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Q730J7 (PSD_BACC1) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 45. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phosphatidylserine decarboxylase proenzyme
EC=4.1.1.65

Cleaved into the following 2 chains:

  1. Phosphatidylserine decarboxylase alpha chain
  2. Phosphatidylserine decarboxylase beta chain
Gene names
Name:psd
Ordered Locus Names:BCE_4419
OrganismBacillus cereus (strain ATCC 10987) [Complete proteome] [HAMAP]
Taxonomic identifier222523 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus › Bacillus cereus group

Protein attributes

Sequence length262 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Phosphatidyl-L-serine = phosphatidylethanolamine + CO2. HAMAP MF_00662

Cofactor

Pyruvoyl group By similarity. HAMAP MF_00662

Pathway

Phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from CDP-diacylglycerol: step 2/2. HAMAP MF_00662

Sequence similarities

Belongs to the phosphatidylserine decarboxylase family. Type 1 subfamily.

Sequence caution

The sequence AAS43320.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
   Biological processPhospholipid biosynthesis
   LigandPyruvate
   Molecular functionDecarboxylase
Lyase
   PTMZymogen
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processphospholipid biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionphosphatidylserine decarboxylase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 225225Phosphatidylserine decarboxylase beta chain By similarity
PRO_0000029621
Chain226 – 26237Phosphatidylserine decarboxylase alpha chain By similarity
PRO_0000029622

Sites

Site225 – 2262Cleavage (non-hydrolytic) By similarity

Amino acid modifications

Modified residue2261Pyruvic acid (Ser) By similarity

Sequences

Sequence LengthMass (Da)Tools
Q730J7 [UniParc].

Last modified June 7, 2005. Version 2.
Checksum: 3682BF84E43E4645

FASTA26229,932
        10         20         30         40         50         60 
MRRTLYRLMI ELTNGRFTSY ILRKFAQSRL SSIIIPSYAK VFQINQDEME KGLKEYRTLH 

        70         80         90        100        110        120 
ELFTRKLKEG KRSIDTDASS IVSPVDGVFA DHGPIEETKT FDIKGKRYSI VDMLGNEERA 

       130        140        150        160        170        180 
QRYAGGTYMV IYLSPSHYHR IHSPLSGSVT ERFVLGRKSY PVNAAGMEYG KEPLSKNYRS 

       190        200        210        220        230        240 
VTEVNSDGEH MALVKVGAMF VNSIELLHER DTVQKGEEMA YFTFGSTVVL LFEKDMIEVV 

       250        260 
QELKSGQELR LGEKIATRLA HK

« Hide

References

[1]"The genome sequence of Bacillus cereus ATCC 10987 reveals metabolic adaptations and a large plasmid related to Bacillus anthracis pXO1."
Rasko D.A., Ravel J., Oekstad O.A., Helgason E., Cer R.Z., Jiang L., Shores K.A., Fouts D.E., Tourasse N.J., Angiuoli S.V., Kolonay J.F., Nelson W.C., Kolstoe A.-B., Fraser C.M., Read T.D.
Nucleic Acids Res. 32:977-988(2004) [PubMed: 14960714] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 10987.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE017194 Genomic DNA. Translation: AAS43320.1. Different initiation.
RefSeqNP_980712.1. NC_003909.8.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGQ730J7.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBBACT00000027657; EBBACP00000027007; EBBACG00000027648.
GeneID2748321.
GenomeReviewsGene locus BCE_4419 in contig AE017194_GR.
KEGGbca:BCE_4419.
NMPDRfig|222523.1.peg.4384.
PATRIC18857474. VBIBacCer118379_4234.
TIGRBCE_4419.

Phylogenomic databases

eggNOGCOG0688.
GeneTreeEBGT00050000001988.
HOGENOMHBG302256.
ProtClustDBPRK03140.

Enzyme and pathway databases

BioCycBCER405917:BCE_4419-MONOMER.

Family and domain databases

HAMAPMF_00662. PS_decarb_type1.
[Tree]
InterProIPR003817. PS_Dcarbxylase.
IPR005221. PS_decarb.
[Graphical view]
KOK01613.
PANTHERPTHR10067. PS_decarb. 1 hit.
PfamPF02666. PS_Dcarbxylase. 1 hit.
[Graphical view]
TIGRFAMsTIGR00163. PS_decarb. 1 hit.
ProtoNetSearch...

Entry information

Entry namePSD_BACC1
AccessionPrimary (citable) accession number: Q730J7
Entry history
Integrated into UniProtKB/Swiss-Prot: June 7, 2005
Last sequence update: June 7, 2005
Last modified: January 25, 2012
This is version 45 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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