNIIQKY QDENGEIELD QDIRNAILDS DRIYIIACGT
310 320 330 340 350
SYHAGLVGKQ FIEKFAKMPV EVHVASEFSY NMPLLTERPF FIYISQSGET
360 370 380 390 400
ADSRAVLVQT NEMGHKALTI TNVPGSTLSR EADYTLPLYA GPEIAVASTK
410 420 430 440 450
AYTAQLAVLS ILAADIAKAK GEVLGFDLTH ELGLVANAMV QLCDQKEEMD
460 470 480 490 500
ALAKQFLATT RNCFFIGRSV DFYVGLEGAL KLKEISYIQA EGFAGGELKH
510 520 530 540 550
GTIALIENGT PVIALATQEH VNLGIRGNVK EVVARGANPC IISMKGLEME
560 570 580 590 600
GDSFVLPAVH EALAPLVAVI PLQLISYYAA LHRECDVDKP RNLAKSVTVE
Length:600
Mass (Da):65,750
Last modified:January 23, 2007 - v3
Checksum:iCF9D5EDB164B7892
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017194 Genomic DNA. Translation: AAS39094.1.
RefSeqiNP_976486.1. NC_003909.8.

Genome annotation databases

EnsemblBacteriaiAAS39094; AAS39094; BCE_0158.
GeneIDi2748273.
KEGGibca:BCE_0158.
PATRICi18849162. VBIBacCer118379_0153.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017194 Genomic DNA. Translation: AAS39094.1 .
RefSeqi NP_976486.1. NC_003909.8.

3D structure databases

ProteinModelPortali Q73F49.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 222523.BCE_0158.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAS39094 ; AAS39094 ; BCE_0158 .
GeneIDi 2748273.
KEGGi bca:BCE_0158.
PATRICi 18849162. VBIBacCer118379_0153.

Phylogenomic databases

eggNOGi COG0449.
HOGENOMi HOG000258896.
KOi K00820.
OMAi SVFETQT.
OrthoDBi EOG6KT2Q1.

Family and domain databases

Gene3Di 3.60.20.10. 1 hit.
HAMAPi MF_00164. GlmS.
InterProi IPR017932. GATase_2_dom.
IPR000583. GATase_dom.
IPR005855. GlmS_trans.
IPR029055. Ntn_hydrolases_N.
IPR001347. SIS.
[Graphical view ]
PANTHERi PTHR10937:SF0. PTHR10937:SF0. 1 hit.
Pfami PF00310. GATase_2. 1 hit.
PF01380. SIS. 2 hits.
[Graphical view ]
SUPFAMi SSF56235. SSF56235. 1 hit.
TIGRFAMsi TIGR01135. glmS. 1 hit.
PROSITEi PS51278. GATASE_TYPE_2. 1 hit.
PS51464. SIS. 2 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The genome sequence of Bacillus cereus ATCC 10987 reveals metabolic adaptations and a large plasmid related to Bacillus anthracis pXO1."
    Rasko D.A., Ravel J., Oekstad O.A., Helgason E., Cer R.Z., Jiang L., Shores K.A., Fouts D.E., Tourasse N.J., Angiuoli S.V., Kolonay J.F., Nelson W.C., Kolstoe A.-B., Fraser C.M., Read T.D.
    Nucleic Acids Res. 32:977-988(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 10987.

Entry informationi

Entry nameiGLMS_BACC1
AccessioniPrimary (citable) accession number: Q73F49
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 30, 2005
Last sequence update: January 23, 2007
Last modified: October 29, 2014
This is version 75 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3