Q73A51 (Q73A51_BACC1) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Peptide methionine sulfoxide reductase MsrA HAMAP MF_01401
Short name=Protein-methionine-S-oxide reductase HAMAP MF_01401
EC=1.8.4.11 HAMAP MF_01401

Alternative name(s):
Peptide-methionine (S)-S-oxide reductase HAMAP MF_01401

Gene names

Name:	msrA HAMAP MF_01401
Ordered Locus Names:	BCE_1931

Organism

Bacillus cereus (strain ATCC 10987) [Complete proteome] [HAMAP] EMBL AAS40855.1

Taxonomic identifier

222523 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus › Bacillus cereus group

Protein attributes

Sequence length	178 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine By similarity. HAMAP MF_01401
Catalytic activity	L-methionine + thioredoxin disulfide + H2O = L-methionine (S)-S-oxide + thioredoxin. HAMAP MF_01401 Peptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (S)-S-oxide + thioredoxin. HAMAP MF_01401
Sequence similarities	Belongs to the MsrA Met sulfoxide reductase family. HAMAP MF_01401

Ontologies

Keywords
Molecular function	Oxidoreductase HAMAP MF_01401 EMBL AAS40855.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	protein modification process Inferred from electronic annotation. Source: HAMAP
Molecular function	peptide-methionine-(S)-S-oxide reductase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	15	1	By similarity HAMAP MF_01401

Sequences

	Sequence		Length	Mass (Da)
	Q73A51 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: 4122B15058C40FDF	FASTA	178	20,605
	10 20 30 40 50 60 MSEKTYELAT FAGGCFWCMV KPFDELPGIH KVRSGYAGGH VENPTYEQVK AGTSGHLEVV 70 80 90 100 110 120 QITFDPSIFP YKKLLDLYWP QIDPTDDGGQ FFDRGPSYRT AIFYHNETQK ELAEKSKQAL 130 140 150 160 170 AESGMFKEPI VTEIRPAAPF YEAEEYHQHF YKKNPEKYAT EQKESGREDF IKENWQKK

References

[1]

"The genome sequence of Bacillus cereus ATCC 10987 reveals metabolic adaptations and a large plasmid related to Bacillus anthracis pXO1." Rasko D.A., Ravel J., Oekstad O.A., Helgason E., Cer R.Z., Jiang L., Shores K.A., Fouts D.E., Tourasse N.J., Angiuoli S.V., Kolonay J.F., Nelson W.C., Kolstoe A.-B., Fraser C.M., Read T.D. Nucleic Acids Res. 32:977-988(2004) [PubMed: 14960714] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE017194 Genomic DNA. Translation: AAS40855.1.
RefSeq	NP_978247.1. NC_003909.8.
3D structure databases
ProteinModelPortal	Q73A51.
ModBase	Search...
Protein-protein interaction databases
STRING	Q73A51.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBBACT00000027716; EBBACP00000027066; EBBACG00000027707.
GeneID	2748609.
GenomeReviews	Gene locus BCE_1931 in contig AE017194_GR.
KEGG	bca:BCE_1931.
NMPDR	fig|222523.1.peg.1919.
PATRIC	18852682. VBIBacCer118379_1844.
TIGR	BCE_1931.
Phylogenomic databases
eggNOG	COG0225.
GeneTree	EBGT00050000000580.
HOGENOM	HBG748152.
OMA	LVELYWT.
ProtClustDB	CLSK916383.
Family and domain databases
HAMAP	MF_01401. MsrA. [Tree]
InterPro	IPR002569. Peptide_Met_Sox_Rdtase_MsrA. [Graphical view]
Gene3D	G3DSA:3.30.1060.10. MsrA. 1 hit.
KO	K07304.
Pfam	PF01625. PMSR. 1 hit. [Graphical view]
SUPFAM	SSF55068. MsrA. 1 hit.
TIGRFAMs	TIGR00401. MsrA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q73A51_BACC1

Accession

Primary (citable) accession number: Q73A51

Entry history

Integrated into UniProtKB/TrEMBL:	July 5, 2004
Last sequence update:	July 5, 2004
Last modified:	December 14, 2011
This is version 59 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)