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Protein

Uncharacterized RNA methyltransferase BCE_0363

Gene

BCE_0363

Organism
Bacillus cereus (strain ATCC 10987 / NRS 248)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi79 – 791Iron-sulfur (4Fe-4S)By similarity
Metal bindingi85 – 851Iron-sulfur (4Fe-4S)By similarity
Metal bindingi88 – 881Iron-sulfur (4Fe-4S)By similarity
Metal bindingi166 – 1661Iron-sulfur (4Fe-4S)By similarity
Binding sitei290 – 2901S-adenosyl-L-methioninePROSITE-ProRule annotation
Binding sitei319 – 3191S-adenosyl-L-methionine; via carbonyl oxygenPROSITE-ProRule annotation
Binding sitei340 – 3401S-adenosyl-L-methioninePROSITE-ProRule annotation
Binding sitei388 – 3881S-adenosyl-L-methioninePROSITE-ProRule annotation
Active sitei415 – 4151NucleophilePROSITE-ProRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Methyltransferase, Transferase

Keywords - Ligandi

4Fe-4S, Iron, Iron-sulfur, Metal-binding, S-adenosyl-L-methionine

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized RNA methyltransferase BCE_0363 (EC:2.1.1.-)
Gene namesi
Ordered Locus Names:BCE_0363
OrganismiBacillus cereus (strain ATCC 10987 / NRS 248)
Taxonomic identifieri222523 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillusBacillus cereus group
Proteomesi
  • UP000002527 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 460460Uncharacterized RNA methyltransferase BCE_0363PRO_0000161948Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliQ73EJ5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini8 – 6659TRAMPROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.PROSITE-ProRule annotation
Contains 1 TRAM domain.PROSITE-ProRule annotation

Phylogenomic databases

HOGENOMiHOG000029867.
KOiK03215.
OMAiWGEEYIY.

Family and domain databases

Gene3Di2.40.50.140. 1 hit.
3.40.50.150. 1 hit.
InterProiIPR001566. 23S_rRNA_MeTrfase_RlmD.
IPR030382. MeTrfase_TRM5/TYW2.
IPR030390. MeTrfase_TrmA_AS.
IPR030391. MeTrfase_TrmA_CS.
IPR012340. NA-bd_OB-fold.
IPR029063. SAM-dependent_MTases.
IPR002792. TRAM_dom.
IPR010280. U5_MeTrfase_fam.
[Graphical view]
PfamiPF02475. Met_10. 1 hit.
PF01938. TRAM. 1 hit.
PF05958. tRNA_U5-meth_tr. 1 hit.
[Graphical view]
SUPFAMiSSF50249. SSF50249. 1 hit.
SSF53335. SSF53335. 1 hit.
TIGRFAMsiTIGR00479. rumA. 1 hit.
PROSITEiPS51687. SAM_MT_RNA_M5U. 1 hit.
PS50926. TRAM. 1 hit.
PS01230. TRMA_1. 1 hit.
PS01231. TRMA_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q73EJ5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSTKMTPPVE KNEFIDVVFE DLTHDGAGVA KVKGYPIFVK NGLPGEEAQI
60 70 80 90 100
KIIKVKKNFA FGRLMKLHTE SPYRKDAECP VYNQCGGCQL QHLTYEGQLQ
110 120 130 140 150
AKEKQVRDVM QRIGGLSDVP VHPVLGMKNP WVYRNKAQVP IGEREGGLVA
160 170 180 190 200
GFYRQGTHDI INMESCLIQA EENDTLIQEV KRICEKHGIS AYNEERNKGT
210 220 230 240 250
LRHVMARYGQ VTGEIMLVFI TRTAELPNKK AIIEEIATKF PEVKSIVQNV
260 270 280 290 300
NPKRTNVIFG DKTTVLYGSE YIYDFIGDIK FAISARSFYQ VNPEQTKVLY
310 320 330 340 350
DKTLEYAKLD GNETVIDAYC GIGSISLFLA QKAKKVYGVE IVPEAIEDAK
360 370 380 390 400
RNAALNNMTN AEFGVGEAEV VIPKWYKEGV IADTMVVDPP RKGCDEALLN
410 420 430 440 450
TIIDMKPKRV VYVSCNPATL ARDLKVLEEG GYKTQEVQPV DMFPHTTHVE
460
CVVLMSRVEK
Length:460
Mass (Da):51,618
Last modified:July 5, 2004 - v1
Checksum:iCDB4B9F7039EAFD3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017194 Genomic DNA. Translation: AAS39299.1.
RefSeqiWP_000105047.1. NC_003909.8.

Genome annotation databases

EnsemblBacteriaiAAS39299; AAS39299; BCE_0363.
KEGGibca:BCE_0363.
PATRICi18849604. VBIBacCer118379_0349.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017194 Genomic DNA. Translation: AAS39299.1.
RefSeqiWP_000105047.1. NC_003909.8.

3D structure databases

ProteinModelPortaliQ73EJ5.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAS39299; AAS39299; BCE_0363.
KEGGibca:BCE_0363.
PATRICi18849604. VBIBacCer118379_0349.

Phylogenomic databases

HOGENOMiHOG000029867.
KOiK03215.
OMAiWGEEYIY.

Family and domain databases

Gene3Di2.40.50.140. 1 hit.
3.40.50.150. 1 hit.
InterProiIPR001566. 23S_rRNA_MeTrfase_RlmD.
IPR030382. MeTrfase_TRM5/TYW2.
IPR030390. MeTrfase_TrmA_AS.
IPR030391. MeTrfase_TrmA_CS.
IPR012340. NA-bd_OB-fold.
IPR029063. SAM-dependent_MTases.
IPR002792. TRAM_dom.
IPR010280. U5_MeTrfase_fam.
[Graphical view]
PfamiPF02475. Met_10. 1 hit.
PF01938. TRAM. 1 hit.
PF05958. tRNA_U5-meth_tr. 1 hit.
[Graphical view]
SUPFAMiSSF50249. SSF50249. 1 hit.
SSF53335. SSF53335. 1 hit.
TIGRFAMsiTIGR00479. rumA. 1 hit.
PROSITEiPS51687. SAM_MT_RNA_M5U. 1 hit.
PS50926. TRAM. 1 hit.
PS01230. TRMA_1. 1 hit.
PS01231. TRMA_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiY363_BACC1
AccessioniPrimary (citable) accession number: Q73EJ5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 16, 2004
Last sequence update: July 5, 2004
Last modified: September 7, 2016
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.