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Reviewed, UniProtKB/Swiss-Prot Q739D2 (XYLA_BACC1)

Last modified November 3, 2009. Version 39. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

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Names and origin

Protein namesRecommended name:
    Xylose isomerase
    EC=5.3.1.5
Gene names
Name: xylA
Ordered Locus Names: BCE_2210
OrganismBacillus cereus (strain ATCC 10987) [Complete proteome] [HAMAP]
Taxonomic identifier222523 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus › Bacillus cereus group

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Protein attributes

Sequence length445 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

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General annotation (Comments)

Catalytic activity

D-xylose = D-xylulose. HAMAP MF_00455

Cofactor

Binds 2 magnesium ions per subunit By similarity.

Subunit structure

Homotetramer By similarity.

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the xylose isomerase family.

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Ontologies

Keywords
   Biological processCarbohydrate metabolism
Pentose shunt
Xylose metabolism
   Cellular componentCytoplasm
   LigandMagnesium
Metal-binding
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processD-xylose metabolic process

Inferred from electronic annotation. Source: HAMAP

pentose-phosphate shunt

Inferred from electronic annotation. Source: HAMAP

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionmagnesium ion binding

Inferred from electronic annotation. Source: HAMAP

xylose isomerase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 445445Xylose isomerase HAMAP MF_00455
PRO_0000195761

Sites

Active site1071 By similarity
Active site1101 By similarity
Metal binding2381Magnesium 1 By similarity
Metal binding2741Magnesium 1 By similarity
Metal binding2741Magnesium 2 By similarity
Metal binding2771Magnesium 2 By similarity
Metal binding3021Magnesium 1 By similarity
Metal binding3131Magnesium 2 By similarity
Metal binding3151Magnesium 2 By similarity
Metal binding3451Magnesium 1 By similarity

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Sequences

Sequence LengthMass (Da)Tools
Q739D2-1 [UniParc].

Last modified July 5, 2004. Version 1.
Checksum: 3582F281E85CDCB8

FASTA44550,322
        10         20         30         40         50         60 
MAQSSTNKVS YFESVNKVLY EGKGSKNPLA FKYYNPEEIV GDKTMKEQLR FSIAYWHTFT 

        70         80         90        100        110        120 
ADGTDPFGAA TMQRAWDKYD GMDLAKARVE AAFQLFEKLN VPFFAFHDRD IAPEGSTLRE 

       130        140        150        160        170        180 
TNKNLDVIVT MIKDYMKTSN VKLLWNTANM FTNPRFVHGA ATSCNADVFA YAAAQVKKGL 

       190        200        210        220        230        240 
ETAKELGAEN YVFWGGREGY DTLLNTNLKL ELDNLARFMQ MSVDYAKEIG YTGQFLIEPK 

       250        260        270        280        290        300 
PKEPTTHQYD TDAATTISFL RQYGLENHFK LNLEANHATL AGHTFEHELR VARVQGFLGS 

       310        320        330        340        350        360 
VDANQGNPLL GWDTDEFPTN LYSTTLAMYE ILQNGGLGSG GLNFDAKVRR ASFEEEDLVY 

       370        380        390        400        410        420 
AHIAGMDAFA RGLKVAHKLL EDRVFENIID ERYHSFRDGI GLEIVEGRAN FHTLEQYALQ 

       430        440 
NSIIKNQSGK QERLKAILNQ YILEV

« Hide

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References

[1]"The genome sequence of Bacillus cereus ATCC 10987 reveals metabolic adaptations and a large plasmid related to Bacillus anthracis pXO1."
Rasko D.A., Ravel J., Oekstad O.A., Helgason E., Cer R.Z., Jiang L., Shores K.A., Fouts D.E., Tourasse N.J., Angiuoli S.V., Kolonay J.F., Nelson W.C., Kolstoe A.-B., Fraser C.M., Read T.D.
Nucleic Acids Res. 32:977-988(2004) [PubMed: 14960714] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

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Cross-references

Sequence databases

AE017194 Genomic DNA. Translation: AAS41130.1.
RefSeqNP_978522.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGQ739D2.

Genome annotation databases

GeneID2749971.
GenomeReviewsGene locus BCE_2210 in contig AE017194_GR.
KEGGbca:BCE_2210.
NMPDRfig|222523.1.peg.2194.
TIGRBCE_2210.

Phylogenomic databases

HOGENOMQ739D2.
OMAQFLIEPK.

Family and domain databases

HAMAPMF_00455.
[Tree]
InterProIPR013022. Xyl_isomerase-like_TIM-brl.
IPR012307. Xyl_isomerase_TIM-brl.
IPR013452. Xylose_isom_bac.
IPR001998. Xylose_isomerase.
IPR018115. Xylose_isomerase_AS.
[Graphical view]
Gene3DG3DSA:3.20.20.150. Xyl_isomerase-like_TIM-brl. 1 hit.
PfamPF01261. AP_endonuc_2. 1 hit.
[Graphical view]
PRINTSPR00688. XYLOSISMRASE.
TIGRFAMsTIGR02630. xylose_isom_A. 1 hit.
PROSITEPS51415. XYLOSE_ISOMERASE. 1 hit.
[Graphical view]
ProtoNetSearch...

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Entry information

Entry nameXYLA_BACC1
AccessionPrimary (citable) accession number: Q739D2
Entry history
Integrated into UniProtKB/Swiss-Prot: July 19, 2004
Last sequence update: July 5, 2004
Last modified: November 3, 2009
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

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Relevant documents

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents