Reviewed, UniProtKB/Swiss-Prot Q72Z96 (ACKA_BACC1)

Names and origin

Protein names

Recommended name:
    Acetate kinase
    EC=2.7.2.1
Alternative name(s):
    Acetokinase

Gene names

Name:	ackA
Ordered Locus Names:	BCE_4773

Organism

Bacillus cereus (strain ATCC 10987) [Complete proteome] [HAMAP]

Taxonomic identifier

222523 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus › Bacillus cereus group

Protein attributes

Sequence length	397 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	ATP + acetate = ADP + acetyl phosphate. HAMAP MF_00020 ATP + propanoate = ADP + propanoyl phosphate. HAMAP MF_00020
Pathway	Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. HAMAP MF_00020
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the acetokinase family.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	organic acid metabolic process Inferred from electronic annotation. Source: InterPro phosphorylation Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW acetate kinase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 397	397	Acetate kinase HAMAP MF_00020		PRO_0000107526

Sequences

	Sequence		Length	Mass (Da)
	Q72Z96-1 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: 3F8816167EBA9B99	FASTA	397	43,232
	10 20 30 40 50 60 MSKIIAINAG SSSLKFQLFE MPSETVLTKG LVERIGLEDS IFTITVDGEK QKEITNIPDH 70 80 90 100 110 120 AVAVNMLLKK LTENGIVKSL DEIGGIGHRV VHGGEKFADS VLITDEVLAD IEELSDLAPL 130 140 150 160 170 180 HNPANVVGIK AFQEVLPNVP AVAVFDTAFH QTMPESAFLY SLPYEYYEKF GIRKYGFHGT 190 200 210 220 230 240 SHKYVTERAA ELLGRPLESL SLLSCHLGNG ASIAAVEGGK SIDTSMGFTP LAGVTMGTRS 250 260 270 280 290 300 GNIDPALIPY IMEKTGQTVE EVVNVLNKKS GMLGLTGYSS DLRDIIAKEE EGDHRAKVAL 310 320 330 340 350 360 DVFVSRIHKY IGSYTARMKG VDAIIFTAGV GENSAIIRER VLEGLEYMGV YFDAKRNNVF 370 380 390 GEEAFINFPH SPVKIIVIPT DEEVMIARDV LRLGNIG

References

[1]

"The genome sequence of Bacillus cereus ATCC 10987 reveals metabolic adaptations and a large plasmid related to Bacillus anthracis pXO1." Rasko D.A., Ravel J., Oekstad O.A., Helgason E., Cer R.Z., Jiang L., Shores K.A., Fouts D.E., Tourasse N.J., Angiuoli S.V., Kolonay J.F., Nelson W.C., Kolstoe A.-B., Fraser C.M., Read T.D. Nucleic Acids Res. 32:977-988(2004) [PubMed: 14960714] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE017194 Genomic DNA. Translation: AAS43674.1.
RefSeq	NP_981066.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q72Z96.
Genome annotation databases
GeneID	2750002.
GenomeReviews	Gene locus BCE_4773 in contig AE017194_GR.
KEGG	bca:BCE_4773.
TIGR	BCE_4773.
Phylogenomic databases
HOGENOM	Q72Z96.
OMA	SSDFRDV.
Family and domain databases
HAMAP	MF_00020. [Tree]
InterPro	IPR000890. Acetate/butyrate_kinase. IPR004372. AckA. [Graphical view]
PANTHER	PTHR21060. Acetate_kin. 1 hit. PTHR21060:SF11. AckA. 1 hit.
Pfam	PF00871. Acetate_kinase. 1 hit. [Graphical view]
PIRSF	PIRSF000722. Acetate_prop_kin. 1 hit.
PRINTS	PR00471. ACETATEKNASE.
TIGRFAMs	TIGR00016. ackA. 1 hit.
PROSITE	PS01075. ACETATE_KINASE_1. 1 hit. PS01076. ACETATE_KINASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ACKA_BACC1

Accession

Primary (citable) accession number: Q72Z96

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 1, 2005
Last sequence update:	July 5, 2004
Last modified:	November 3, 2009
This is version 38 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)