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Q72RH2 (TRPF_LEPIC) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 55. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
N-(5'-phosphoribosyl)anthranilate isomerase

Short name=PRAI
EC=5.3.1.24
Gene names
Name:trpF
Ordered Locus Names:LIC_11773
OrganismLeptospira interrogans serogroup Icterohaemorrhagiae serovar copenhageni (strain Fiocruz L1-130) [Complete proteome] [HAMAP]
Taxonomic identifier267671 [NCBI]
Taxonomic lineageBacteriaSpirochaetesSpirochaetalesLeptospiraceaeLeptospira

Protein attributes

Sequence length213 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate. HAMAP-Rule MF_00135

Pathway

Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 3/5. HAMAP-Rule MF_00135

Sequence similarities

Belongs to the TrpF family.

Sequence caution

The sequence AAS70362.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Aromatic amino acid biosynthesis
Tryptophan biosynthesis
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processtryptophan biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Molecular_functionphosphoribosylanthranilate isomerase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 213213N-(5'-phosphoribosyl)anthranilate isomerase HAMAP-Rule MF_00135
PRO_0000154361

Sequences

Sequence LengthMass (Da)Tools
Q72RH2 [UniParc].

Last modified August 30, 2005. Version 2.
Checksum: AFA2F32647276991

FASTA21324,066
        10         20         30         40         50         60 
MITNSLQKTK VKICGIKDLE IAKICKEEGA DYIGFNFVSS SPRKIELSNA QKIVEYYKSE 

        70         80         90        100        110        120 
KNSPEIVLLF YQNSFEEIES ITSVLDHDLV QWVWDDPLIN RKKLLYKRQI CSYRVQTQIH 

       130        140        150        160        170        180 
DQDLKDIEAE FLILDSYSKG VGGGTGETFN WELISKVKRK FLLAGGLDPS NVVNAIEIVK 

       190        200        210 
PFGVDVASGV ESSPGIKDPQ KVIQFIRNVK STS 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE016823 Genomic DNA. Translation: AAS70362.1. Different initiation.
RefSeqYP_001725.1. NC_005823.1.

3D structure databases

ProteinModelPortalQ72RH2.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING267671.LIC11773.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAS70362; AAS70362; LIC_11773.
GeneID2772407.
KEGGlic:LIC11773.
PATRIC22375941. VBILepInt6257_2136.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK01817.
OMAISALHCE.
OrthoDBEOG6N94DF.
ProtClustDBCLSK574243.

Enzyme and pathway databases

BioCycLINT267671:GHQI-1768-MONOMER.
UniPathwayUPA00035; UER00042.

Family and domain databases

Gene3D3.20.20.70. 1 hit.
HAMAPMF_00135. PRAI.
InterProIPR013785. Aldolase_TIM.
IPR001240. PRAI_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view]
PfamPF00697. PRAI. 1 hit.
[Graphical view]
SUPFAMSSF51366. SSF51366. 1 hit.
ProtoNetSearch...

Entry information

Entry nameTRPF_LEPIC
AccessionPrimary (citable) accession number: Q72RH2
Entry history
Integrated into UniProtKB/Swiss-Prot: August 30, 2005
Last sequence update: August 30, 2005
Last modified: February 19, 2014
This is version 55 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways