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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Leptospira interrogans serogroup Icterohaemorrhagiae serovar copenhageni (strain Fiocruz L1-130)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciLINT267671:G1G07-2267-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:LIC_12102
OrganismiLeptospira interrogans serogroup Icterohaemorrhagiae serovar copenhageni (strain Fiocruz L1-130)
Taxonomic identifieri267671 [NCBI]
Taxonomic lineageiBacteriaSpirochaetesLeptospiralesLeptospiraceaeLeptospira
Proteomesi
  • UP000007037 Componenti: Chromosome I

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001515701 – 586Arginine--tRNA ligaseAdd BLAST586

Proteomic databases

PaxDbiQ72QL1
PRIDEiQ72QL1

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi267671.LIC12102

Structurei

3D structure databases

ProteinModelPortaliQ72QL1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi133 – 143"HIGH" regionAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C75 Bacteria
COG0018 LUCA
KOiK01887

Family and domain databases

CDDicd00671 ArgRS_core, 1 hit
Gene3Di3.30.1360.70, 1 hit
3.40.50.620, 1 hit
HAMAPiMF_00123 Arg_tRNA_synth, 1 hit
InterProiView protein in InterPro
IPR001278 Arg-tRNA-ligase
IPR005148 Arg-tRNA-synth_N
IPR036695 Arg-tRNA-synth_N_sf
IPR035684 ArgRS_core
IPR008909 DALR_anticod-bd
IPR014729 Rossmann-like_a/b/a_fold
IPR009080 tRNAsynth_Ia_anticodon-bd
PANTHERiPTHR11956 PTHR11956, 1 hit
PfamiView protein in Pfam
PF03485 Arg_tRNA_synt_N, 1 hit
PF05746 DALR_1, 1 hit
PF00750 tRNA-synt_1d, 1 hit
PRINTSiPR01038 TRNASYNTHARG
SMARTiView protein in SMART
SM01016 Arg_tRNA_synt_N, 1 hit
SM00836 DALR_1, 1 hit
SUPFAMiSSF47323 SSF47323, 1 hit
SSF55190 SSF55190, 1 hit
TIGRFAMsiTIGR00456 argS, 1 hit

Sequencei

Sequence statusi: Complete.

Q72QL1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKENETLKQI VLKTLEESVN SLISSFPEVE KEAFKIKIEY SRDEKFGDYS
60 70 80 90 100
TSFALENSKL LKRNPIQVSK ELVEILQKRT DLFEKVDFTP PGFVNFRIST
110 120 130 140 150
SFLLNYIETS VLSGNYFPKV DLPLKINLEF VSANPTGPLN IVSARAAANG
160 170 180 190 200
DTMASLLKAI GHNVDKEFYI NDYGNQVFLL GVSTLVRIRE LKGEEGTQQE
210 220 230 240 250
TTDDTPIEII LEKNILPAEG YRGEYIKDIA SSLLKDPKKN VTIENLLKQK
260 270 280 290 300
KYKELAELCA VWTIENNLIW QRKDLDAFGV EFDCYFSERT LHEADKVLSV
310 320 330 340 350
MKDLEKSGKI FQEDGKKVFR STEYGDDKDR VVVRDDGRPT YLLADIAYHK
360 370 380 390 400
DKIERGYDKI YDIWGPDHHG YISRLSGAVQ SLGYKKENFK VIISQQVNLL
410 420 430 440 450
ESGQKVKMSK RAGSFQTMSD LIGFLGKHGK DVGRYFFVMR SLDAPLDFDL
460 470 480 490 500
DLAKDESDKN PVFYLQYAHA RICSIFKEVG DQTSKEAAAI LEMSEERKRL
510 520 530 540 550
LFWIARFPEE IFDSANAMEP HRVTNYLQSF AKAFTSFYLA KDNRLKDASK
560 570 580
EVRLGLARIC LAAKNVLAEG LKLIGVSAPE RMEKEN
Length:586
Mass (Da):66,821
Last modified:August 10, 2010 - v2
Checksum:iE2B7702058C628AC
GO

Sequence cautioni

The sequence AAS70673 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE016823 Genomic DNA Translation: AAS70673.1 Different initiation.
RefSeqiWP_000662000.1, NC_005823.1

Genome annotation databases

EnsemblBacteriaiAAS70673; AAS70673; LIC_12102
KEGGilic:LIC_12102

Similar proteinsi

Entry informationi

Entry nameiSYR_LEPIC
AccessioniPrimary (citable) accession number: Q72QL1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 15, 2005
Last sequence update: August 10, 2010
Last modified: May 23, 2018
This is version 87 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

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