Reviewed,
UniProtKB/Swiss-Prot Q73AX8 (AROB_BACC1)
Last modified
November 3, 2009.
Version 39.
History...
Clusters with 100%,
90%,
50% identity |
Documents (2) |
Third-party data |
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Names and origin
| Protein names | Recommended name: 3-dehydroquinate synthase EC=4.2.3.4 | ||||
| Gene names |
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| Organism | Bacillus cereus (strain ATCC 10987) [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 222523 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus › Bacillus cereus group |
Protein attributes
| Sequence length | 361 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Inferred from homology. |
General annotation (Comments)
| Catalytic activity | 3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate = 3-dehydroquinate + phosphate. HAMAP MF_00110 |
| Cofactor | Divalent metal cations By similarity. NAD By similarity. |
| Pathway | Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 2/7. HAMAP MF_00110 |
| Subunit structure | Monomer By similarity. |
| Subcellular location | Cytoplasm Probable. |
| Sequence similarities | Belongs to the dehydroquinate synthase family. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Amino-acid biosynthesis Aromatic amino acid biosynthesis |
| Cellular component | Cytoplasm |
| Ligand | NAD |
| Molecular function | Lyase |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | aromatic amino acid family biosynthetic process Inferred from electronic annotation. Source: HAMAP |
| Cellular component | cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell |
| Molecular function | 3-dehydroquinate synthase activity Inferred from electronic annotation. Source: HAMAP |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||
Molecule processing | |||||||
|---|---|---|---|---|---|---|---|
| Chain | 1 – 361 | 361 | 3-dehydroquinate synthase HAMAP MF_00110 | PRO_0000231063 | |||
Sequences
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References
| [1] | "The genome sequence of Bacillus cereus ATCC 10987 reveals metabolic adaptations and a large plasmid related to Bacillus anthracis pXO1." Rasko D.A., Ravel J., Oekstad O.A., Helgason E., Cer R.Z., Jiang L., Shores K.A., Fouts D.E., Tourasse N.J., Angiuoli S.V., Kolonay J.F., Nelson W.C., Kolstoe A.-B., Fraser C.M., Read T.D. Nucleic Acids Res. 32:977-988(2004) [PubMed: 14960714] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. |
Cross-references
Sequence databases | |
|---|---|
| AE017194 Genomic DNA. Translation: AAS40573.1. | |
| RefSeq | NP_977965.1. |
3D structure databases | |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | Q73AX8. |
Genome annotation databases | |
| GeneID | 2750267. |
| GenomeReviews | Gene locus BCE_1644 in contig AE017194_GR. |
| KEGG | bca:BCE_1644. |
| NMPDR | fig|222523.1.peg.1637. |
| TIGR | BCE_1644. |
Phylogenomic databases | |
| HOGENOM | Q73AX8. |
| OMA | KANIVAQ. |
Family and domain databases | |
| HAMAP | MF_00110. [Tree] |
| InterPro | IPR016303. DHQ_synth. IPR002658. DHQ_synth_AroB. IPR016037. DHQ_synth_AroB_sub. [Graphical view] |
| PANTHER | PTHR21090:SF1. DHQ_synth_AroB. 1 hit. |
| Pfam | PF01761. DHQ_synthase. 1 hit. [Graphical view] |
| PIRSF | PIRSF001455. DHQ_synth. 1 hit. |
| TIGRFAMs | TIGR01357. aroB. 1 hit. |
| ProtoNet | Search... |
Entry information
| Entry name | AROB_BACC1 | ||||||||
| Accession | Primary (citable) accession number: Q73AX8 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes) | ||||||||
Relevant documents
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

Clusters with


