Q72Z96 (ACKA_BACC1) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Acetate kinase
EC=2.7.2.1

Alternative name(s):
Acetokinase

Gene names

Name:	ackA
Ordered Locus Names:	BCE_4773

Organism

Bacillus cereus (strain ATCC 10987) [Complete proteome] [HAMAP]

Taxonomic identifier

222523 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus › Bacillus cereus group

Protein attributes

Sequence length	397 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + acetate = ADP + acetyl phosphate. HAMAP MF_00020 ATP + propanoate = ADP + propanoyl phosphate. HAMAP MF_00020
Pathway	Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. HAMAP MF_00020
Subcellular location	Cytoplasm By similarity HAMAP MF_00020.
Sequence similarities	Belongs to the acetokinase family.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	organic acid metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW acetate kinase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 397	397	Acetate kinase HAMAP MF_00020		PRO_0000107526

Sequences

	Sequence		Length	Mass (Da)
	Q72Z96 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: 3F8816167EBA9B99	FASTA	397	43,232
	10 20 30 40 50 60 MSKIIAINAG SSSLKFQLFE MPSETVLTKG LVERIGLEDS IFTITVDGEK QKEITNIPDH 70 80 90 100 110 120 AVAVNMLLKK LTENGIVKSL DEIGGIGHRV VHGGEKFADS VLITDEVLAD IEELSDLAPL 130 140 150 160 170 180 HNPANVVGIK AFQEVLPNVP AVAVFDTAFH QTMPESAFLY SLPYEYYEKF GIRKYGFHGT 190 200 210 220 230 240 SHKYVTERAA ELLGRPLESL SLLSCHLGNG ASIAAVEGGK SIDTSMGFTP LAGVTMGTRS 250 260 270 280 290 300 GNIDPALIPY IMEKTGQTVE EVVNVLNKKS GMLGLTGYSS DLRDIIAKEE EGDHRAKVAL 310 320 330 340 350 360 DVFVSRIHKY IGSYTARMKG VDAIIFTAGV GENSAIIRER VLEGLEYMGV YFDAKRNNVF 370 380 390 GEEAFINFPH SPVKIIVIPT DEEVMIARDV LRLGNIG

References

[1]

"The genome sequence of Bacillus cereus ATCC 10987 reveals metabolic adaptations and a large plasmid related to Bacillus anthracis pXO1." Rasko D.A., Ravel J., Oekstad O.A., Helgason E., Cer R.Z., Jiang L., Shores K.A., Fouts D.E., Tourasse N.J., Angiuoli S.V., Kolonay J.F., Nelson W.C., Kolstoe A.-B., Fraser C.M., Read T.D. Nucleic Acids Res. 32:977-988(2004) [PubMed: 14960714] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 10987.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE017194 Genomic DNA. Translation: AAS43674.1.
RefSeq	NP_981066.1. NC_003909.8.
3D structure databases
ProteinModelPortal	Q72Z96.
SMR	Q72Z96. Positions 3-395.
ModBase	Search...
Protein-protein interaction databases
STRING	Q72Z96.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBBACT00000026236; EBBACP00000025586; EBBACG00000026227.
GeneID	2750002.
GenomeReviews	Gene locus BCE_4773 in contig AE017194_GR.
KEGG	bca:BCE_4773.
PATRIC	18858158. VBIBacCer118379_4574.
TIGR	BCE_4773.
Phylogenomic databases
eggNOG	COG0282.
GeneTree	EBGT00050000000769.
HOGENOM	HBG285863.
OMA	LIDMTNE.
ProtClustDB	PRK00180.
Enzyme and pathway databases
BioCyc	BCER405917:BCE_4773-MONOMER.
Family and domain databases
HAMAP	MF_00020. Acetate_kinase. [Tree]
InterPro	IPR004372. Ac/Proprionate_kinase. IPR000890. Aliphatic_acid_kin_short-chain. IPR023865. Aliphatic_acid_kinase_CS. [Graphical view]
KO	K00925.
PANTHER	PTHR21060. Acetate_kin. 1 hit.
Pfam	PF00871. Acetate_kinase. 1 hit. [Graphical view]
PIRSF	PIRSF000722. Acetate_prop_kin. 1 hit.
PRINTS	PR00471. ACETATEKNASE.
TIGRFAMs	TIGR00016. AckA. 1 hit.
PROSITE	PS01075. ACETATE_KINASE_1. 1 hit. PS01076. ACETATE_KINASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ACKA_BACC1

Accession

Primary (citable) accession number: Q72Z96

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 1, 2005
Last sequence update:	July 5, 2004
Last modified:	January 25, 2012
This is version 53 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program