Q73ES6 (GCP_BACC1) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable tRNA threonylcarbamoyladenosine biosynthesis protein Gcp

Alternative name(s):
t(6)A37 threonylcarbamoyladenosine biosynthesis protein

Gene names

Name:	gcp
Ordered Locus Names:	BCE_0282

Organism

Bacillus cereus (strain ATCC 10987) [Complete proteome] [HAMAP]

Taxonomic identifier

222523 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus › Bacillus cereus group

Protein attributes

Sequence length	343 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t6A37) in tRNAs that read codons beginning with adenine By similarity. HAMAP MF_01445
Subcellular location	Cytoplasm Potential HAMAP MF_01445.
Sequence similarities	Belongs to the KAE1 / YgjD family.
Sequence caution	The sequence AAS39218.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
Biological process	tRNA processing
Cellular component	Cytoplasm
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	proteolysis Inferred from electronic annotation. Source: InterPro tRNA processing Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	metalloendopeptidase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 343	343	Probable tRNA threonylcarbamoyladenosine biosynthesis protein Gcp HAMAP MF_01445		PRO_0000303263

Sequences

	Sequence		Length	Mass (Da)
	Q73ES6 [UniParc]. Last modified September 11, 2007. Version 2. Checksum: 1866E3F8A4E036A4	FASTA	343	36,538
	10 20 30 40 50 60 MGEYIMEKNT IILGIETSCD ETAVAVVKNG TEIIANVVAS QIESHKRFGG VVPEIASRHH 70 80 90 100 110 120 VEEITVVLEE ALKEANITFD DIDAIAVTEG PGLVGALLIG VNAAKAVAFA HDIPLVGVHH 130 140 150 160 170 180 IAGHIYANRL VKEVQFPLLS LVVSGGHTEL VYMKEHGSFE VIGETRDDAA GEAYDKVART 190 200 210 220 230 240 LSMPYPGGPH IDRLAHEGEP TIDLPRAWLE PDSYDFSFSG LKSAVINTVH NAKQRGIEIA 250 260 270 280 290 300 PEDLAASFQE SVIDVLVTKA SRAADAYNVK QVLLAGGVAA NKGLRARLEA EFAQKENVEL 310 320 330 340 IIPPLSLCTD NAAMIAAAGT IAYEQGKRAT LALNANPGLD IEA

References

[1]

"The genome sequence of Bacillus cereus ATCC 10987 reveals metabolic adaptations and a large plasmid related to Bacillus anthracis pXO1." Rasko D.A., Ravel J., Oekstad O.A., Helgason E., Cer R.Z., Jiang L., Shores K.A., Fouts D.E., Tourasse N.J., Angiuoli S.V., Kolonay J.F., Nelson W.C., Kolstoe A.-B., Fraser C.M., Read T.D. Nucleic Acids Res. 32:977-988(2004) [PubMed: 14960714] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 10987.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE017194 Genomic DNA. Translation: AAS39218.1. Different initiation.
RefSeq	NP_976610.1. NC_003909.8.
3D structure databases
ProteinModelPortal	Q73ES6.
ModBase	Search...
Protein-protein interaction databases
STRING	Q73ES6.
Protein family/group databases
MEROPS	M22.A01.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBBACT00000028300; EBBACP00000027650; EBBACG00000028291.
GeneID	2752649.
GenomeReviews	Gene locus BCE_0282 in contig AE017194_GR.
KEGG	bca:BCE_0282.
NMPDR	fig|222523.1.peg.282.
PATRIC	18849434. VBIBacCer118379_0276.
TIGR	BCE_0282.
Phylogenomic databases
eggNOG	COG0533.
GeneTree	EBGT00050000002496.
HOGENOM	HBG304663.
ProtClustDB	PRK09604.
Enzyme and pathway databases
BioCyc	BCER405917:BCE_0282-MONOMER.
Family and domain databases
HAMAP	MF_01445. gcp. [Tree]
InterPro	IPR022450. Pept_M22_O-sialoglycopept. IPR000905. Peptidase_M22. IPR017860. Peptidase_M22_CS. IPR017861. Peptidase_M22_subgr. [Graphical view]
KO	K01409.
Pfam	PF00814. Peptidase_M22. 1 hit. [Graphical view]
PRINTS	PR00789. OSIALOPTASE.
TIGRFAMs	TIGR03723. Bact_gcp. 1 hit. TIGR00329. Gcp_kae1. 1 hit.
PROSITE	PS01016. GLYCOPROTEASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GCP_BACC1

Accession

Primary (citable) accession number: Q73ES6

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 11, 2007
Last sequence update:	September 11, 2007
Last modified:	January 25, 2012
This is version 52 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program