Q732K3 (Q732K3_BACC1) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Peptide deformylase 1 HAMAP MF_00163
Short name=PDF 1 HAMAP MF_00163
EC=3.5.1.88 HAMAP MF_00163

Alternative name(s):
Polypeptide deformylase 1 HAMAP MF_00163

Gene names

Name:	deF EMBL AAS42814.1
Synonyms:	def1 HAMAP MF_00163
Ordered Locus Names:	BCE_3910

Organism

Bacillus cereus (strain ATCC 10987) [Complete proteome] [HAMAP] EMBL AAS42814.1

Taxonomic identifier

222523 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus › Bacillus cereus group

Protein attributes

Sequence length	156 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions By similarity. HAMAP MF_00163
Catalytic activity	Formyl-L-methionyl peptide + H2O = formate + methionyl peptide. HAMAP MF_00163 SAAS SAAS000181
Cofactor	Binds 1 Fe2+ ion By similarity. HAMAP MF_00163
Sequence similarities	Belongs to the polypeptide deformylase family. HAMAP MF_00163

Ontologies

Keywords
Biological process	Protein biosynthesis HAMAP MF_00163 SAAS SAAS000181
Ligand	Iron HAMAP MF_00163 Metal-binding SAAS SAAS000181 HAMAP MF_00163
Molecular function	Hydrolase HAMAP MF_00163 SAAS SAAS000181 EMBL AAS42814.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	translation Inferred from electronic annotation. Source: HAMAP
Molecular function	iron ion binding Inferred from electronic annotation. Source: InterPro peptide deformylase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	133	1	By similarity HAMAP MF_00163
	Metal binding	90	1	Iron By similarity HAMAP MF_00163
	Metal binding	132	1	Iron By similarity HAMAP MF_00163
	Metal binding	136	1	Iron By similarity HAMAP MF_00163

Sequences

	Sequence		Length	Mass (Da)
	Q732K3 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: ED6ED75C2A963C8D	FASTA	156	17,422
	10 20 30 40 50 60 MAVLEIVKHP NEVLETPCER VINFDKKLVK LLKDMHETML IADGVGLAAP QVGVSLQVAV 70 80 90 100 110 120 VDIGDDTGKI ELINPSILEK RGEQVGPEGC LSFPGLYGEV ERADYIKVRA QNRRGKVFLL 130 140 150 EAEGFLARAI QHEIDHLHGV LFTSKVTRYY EENELE

References

[1]

"The genome sequence of Bacillus cereus ATCC 10987 reveals metabolic adaptations and a large plasmid related to Bacillus anthracis pXO1." Rasko D.A., Ravel J., Oekstad O.A., Helgason E., Cer R.Z., Jiang L., Shores K.A., Fouts D.E., Tourasse N.J., Angiuoli S.V., Kolonay J.F., Nelson W.C., Kolstoe A.-B., Fraser C.M., Read T.D. Nucleic Acids Res. 32:977-988(2004) [PubMed: 14960714] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE017194 Genomic DNA. Translation: AAS42814.1.
RefSeq	NP_980206.1. NC_003909.8.
3D structure databases
ProteinModelPortal	Q732K3.
SMR	Q732K3. Positions 1-151.
ModBase	Search...
Protein-protein interaction databases
STRING	Q732K3.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBBACT00000026365; EBBACP00000025715; EBBACG00000026356.
GeneID	2750606.
GenomeReviews	Gene locus BCE_3910 in contig AE017194_GR.
KEGG	bca:BCE_3910.
PATRIC	18856476. VBIBacCer118379_3737.
TIGR	BCE_3910.
Phylogenomic databases
eggNOG	COG0242.
GeneTree	EBGT00050000001175.
HOGENOM	HBG665227.
OMA	RQLAKEM.
ProtClustDB	PRK12846.
Family and domain databases
HAMAP	MF_00163. Pep_deformylase. [Tree]
InterPro	IPR000181. Fmet_deformylase. IPR023635. Peptide_deformylase. [Graphical view]
Gene3D	G3DSA:3.90.45.10. Fmet_deformylase. 1 hit.
KO	K01462.
PANTHER	PTHR10458. Fmet_deformylase. 1 hit.
Pfam	PF01327. Pep_deformylase. 1 hit. [Graphical view]
PIRSF	PIRSF004749. Pep_def. 1 hit.
PRINTS	PR01576. PDEFORMYLASE.
SUPFAM	SSF56420. Fmet_deformylase. 1 hit.
TIGRFAMs	TIGR00079. Pept_deformyl. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q732K3_BACC1

Accession

Primary (citable) accession number: Q732K3

Entry history

Integrated into UniProtKB/TrEMBL:	July 5, 2004
Last sequence update:	July 5, 2004
Last modified:	December 14, 2011
This is version 50 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)