Q731Z2 (Q731Z2_BACC1) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Peptide deformylase 2 HAMAP MF_00163
Short name=PDF 2 HAMAP MF_00163
EC=3.5.1.88 HAMAP MF_00163

Alternative name(s):
Polypeptide deformylase 2 HAMAP MF_00163

Gene names

Name:	deF EMBL AAS42925.1
Synonyms:	def2 HAMAP MF_00163
Ordered Locus Names:	BCE_4023

Organism

Bacillus cereus (strain ATCC 10987) [Complete proteome] [HAMAP] EMBL AAS42925.1

Taxonomic identifier

222523 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus › Bacillus cereus group

Protein attributes

Sequence length	184 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions By similarity. HAMAP MF_00163
Catalytic activity	Formyl-L-methionyl peptide + H2O = formate + methionyl peptide. HAMAP MF_00163 SAAS SAAS000181
Cofactor	Binds 1 Fe2+ ion By similarity. HAMAP MF_00163
Sequence similarities	Belongs to the polypeptide deformylase family. HAMAP MF_00163

Ontologies

Keywords
Biological process	Protein biosynthesis HAMAP MF_00163 SAAS SAAS000181
Ligand	Iron HAMAP MF_00163 Metal-binding HAMAP MF_00163 SAAS SAAS000181
Molecular function	Hydrolase SAAS SAAS000181 HAMAP MF_00163 EMBL AAS42925.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	translation Inferred from electronic annotation. Source: HAMAP
Molecular function	iron ion binding Inferred from electronic annotation. Source: InterPro peptide deformylase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	154	1	By similarity HAMAP MF_00163
	Metal binding	110	1	Iron By similarity HAMAP MF_00163
	Metal binding	153	1	Iron By similarity HAMAP MF_00163
	Metal binding	157	1	Iron By similarity HAMAP MF_00163

Sequences

	Sequence		Length	Mass (Da)
	Q731Z2 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: 7023F5E8357677B6	FASTA	184	20,602
	10 20 30 40 50 60 MLTMKDVIRE GDPILRNVAE EVVLPASEED TNTLKEMIEF VINSQDPEMA EKYSLRPGIG 70 80 90 100 110 120 LAAPQIGISK RMIAVHVTDT DGTLYSHALF NPKIISHSVE RTYLQSGEGC LSVDREVPGY 130 140 150 160 170 180 VPRYTRITVK ATSINGEEVK LRLKGLPAIV FQHEIDHLNG VMFYDHINKE NPFAAPDDSK PLER

References

[1]

"The genome sequence of Bacillus cereus ATCC 10987 reveals metabolic adaptations and a large plasmid related to Bacillus anthracis pXO1." Rasko D.A., Ravel J., Oekstad O.A., Helgason E., Cer R.Z., Jiang L., Shores K.A., Fouts D.E., Tourasse N.J., Angiuoli S.V., Kolonay J.F., Nelson W.C., Kolstoe A.-B., Fraser C.M., Read T.D. Nucleic Acids Res. 32:977-988(2004) [PubMed: 14960714] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE017194 Genomic DNA. Translation: AAS42925.1.
RefSeq	NP_980317.1. NC_003909.8.
3D structure databases
ProteinModelPortal	Q731Z2.
SMR	Q731Z2. Positions 1-184.
ModBase	Search...
Protein-protein interaction databases
STRING	Q731Z2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBBACT00000026802; EBBACP00000026152; EBBACG00000026793.
GeneID	2751086.
GenomeReviews	Gene locus BCE_4023 in contig AE017194_GR.
KEGG	bca:BCE_4023.
NMPDR	fig|222523.1.peg.3989.
PATRIC	18856697. VBIBacCer118379_3847.
TIGR	BCE_4023.
Phylogenomic databases
eggNOG	COG0242.
GeneTree	EBGT00050000001175.
HOGENOM	HBG665227.
OMA	ADGEGCL.
ProtClustDB	PRK00150.
Family and domain databases
HAMAP	MF_00163. Pep_deformylase. [Tree]
InterPro	IPR000181. Fmet_deformylase. IPR023635. Peptide_deformylase. [Graphical view]
Gene3D	G3DSA:3.90.45.10. Fmet_deformylase. 1 hit.
KO	K01462.
PANTHER	PTHR10458. Fmet_deformylase. 1 hit.
Pfam	PF01327. Pep_deformylase. 1 hit. [Graphical view]
PIRSF	PIRSF004749. Pep_def. 1 hit.
PRINTS	PR01576. PDEFORMYLASE.
SUPFAM	SSF56420. Fmet_deformylase. 1 hit.
TIGRFAMs	TIGR00079. Pept_deformyl. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q731Z2_BACC1

Accession

Primary (citable) accession number: Q731Z2

Entry history

Integrated into UniProtKB/TrEMBL:	July 5, 2004
Last sequence update:	July 5, 2004
Last modified:	December 14, 2011
This is version 52 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)