Q732Z5 (GPMA2_BACC1) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase 2
Short name=BPG-dependent PGAM 2
Short name=PGAM 2
Short name=Phosphoglyceromutase 2
Short name=dPGM 2
EC=5.4.2.1

Gene names

Name:	gpmA2
Ordered Locus Names:	BCE_3765

Organism

Bacillus cereus (strain ATCC 10987) [Complete proteome] [HAMAP]

Taxonomic identifier

222523 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus › Bacillus cereus group

Protein attributes

Sequence length	240 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate By similarity. HAMAP MF_01039
Catalytic activity	2-phospho-D-glycerate = 3-phospho-D-glycerate. HAMAP MF_01039
Pathway	Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 3/5. HAMAP MF_01039
Sequence similarities	Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.

Ontologies

Keywords
Biological process	Glycolysis
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycolysis Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	phosphoglycerate mutase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 240	240	2,3-bisphosphoglycerate-dependent phosphoglycerate mutase 2 HAMAP MF_01039		PRO_0000179844
Sites
	Active site	9	1	Tele-phosphohistidine intermediate By similarity
	Active site	182	1	By similarity
	Site	60	1	Interaction with carboxyl group of phosphoglycerates By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q732Z5 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: F59901F112313FB0	FASTA	240	27,968
	10 20 30 40 50 60 MVKLVLIRHG QSEWNVENRF TGWTDVDLSS KGLEEAREAG VMLKASGFSF DIAYTSVLRR 70 80 90 100 110 120 AMRTLWITLE EMDLMWIPVY KTWKLNERHY GALQGLNKEE TARKYGDEQV TLWRRSTNVR 130 140 150 160 170 180 PPALTKDDER YEAAHPKYRD IKDYEFPLTE DLEDTEKRVV SYWNEEIAPN VKAGKQVIIA 190 200 210 220 230 240 AHGNTIRALV KHLDQISDKD IENVNIPTGT PLVYELDNDL KPIGHYYLNR EIETLEEKQV

References

[1]

"The genome sequence of Bacillus cereus ATCC 10987 reveals metabolic adaptations and a large plasmid related to Bacillus anthracis pXO1." Rasko D.A., Ravel J., Oekstad O.A., Helgason E., Cer R.Z., Jiang L., Shores K.A., Fouts D.E., Tourasse N.J., Angiuoli S.V., Kolonay J.F., Nelson W.C., Kolstoe A.-B., Fraser C.M., Read T.D. Nucleic Acids Res. 32:977-988(2004) [PubMed: 14960714] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 10987.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE017194 Genomic DNA. Translation: AAS42670.1.
RefSeq	NP_980062.1. NC_003909.8.
3D structure databases
ProteinModelPortal	Q732Z5.
SMR	Q732Z5. Positions 1-233.
ModBase	Search...
Protein-protein interaction databases
STRING	Q732Z5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBBACT00000025403; EBBACP00000024753; EBBACG00000025394.
GeneID	2752317.
GenomeReviews	Gene locus BCE_3765 in contig AE017194_GR.
KEGG	bca:BCE_3765.
NMPDR	fig|222523.1.peg.3734.
PATRIC	18856194. VBIBacCer118379_3596.
TIGR	BCE_3765.
Phylogenomic databases
eggNOG	COG0588.
GeneTree	EBGT00050000001820.
HOGENOM	HBG658938.
OMA	YWNDVII.
Enzyme and pathway databases
BioCyc	BCER405917:BCE_3765-MONOMER.
Family and domain databases
HAMAP	MF_01039. PGAM_GpmA. [Tree]
InterPro	IPR013078. His_Pase_superF_clade-1. IPR001345. PG/BPGM_mutase_AS. IPR005952. Phosphogly_mut1. [Graphical view]
KO	K01834.
PANTHER	PTHR11931. Phosphogly_mut1. 1 hit.
Pfam	PF00300. His_Phos_1. 1 hit. [Graphical view]
SMART	SM00855. PGAM. 1 hit. [Graphical view]
TIGRFAMs	TIGR01258. Pgm_1. 1 hit.
PROSITE	PS00175. PG_MUTASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GPMA2_BACC1

Accession

Primary (citable) accession number: Q732Z5

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 19, 2004
Last sequence update:	July 5, 2004
Last modified:	January 25, 2012
This is version 54 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program